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The map label for this gene is mcp [H]

Identifier: 21243181

GI number: 21243181

Start: 2848963

End: 2850621

Strand: Reverse

Name: mcp [H]

Synonym: XAC2448

Alternate gene names: 21243181

Gene position: 2850621-2848963 (Counterclockwise)

Preceding gene: 21243183

Following gene: 21243180

Centisome position: 55.08

GC content: 65.58

Gene sequence:

>1659_bases
ATGTTAGGCAACTTCAGAATCGGAACCAGACTGATCGTGGCATTCCTGATCGTCTCGGCCATCGGCGCATGCATCGGGTG
GGTGGGCTATTCCAACTCCAGCCGCATCAGTGCGCTGTCGAGCTCGTTGTACGAGCGCGAGTTGCTCGGCATGTCCCACG
TCAAGGAAGCCAACATCAACCTCATCTATGCCGGCCGCGCGCGCGCCAACCTGTTGTTGGCCAGCAGTGCAGAAGAGCGC
CAGTCGCATGTGCAGAACATCGACAAATACACCGCCAAGGTGGTCGATCACATGGCCCGTGCGCGGGAAAGCTTCCAGAG
CGAGGAAGGCAAGAACAAGCTGGCGCAATTCGATCGCGCCTGGCAGAAGTATCTGGACGAGCGCGGCCGCTTCATCGAGG
TCGCCAACCGCGAAGCGCTGCGCGAGGCCAATCCGGAACTGGCCGCGCTATCGCGCGCGGTCCGTGCCAGCTCGGACGAA
GTGGATAACCTGATGACCGACCTGAGCGGCCTGCGCGAGCGCAGCGCCGCGGCGGCCAACGCGGAAGCCGGTGCGATCCA
CGCGCGCAGTTCCAGGCTGCTGGTCGCCATCATCTGCAGCGGCGTGTTGCTCGGCGCCATTCTCGGTGTGGTAATCAGCC
GCAGCGTCACCGGGCCGATCCGCCGCGCGGTGGCGGTGGCCAACGGCTTGTCGGAAGGCGATCTCACCATGCGTATCGAT
GTGCACGGCCGCGACGAAACCGCGCAATTGCTCGAAGCGATGCGCACCATGGTCGGGAAGCTGTCGCAGGTGGTCGGCGA
GGTCAATACCAGCGCCGAAACCCTTGCCAGCGCGTCGGAAGAAGTCAGCGCCACCGCGCAGTCGCTGTCGCAGGCGGCAA
GCGAACAGGCCGCCGGTGTGGAAGAGACCAGTGCTTCGCTGGAGCAGATGACCGCATCGATCAGCCAGAACACCGAGAAC
GCGCGTATCACCGACGGCATGGCCACCCAGGCCGCCAAGGAGACCGTGGAGGGTGGCGAAGCGGTGGTTGCCACCACCCA
GGCGATGAAGCAGATCGCGCAGAAGATCGGCATCATCGACGACATCGCGTACCAGACCAATCTGCTCGCGCTCAATGCCG
CGATCGAAGCCGCGCGCGCCGGCGAACATGGCAAGGGGTTTGCCGTGGTCGCCGCGGAGGTGCGCAAGCTGGCCGAACGC
AGCCAGGTGGCCGCGCAGGAAATTGGCGAGGTGGCCAGTTCCAGCGTGGAATTGGCGGACCGCGCGGGCCGTTTGCTGGA
TTCGATCGTGCCCAGCATCAAGCGCACCTCCGACCTGGTGCAGGAAATATCCGCTGCCTCCGAGGAGCAATCTTCCGGCG
TCAGCCAGATCAATTCGGCGGTCGTGCAGTTGAGCCAGACCACCCAGCAGAACGCCAGCGCATCCGAAGAACTGGCCGCC
ACTGCCGAGGAAATGAGCGCGCAGGCCGAACAGCTGCAGCAGAGCATGGCGTTCTTCCGGCTGGGCGGGCAGGGCGCGCC
GACTGCGCCGCCCAAGCGCGGCAAGCAGGTCGCCGCGCGACCGGCGCGTGCGGCGGGCACGCGTGGCTGGCGCAGCAACG
CAGCGCCGGCGTATGCGATGTCCGAGGGCCCCGACGAAGGCCAGTTCGCGCGTTTCTGA

Upstream 100 bases:

>100_bases
GCGATGGGTTAGACCAGCCGTAGCGCCATGCGATACGCGCAGCGCCATCGCCATCCTGCAGCGCATGTCGCCCACGCACC
CTTTTTGAGAGAACTCCCCA

Downstream 100 bases:

>100_bases
GAGAGCGACCAATGACCGCACCGACGCTTGATGTGATGCCCGGCGACGCCGATGTCGCCGCGCAATATCTGACCTTTCAA
CTGGATGGCGAAACCTTCGC

Product: chemotaxis protein

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MLGNFRIGTRLIVAFLIVSAIGACIGWVGYSNSSRISALSSSLYERELLGMSHVKEANINLIYAGRARANLLLASSAEER
QSHVQNIDKYTAKVVDHMARARESFQSEEGKNKLAQFDRAWQKYLDERGRFIEVANREALREANPELAALSRAVRASSDE
VDNLMTDLSGLRERSAAAANAEAGAIHARSSRLLVAIICSGVLLGAILGVVISRSVTGPIRRAVAVANGLSEGDLTMRID
VHGRDETAQLLEAMRTMVGKLSQVVGEVNTSAETLASASEEVSATAQSLSQAASEQAAGVEETSASLEQMTASISQNTEN
ARITDGMATQAAKETVEGGEAVVATTQAMKQIAQKIGIIDDIAYQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQVAAQEIGEVASSSVELADRAGRLLDSIVPSIKRTSDLVQEISAASEEQSSGVSQINSAVVQLSQTTQQNASASEELAA
TAEEMSAQAEQLQQSMAFFRLGGQGAPTAPPKRGKQVAARPARAAGTRGWRSNAAPAYAMSEGPDEGQFARF

Sequences:

>Translated_552_residues
MLGNFRIGTRLIVAFLIVSAIGACIGWVGYSNSSRISALSSSLYERELLGMSHVKEANINLIYAGRARANLLLASSAEER
QSHVQNIDKYTAKVVDHMARARESFQSEEGKNKLAQFDRAWQKYLDERGRFIEVANREALREANPELAALSRAVRASSDE
VDNLMTDLSGLRERSAAAANAEAGAIHARSSRLLVAIICSGVLLGAILGVVISRSVTGPIRRAVAVANGLSEGDLTMRID
VHGRDETAQLLEAMRTMVGKLSQVVGEVNTSAETLASASEEVSATAQSLSQAASEQAAGVEETSASLEQMTASISQNTEN
ARITDGMATQAAKETVEGGEAVVATTQAMKQIAQKIGIIDDIAYQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQVAAQEIGEVASSSVELADRAGRLLDSIVPSIKRTSDLVQEISAASEEQSSGVSQINSAVVQLSQTTQQNASASEELAA
TAEEMSAQAEQLQQSMAFFRLGGQGAPTAPPKRGKQVAARPARAAGTRGWRSNAAPAYAMSEGPDEGQFARF
>Mature_552_residues
MLGNFRIGTRLIVAFLIVSAIGACIGWVGYSNSSRISALSSSLYERELLGMSHVKEANINLIYAGRARANLLLASSAEER
QSHVQNIDKYTAKVVDHMARARESFQSEEGKNKLAQFDRAWQKYLDERGRFIEVANREALREANPELAALSRAVRASSDE
VDNLMTDLSGLRERSAAAANAEAGAIHARSSRLLVAIICSGVLLGAILGVVISRSVTGPIRRAVAVANGLSEGDLTMRID
VHGRDETAQLLEAMRTMVGKLSQVVGEVNTSAETLASASEEVSATAQSLSQAASEQAAGVEETSASLEQMTASISQNTEN
ARITDGMATQAAKETVEGGEAVVATTQAMKQIAQKIGIIDDIAYQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAER
SQVAAQEIGEVASSSVELADRAGRLLDSIVPSIKRTSDLVQEISAASEEQSSGVSQINSAVVQLSQTTQQNASASEELAA
TAEEMSAQAEQLQQSMAFFRLGGQGAPTAPPKRGKQVAARPARAAGTRGWRSNAAPAYAMSEGPDEGQFARF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=530, Percent_Identity=31.1320754716981, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI2367378, Length=342, Percent_Identity=40.0584795321637, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788194, Length=288, Percent_Identity=41.6666666666667, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1788195, Length=325, Percent_Identity=38.1538461538462, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1789453, Length=337, Percent_Identity=34.7181008902077, Blast_Score=155, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58343; Mature: 58343

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGNFRIGTRLIVAFLIVSAIGACIGWVGYSNSSRISALSSSLYERELLGMSHVKEANIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
LIYAGRARANLLLASSAEERQSHVQNIDKYTAKVVDHMARARESFQSEEGKNKLAQFDRA
EEEECCCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQKYLDERGRFIEVANREALREANPELAALSRAVRASSDEVDNLMTDLSGLRERSAAAAN
HHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
AEAGAIHARSSRLLVAIICSGVLLGAILGVVISRSVTGPIRRAVAVANGLSEGDLTMRID
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEE
VHGRDETAQLLEAMRTMVGKLSQVVGEVNTSAETLASASEEVSATAQSLSQAASEQAAGV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EETSASLEQMTASISQNTENARITDGMATQAAKETVEGGEAVVATTQAMKQIAQKIGIID
HHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHH
DIAYQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERSQVAAQEIGEVASSSVELAD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAGRLLDSIVPSIKRTSDLVQEISAASEEQSSGVSQINSAVVQLSQTTQQNASASEELAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
TAEEMSAQAEQLQQSMAFFRLGGQGAPTAPPKRGKQVAARPARAAGTRGWRSNAAPAYAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCC
SEGPDEGQFARF
CCCCCCCCCCCC
>Mature Secondary Structure
MLGNFRIGTRLIVAFLIVSAIGACIGWVGYSNSSRISALSSSLYERELLGMSHVKEANIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCE
LIYAGRARANLLLASSAEERQSHVQNIDKYTAKVVDHMARARESFQSEEGKNKLAQFDRA
EEEECCCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQKYLDERGRFIEVANREALREANPELAALSRAVRASSDEVDNLMTDLSGLRERSAAAAN
HHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
AEAGAIHARSSRLLVAIICSGVLLGAILGVVISRSVTGPIRRAVAVANGLSEGDLTMRID
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEE
VHGRDETAQLLEAMRTMVGKLSQVVGEVNTSAETLASASEEVSATAQSLSQAASEQAAGV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EETSASLEQMTASISQNTENARITDGMATQAAKETVEGGEAVVATTQAMKQIAQKIGIID
HHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHH
DIAYQTNLLALNAAIEAARAGEHGKGFAVVAAEVRKLAERSQVAAQEIGEVASSSVELAD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAGRLLDSIVPSIKRTSDLVQEISAASEEQSSGVSQINSAVVQLSQTTQQNASASEELAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
TAEEMSAQAEQLQQSMAFFRLGGQGAPTAPPKRGKQVAARPARAAGTRGWRSNAAPAYAM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCHHHCCCCCCCCCCCCCCCC
SEGPDEGQFARF
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]