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The map label for this gene is metX

Identifier: 21243067

GI number: 21243067

Start: 2724930

End: 2726132

Strand: Direct

Name: metX

Synonym: XAC2332

Alternate gene names: 21243067

Gene position: 2724930-2726132 (Clockwise)

Preceding gene: 21243066

Following gene: 21243068

Centisome position: 52.65

GC content: 64.92

Gene sequence:

>1203_bases
ATGACTGAATTCATCCCTGCCGGCACGCTGTACCACGCCCTGCCCTCGCCATTTCCGATGAAACGCGGTGGCGTGCTGCA
TCAGGCACGCGTGGCGTACGAGACCTGGGGCACGCTGGCCGCAGATCGCAGCAACGCGATCCTGATCGTCACCGGCCTGT
CGCCCAATGCGCACGCAGCGGCAAACCAGGCCAACCCCGAGCCGGGCTGGTGGGAAGCAATGCTAGGGCCGGGCAAGCCG
ATCGATACCGCACGCTGGTTCGTGGTCTGCGTCAATTCGTTAGGCAGTTGCAAGGGCTCGACCGGGCCGGCCTCGGTAAA
CCCAGACACCGGCGCGCCGTATCGCCTCAGCTTTCCGGACCTGTCGATCGAAGACGTGGCCGATGCCGCAGCCGACGTGG
TTCACGCGTTGGGCATCGCGCAGCTGGCTTGCCTGATCGGCAACTCGATGGGCGGCATGACCGCGCTGGCGCTGTTGCTG
CGCCATCCCGGCATCGCGCGCAGCCATATCAATATTTCCGGCAGCGCGCAGGCATTGCCGTTTTCGATCGCGATACGCTC
GTTGCAACGCGAGGCGATCCGGCTGGATCCACACTGGAACGGCGGCCACTACGACGATGTGCGCTACCCGGAATCGGGCA
TGCGCATGGCGCGCAAACTCGGCGTGATCACGTATCGTTCGGCGCTGGAATGGGACGGCCGTTTCGGCCGCGTGCGGCTG
GATTCCGAGCAGGCAGCCGATGATCCGTTCGGGCTCGAATTCCAGGTGGAAAGCTATCTGGAAGGCCACGCGCGCCGCTT
CGTGCGTTTTTTCGACCCAAACTGCTATCTGTATCTGAGCCGCTCGATGGACTGGTTCGACCTGGCCGAGTATGTCGAGG
AAAGACCGGTTGCCGGCTCTGCCATCGACAATGCCCGTGCAGATGCACGGCCCGCTTCCGCCAAGCCACAGACCGGCGTC
TCGACCGCCGACACCGTGCTTGCCGGCCTGGCACGTATCCGCATCGCGCGTGCGCTGGCGATCGGCGCCAACACCGACAT
CCTGTTCCCGGTGCAGCAGCAGGAACAGATCGCCGACGGCCTGCGCGCCGGCGGCGCCGATGCGCAATTCATCGGCCTGG
ATTCGCCGCAAGGCCACGACGCGTTCCTGGTCGATTTCGCCCGGTTCGGCCCAGCGGTGAGCGACTTTTTGCAGGACTGT
TGA

Upstream 100 bases:

>100_bases
TAGGTGCGGAGCCGGATGCTCCGTTGTCTACATGGGGCATGCAGACGAACGTACGCAACGCCGGCCAGCACCATCGCGCA
GTGCCAGCTAGAATTGGCCC

Downstream 100 bases:

>100_bases
GCTCCTTGAAGCTCGCTCTGCGCTGCCGAATATCGGCCGATGTTGCTGCAATACGGTAACCATCACCGCTGTTTTGCCGG
CTGAGCAATTGGTGCGTGAT

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTEFIPAGTLYHALPSPFPMKRGGVLHQARVAYETWGTLAADRSNAILIVTGLSPNAHAAANQANPEPGWWEAMLGPGKP
IDTARWFVVCVNSLGSCKGSTGPASVNPDTGAPYRLSFPDLSIEDVADAAADVVHALGIAQLACLIGNSMGGMTALALLL
RHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDVRYPESGMRMARKLGVITYRSALEWDGRFGRVRL
DSEQAADDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVEERPVAGSAIDNARADARPASAKPQTGV
STADTVLAGLARIRIARALAIGANTDILFPVQQQEQIADGLRAGGADAQFIGLDSPQGHDAFLVDFARFGPAVSDFLQDC

Sequences:

>Translated_400_residues
MTEFIPAGTLYHALPSPFPMKRGGVLHQARVAYETWGTLAADRSNAILIVTGLSPNAHAAANQANPEPGWWEAMLGPGKP
IDTARWFVVCVNSLGSCKGSTGPASVNPDTGAPYRLSFPDLSIEDVADAAADVVHALGIAQLACLIGNSMGGMTALALLL
RHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDVRYPESGMRMARKLGVITYRSALEWDGRFGRVRL
DSEQAADDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVEERPVAGSAIDNARADARPASAKPQTGV
STADTVLAGLARIRIARALAIGANTDILFPVQQQEQIADGLRAGGADAQFIGLDSPQGHDAFLVDFARFGPAVSDFLQDC
>Mature_399_residues
TEFIPAGTLYHALPSPFPMKRGGVLHQARVAYETWGTLAADRSNAILIVTGLSPNAHAAANQANPEPGWWEAMLGPGKPI
DTARWFVVCVNSLGSCKGSTGPASVNPDTGAPYRLSFPDLSIEDVADAAADVVHALGIAQLACLIGNSMGGMTALALLLR
HPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDVRYPESGMRMARKLGVITYRSALEWDGRFGRVRLD
SEQAADDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVEERPVAGSAIDNARADARPASAKPQTGVS
TADTVLAGLARIRIARALAIGANTDILFPVQQQEQIADGLRAGGADAQFIGLDSPQGHDAFLVDFARFGPAVSDFLQDC

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=219, Percent_Identity=31.5068493150685, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_XANAC (Q8PK44)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642649.1
- ProteinModelPortal:   Q8PK44
- SMR:   Q8PK44
- GeneID:   1156403
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2332
- NMPDR:   fig|190486.1.peg.2293
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   XAXO190486:XAC2332-MONOMER
- BRENDA:   2.3.1.31
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 43133; Mature: 43002

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 379-379

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFIPAGTLYHALPSPFPMKRGGVLHQARVAYETWGTLAADRSNAILIVTGLSPNAHAA
CCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCCC
ANQANPEPGWWEAMLGPGKPIDTARWFVVCVNSLGSCKGSTGPASVNPDTGAPYRLSFPD
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
LSIEDVADAAADVVHALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCH
FSIAIRSLQREAIRLDPHWNGGHYDDVRYPESGMRMARKLGVITYRSALEWDGRFGRVRL
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHHCCCCCCCEEEE
DSEQAADDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVEERPVAGS
CCHHCCCCCCCCEEEHHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHCCCCCC
AIDNARADARPASAKPQTGVSTADTVLAGLARIRIARALAIGANTDILFPVQQQEQIADG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCEEECCHHHHHHHHH
LRAGGADAQFIGLDSPQGHDAFLVDFARFGPAVSDFLQDC
HHCCCCCEEEEECCCCCCCCCEEEEHHHHCHHHHHHHHCC
>Mature Secondary Structure 
TEFIPAGTLYHALPSPFPMKRGGVLHQARVAYETWGTLAADRSNAILIVTGLSPNAHAA
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEEEECCCCCCCCC
ANQANPEPGWWEAMLGPGKPIDTARWFVVCVNSLGSCKGSTGPASVNPDTGAPYRLSFPD
CCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCC
LSIEDVADAAADVVHALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCH
FSIAIRSLQREAIRLDPHWNGGHYDDVRYPESGMRMARKLGVITYRSALEWDGRFGRVRL
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHHCCCCCCCEEEE
DSEQAADDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVEERPVAGS
CCHHCCCCCCCCEEEHHHHHHHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHCCCCCC
AIDNARADARPASAKPQTGVSTADTVLAGLARIRIARALAIGANTDILFPVQQQEQIADG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCEEECCHHHHHHHHH
LRAGGADAQFIGLDSPQGHDAFLVDFARFGPAVSDFLQDC
HHCCCCCEEEEECCCCCCCCCEEEEHHHHCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12024217