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The map label for this gene is lytT [H]

Identifier: 21242876

GI number: 21242876

Start: 2496349

End: 2497041

Strand: Reverse

Name: lytT [H]

Synonym: XAC2141

Alternate gene names: 21242876

Gene position: 2497041-2496349 (Counterclockwise)

Preceding gene: 21242877

Following gene: 21242874

Centisome position: 48.25

GC content: 62.77

Gene sequence:

>693_bases
GTGATCGTGGAAGATTCTGAGCTGGCCCGCTTCGAACTGGAGCACCAGCTCAAGGGCTACCCGCAGCTGCGTGTGCTGGG
CCACGCCGATGATGTGGACAGTGCGGTGCAGTTGATCGAATCGGCTACGCCGGAGGTGGTCTTTCTGGATATCGACCTTC
CCGGCGGCAACGCGTTCGATGTGCTGGAGCGCCTGAGCCGGGTACCGCGCATCATCTTCACCACCGCCTTCGACGCGCAT
GCGCTCAAGGCGTTCGGTTACAACACGGTGGACTACCTGCTCAAGCCAATCGAACCGCAGCGGCTTGCCCAGGCGATCGA
GAAACTAGGCGACGCGGTTGCCACCCCCCCGGTGCGGCGCGCGATGGACAGTGCCATCTTCATCAAGGACGGCGAGCACT
GCTTCCTGGTCAAGCCGCGTGATGTGCGGTTGATCGAGGCGGTCGGCAACTACAGCCGGGTGTACTTCCAGAACCATGCG
CCATTGCTGTACCGGCCGCTCGGCGCGATTGAAACGCAACTGGCGCCGGACAAATTCTTCCGCGCCAGCCGCAAGTACAT
CGTCAATCTCGACTTCGTGGAGCAGGTCGCACCGTGGAGCAACGGTGGCCTGATGCTGACCCTGCGCGGTGGGCTGGAAG
TGGACGTGTCCCGCCGCCAGAGCGTGCGCTTCAGAGAGCTGCTTAGCCTTTAG

Upstream 100 bases:

>100_bases
TGCGGCTCTCGTTCGGATCACGTGCCGGTCTGGAATTACATGAAGAAGGCACGTGGGTGGTGGCACATGTATGGATTGGA
GAAGGCGCGTGATTGAAGCG

Downstream 100 bases:

>100_bases
CGTCCAGCCGCTTCTCAGTGGCTGGCAAACGTAACTGCCAGTGCCCAGCTAAGGGTGGATGGCGCACAGGAACCACCGAG
CATGCGTGTGGCATATGCGG

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIVEDSELARFELEHQLKGYPQLRVLGHADDVDSAVQLIESATPEVVFLDIDLPGGNAFDVLERLSRVPRIIFTTAFDAH
ALKAFGYNTVDYLLKPIEPQRLAQAIEKLGDAVATPPVRRAMDSAIFIKDGEHCFLVKPRDVRLIEAVGNYSRVYFQNHA
PLLYRPLGAIETQLAPDKFFRASRKYIVNLDFVEQVAPWSNGGLMLTLRGGLEVDVSRRQSVRFRELLSL

Sequences:

>Translated_230_residues
MIVEDSELARFELEHQLKGYPQLRVLGHADDVDSAVQLIESATPEVVFLDIDLPGGNAFDVLERLSRVPRIIFTTAFDAH
ALKAFGYNTVDYLLKPIEPQRLAQAIEKLGDAVATPPVRRAMDSAIFIKDGEHCFLVKPRDVRLIEAVGNYSRVYFQNHA
PLLYRPLGAIETQLAPDKFFRASRKYIVNLDFVEQVAPWSNGGLMLTLRGGLEVDVSRRQSVRFRELLSL
>Mature_230_residues
MIVEDSELARFELEHQLKGYPQLRVLGHADDVDSAVQLIESATPEVVFLDIDLPGGNAFDVLERLSRVPRIIFTTAFDAH
ALKAFGYNTVDYLLKPIEPQRLAQAIEKLGDAVATPPVRRAMDSAIFIKDGEHCFLVKPRDVRLIEAVGNYSRVYFQNHA
PLLYRPLGAIETQLAPDKFFRASRKYIVNLDFVEQVAPWSNGGLMLTLRGGLEVDVSRRQSVRFRELLSL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=242, Percent_Identity=30.1652892561983, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082052, Length=240, Percent_Identity=30, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25935; Mature: 25935

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVEDSELARFELEHQLKGYPQLRVLGHADDVDSAVQLIESATPEVVFLDIDLPGGNAFD
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHH
VLERLSRVPRIIFTTAFDAHALKAFGYNTVDYLLKPIEPQRLAQAIEKLGDAVATPPVRR
HHHHHHHCCEEEEEECCCHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHH
AMDSAIFIKDGEHCFLVKPRDVRLIEAVGNYSRVYFQNHAPLLYRPLGAIETQLAPDKFF
HHCCEEEEECCCEEEEECCCCEEEEEHHCCCEEEEECCCCCEEEECCCHHHHHCCHHHHH
RASRKYIVNLDFVEQVAPWSNGGLMLTLRGGLEVDVSRRQSVRFRELLSL
HCCCCEEEEEHHHHHHCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MIVEDSELARFELEHQLKGYPQLRVLGHADDVDSAVQLIESATPEVVFLDIDLPGGNAFD
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHH
VLERLSRVPRIIFTTAFDAHALKAFGYNTVDYLLKPIEPQRLAQAIEKLGDAVATPPVRR
HHHHHHHCCEEEEEECCCHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHH
AMDSAIFIKDGEHCFLVKPRDVRLIEAVGNYSRVYFQNHAPLLYRPLGAIETQLAPDKFF
HHCCEEEEECCCEEEEECCCCEEEEEHHCCCEEEEECCCCCEEEECCCHHHHHCCHHHHH
RASRKYIVNLDFVEQVAPWSNGGLMLTLRGGLEVDVSRRQSVRFRELLSL
HCCCCEEEEEHHHHHHCCCCCCCEEEEECCCCEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]