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The map label for this gene is suhB [H]

Identifier: 21243119

GI number: 21243119

Start: 2779574

End: 2780407

Strand: Direct

Name: suhB [H]

Synonym: XAC2385

Alternate gene names: 21243119

Gene position: 2779574-2780407 (Clockwise)

Preceding gene: 21243115

Following gene: 77748652

Centisome position: 53.71

GC content: 64.51

Gene sequence:

>834_bases
ATGCAGAAACCCGCCGTCACCGTCATGGTCAAAGCCGCCCGCCTCGCCGGCAATGTGCTGTTGCGCGGTATCAACAAGCT
CGATGCGCTCAATGTGGTGCAGAAAGGCCGTATGGACTACGCCAGCGAAGTCGATGCCGATGCCGAGAAGGTCATCATCA
AGGAACTCAAGCGCGGCTACCCCGAATACGCCGTGTTCGGCGAAGAAGGCGGCGTGCAGGGCGGCAAGAGTGGCCGCTAC
ACCTGGGTCATCGATCCGCTCGACGGCACCAGCAACTATCTGCGCGGTTTCCCGCATTACTGCGTGTCGATCGCGCTGGT
GGAAAACGGCGAACCGACCGATGCGGTGATCTTCGACCCGTTGCGCAACGAGTTGTTCACCGCCAGCCGCGGCGCCGGCG
CGGTGCTCAACGATCGCCGCATCCGCATTGCAGAGCGCAAGGATCTGGAAGGGGCCATGGTCCACACCGGCTTTCCGCCG
CGCGAACGCGCGCGCGCCAGTGCACAGCTCAAGTGCGTGGATGCGCTGCTGGTGCAGGCCGAAGACGTGCGACGCACCGG
CTCGGCGGCGCTGGACCTGGCGTATGTCGCCTGCGGCCGCGCCGATGCCTATTTCGAAGCGGGGGTCAAAGCCTGGGACA
TCGCCGCTGGTGTGTTGCTGGTGCGCGAGGCCGGTGGCCGCGTCTGCGACTACAAGGGCGCCACCCCGCCGCGCATGGAC
AACATGGGCCCTGAGACGCAGCAGATCGTGGCCGGCAACATCAAGATCAGCGATGCATTGCAAAAGGTCATCGTCAACAC
CGGCTACGCCCGCGAGTTCGACGCCAAGTTCTGA

Upstream 100 bases:

>100_bases
CTGTTCGGCCGTAGATGGTAAACTGCGCGGCCGGCTTTCGCGCCGGACCGCTCTTTTACCTTCGCCATTGTCCGATTCTG
CCTTCACGGGAGCTTTAACC

Downstream 100 bases:

>100_bases
TCGCCCCCACCCCGGGTTCTAATCGACGCCTGCACAACGTAGGAGCGCGCCCGAGCGCGAGGAGCGTTCCTTGCAAAGCC
TCTCGCGACCGGGATCGCTC

Product: extragenic supressor protein SuhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MQKPAVTVMVKAARLAGNVLLRGINKLDALNVVQKGRMDYASEVDADAEKVIIKELKRGYPEYAVFGEEGGVQGGKSGRY
TWVIDPLDGTSNYLRGFPHYCVSIALVENGEPTDAVIFDPLRNELFTASRGAGAVLNDRRIRIAERKDLEGAMVHTGFPP
RERARASAQLKCVDALLVQAEDVRRTGSAALDLAYVACGRADAYFEAGVKAWDIAAGVLLVREAGGRVCDYKGATPPRMD
NMGPETQQIVAGNIKISDALQKVIVNTGYAREFDAKF

Sequences:

>Translated_277_residues
MQKPAVTVMVKAARLAGNVLLRGINKLDALNVVQKGRMDYASEVDADAEKVIIKELKRGYPEYAVFGEEGGVQGGKSGRY
TWVIDPLDGTSNYLRGFPHYCVSIALVENGEPTDAVIFDPLRNELFTASRGAGAVLNDRRIRIAERKDLEGAMVHTGFPP
RERARASAQLKCVDALLVQAEDVRRTGSAALDLAYVACGRADAYFEAGVKAWDIAAGVLLVREAGGRVCDYKGATPPRMD
NMGPETQQIVAGNIKISDALQKVIVNTGYAREFDAKF
>Mature_277_residues
MQKPAVTVMVKAARLAGNVLLRGINKLDALNVVQKGRMDYASEVDADAEKVIIKELKRGYPEYAVFGEEGGVQGGKSGRY
TWVIDPLDGTSNYLRGFPHYCVSIALVENGEPTDAVIFDPLRNELFTASRGAGAVLNDRRIRIAERKDLEGAMVHTGFPP
RERARASAQLKCVDALLVQAEDVRRTGSAALDLAYVACGRADAYFEAGVKAWDIAAGVLLVREAGGRVCDYKGATPPRMD
NMGPETQQIVAGNIKISDALQKVIVNTGYAREFDAKF

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=229, Percent_Identity=34.9344978165939, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=30.8300395256917, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI221625487, Length=253, Percent_Identity=30.8300395256917, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI221625507, Length=142, Percent_Identity=32.3943661971831, Blast_Score=89, Evalue=4e-18,
Organism=Escherichia coli, GI1788882, Length=258, Percent_Identity=45.3488372093023, Blast_Score=230, Evalue=9e-62,
Organism=Escherichia coli, GI1790659, Length=231, Percent_Identity=27.7056277056277, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193202570, Length=235, Percent_Identity=28.0851063829787, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193202572, Length=231, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320493, Length=203, Percent_Identity=35.4679802955665, Blast_Score=133, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321836, Length=212, Percent_Identity=32.0754716981132, Blast_Score=120, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21357329, Length=207, Percent_Identity=38.1642512077295, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24664926, Length=244, Percent_Identity=34.0163934426229, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24664922, Length=274, Percent_Identity=30.6569343065693, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21357303, Length=216, Percent_Identity=34.2592592592593, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21357957, Length=256, Percent_Identity=30.859375, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24664918, Length=265, Percent_Identity=29.4339622641509, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 30051; Mature: 30051

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKPAVTVMVKAARLAGNVLLRGINKLDALNVVQKGRMDYASEVDADAEKVIIKELKRGY
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCC
PEYAVFGEEGGVQGGKSGRYTWVIDPLDGTSNYLRGFPHYCVSIALVENGEPTDAVIFDP
CCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCEEEEEEEECCCCCCEEEECH
LRNELFTASRGAGAVLNDRRIRIAERKDLEGAMVHTGFPPRERARASAQLKCVDALLVQA
HHHHHHHCCCCCCCEECCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
EDVRRTGSAALDLAYVACGRADAYFEAGVKAWDIAAGVLLVREAGGRVCDYKGATPPRMD
HHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHEEEEECCCCCEEECCCCCCCCCC
NMGPETQQIVAGNIKISDALQKVIVNTGYAREFDAKF
CCCCCCHHEEECCEEHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQKPAVTVMVKAARLAGNVLLRGINKLDALNVVQKGRMDYASEVDADAEKVIIKELKRGY
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHCCC
PEYAVFGEEGGVQGGKSGRYTWVIDPLDGTSNYLRGFPHYCVSIALVENGEPTDAVIFDP
CCEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCCEEEEEEEECCCCCCEEEECH
LRNELFTASRGAGAVLNDRRIRIAERKDLEGAMVHTGFPPRERARASAQLKCVDALLVQA
HHHHHHHCCCCCCCEECCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
EDVRRTGSAALDLAYVACGRADAYFEAGVKAWDIAAGVLLVREAGGRVCDYKGATPPRMD
HHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHEEEEECCCCCEEECCCCCCCCCC
NMGPETQQIVAGNIKISDALQKVIVNTGYAREFDAKF
CCCCCCHHEEECCEEHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]