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The map label for this gene is argC

Identifier: 21243080

GI number: 21243080

Start: 2741538

End: 2742488

Strand: Reverse

Name: argC

Synonym: XAC2346

Alternate gene names: 21243080

Gene position: 2742488-2741538 (Counterclockwise)

Preceding gene: 21243081

Following gene: 21243079

Centisome position: 52.99

GC content: 64.46

Gene sequence:

>951_bases
ATGACTGTTCAACCAAAGACCATCGGCATTGTCGGCGCCCGCGGGCATACCGGCTCGGAATTGATCAAACTGGTTGCGGC
GCACCCGCAGCTGCACTTGAGCTTCGTGTCCTCGCGCGAGCTGGCCGGGCAGCGCGTGGCCGAGCATAACGATGCCTACC
AGGGGCAGTTGCGCTACGAGAACCTGGATGCCGACGCGGTGGCCGTCAAGGCTGCCGACGTGGTGATCCTGGCGCTGCCC
AATGGCAAGGCAGCGCCCTTCGTCGCCGCGATCGACGCAGCAACGCCGCAGACGCTGGTGATCGATCTGTCGGCAGACTA
TCGCTTCGATCCGGCCTGGTACTACGGCTTGCCTGAGCTGACGCGCGGCAGCTACGCCGGACAAAGACGCATCAGCAACC
CGGGCTGTTATGCCACCGCGATGCAGCTGACCATCGCGCCACTGCTCGACCAGTTGGCCGGGCCGCCGCAGTGTTTCGGC
GTCTCCGGGTATTCGGGCGCGGGTACCACGCCCTCGGACAAGAACAACCCCGAGTTGCTCTCCAATAATTTGATGCCGTA
TGCGCTGACCAACCACATGCACGAGCGCGAGGTGTCTGCGCAGCTCGGCGTGCCGGTGGAGTTCATGCCGCACGTGGCGC
CGCATTTCCGCGGCATCACCATGACCGTCAATCTGTGGCTGCAGCAGCCGCTGACGCGCGAGCAGATCCAGGCGCGTTAT
ACGCAGCGTTATGCCGACGAGCCGTTGATCGAGATCGTCGACGAAGCGCCTTGGGTGAGCCGCATCGCCGGCAAGCACGG
TGTGCAGATTGGCGGGGTGACGCTGGCGCCCGGCAACAAGCGCGTGGTGGTGGTGGCGACGCTGGACAACCTGCTCAAGG
GTGCAGCGACGCAGGCGATGCAGAACCTCAACCTGGCGCTGGGCTGGGACGAGTTGATGGCAATTCGTTGA

Upstream 100 bases:

>100_bases
ACGCCGACGGTACGCTGCGCGATACCGTGGTGTTTTCCATCATCGATACGGAATGGGCAGGGGTTAAACGCCACCTGCAG
TTCCGCCTGGAAGCAAACGC

Downstream 100 bases:

>100_bases
TGCGAGTCCCTCGCAAGAGCCTGCACATCCCTGTGCAGGGATTTAACGATGCGAGTCCCTCGCAACAGCCCGCACATCCC
TGTGCAGGGATTTAACGATG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTVQPKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDADAVAVKAADVVILALP
NGKAAPFVAAIDAATPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQRRISNPGCYATAMQLTIAPLLDQLAGPPQCFG
VSGYSGAGTTPSDKNNPELLSNNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR

Sequences:

>Translated_316_residues
MTVQPKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDADAVAVKAADVVILALP
NGKAAPFVAAIDAATPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQRRISNPGCYATAMQLTIAPLLDQLAGPPQCFG
VSGYSGAGTTPSDKNNPELLSNNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR
>Mature_315_residues
TVQPKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYENLDADAVAVKAADVVILALPN
GKAAPFVAAIDAATPQTLVIDLSADYRFDPAWYYGLPELTRGSYAGQRRISNPGCYATAMQLTIAPLLDQLAGPPQCFGV
SGYSGAGTTPSDKNNPELLSNNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARYT
QRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAMQNLNLALGWDELMAIR

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=339, Percent_Identity=30.0884955752212, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320913, Length=323, Percent_Identity=47.0588235294118, Blast_Score=295, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_XANAC (Q8PK31)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642662.1
- ProteinModelPortal:   Q8PK31
- SMR:   Q8PK31
- GeneID:   1156417
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2346
- NMPDR:   fig|190486.1.peg.2306
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   XAXO190486:XAC2346-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 34190; Mature: 34059

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQPKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYE
CCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEC
NLDADAVAVKAADVVILALPNGKAAPFVAAIDAATPQTLVIDLSADYRFDPAWYYGLPEL
CCCCCEEEEEEEEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCEECCCEECCCCHH
TRGSYAGQRRISNPGCYATAMQLTIAPLLDQLAGPPQCFGVSGYSGAGTTPSDKNNPELL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHH
SNNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
HCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCEEEEEEEEECCCCCHHHHHHHH
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAM
HHHHCCCHHHHHHHCCCHHHHHHCCCCEEECCEEECCCCCEEEEEEEHHHHHHHHHHHHH
QNLNLALGWDELMAIR
HHCCEEECHHHHHCCC
>Mature Secondary Structure 
TVQPKTIGIVGARGHTGSELIKLVAAHPQLHLSFVSSRELAGQRVAEHNDAYQGQLRYE
CCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEC
NLDADAVAVKAADVVILALPNGKAAPFVAAIDAATPQTLVIDLSADYRFDPAWYYGLPEL
CCCCCEEEEEEEEEEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCEECCCEECCCCHH
TRGSYAGQRRISNPGCYATAMQLTIAPLLDQLAGPPQCFGVSGYSGAGTTPSDKNNPELL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHH
SNNLMPYALTNHMHEREVSAQLGVPVEFMPHVAPHFRGITMTVNLWLQQPLTREQIQARY
HCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHCCEEEEEEEEECCCCCHHHHHHHH
TQRYADEPLIEIVDEAPWVSRIAGKHGVQIGGVTLAPGNKRVVVVATLDNLLKGAATQAM
HHHHCCCHHHHHHHCCCHHHHHHCCCCEEECCEEECCCCCEEEEEEEHHHHHHHHHHHHH
QNLNLALGWDELMAIR
HHCCEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217