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The map label for this gene is flp [H]

Identifier: 21242875

GI number: 21242875

Start: 2494830

End: 2496203

Strand: Direct

Name: flp [H]

Synonym: XAC2140

Alternate gene names: 21242875

Gene position: 2494830-2496203 (Clockwise)

Preceding gene: 21242870

Following gene: 21242879

Centisome position: 48.2

GC content: 64.34

Gene sequence:

>1374_bases
ATGAAGACAATTGCGATGATGCTGCTGGCCACCGCGCTGAGCATGGCTGGCACGGTCCGCGCGACGGAGACCACACCGCC
GGCATCAGCCACGGTCGAATTGGCGCGCGAGGCCGCGGCGTTTTTCAAGGACAGCCAGCCCGGCGGCGTGGTGCTGGTGA
CGCGCGCTGATCAGGTACTGCTGCGCCAGGCCTACGGCATGGCGGACATCGAAAATGGCGTGGCCATGCAACCGGACGCG
GCATTGCGACTGGCCTCGGTCAGCAAGCAGTTCACCGCCTTGGCGGTCCTGCAGCTGGTGCAGGCGGGCAGGTTGCAACT
GGATGCCTGCTTGGAGTCGCTGGACCCGGCGCTGAGCGGCCCGCTCGCCAAGGTCACCGTGCAGCAGCTGCTCACGCATA
CCTCCGGCATCAAGAATGTCAGCAGCATCGCCGCCTCGCGCGCGGCGCGGCGGGAGGACACCGATGCGCGGAGCCTGATG
AACTACTTCAAGGACCTGCCGCTGGAGTTCGCTGCGGGCACGCGCTTTCGTTACAGCAACTCCAACTACATCGTGCTGAC
CTATCTGATCGAACGCATCACCGCTCAGCCCTACCCCTTCTACATGCAGCGGTCGGTCTTCCAGCCGTTGGGCATGCTGC
ATACCCGCTACGATAACCATCTCACCGTGATCGCCAAGCGGGCGCATGGCTATCGCCGCGCCCAGGGCCAATTGCAGAAC
GCGGACTTCATCAGCATGTCGCAGCCGCAAGGCGCGGGCGGTCTGATCAGCACGGTGGACGATCTGGCGATCTGGCACCG
CGCATTGCGCGACGGCTTGCCGGTGTCGGCATCGCTGCTGGCGCAAGCGATGCGCAAGACCACGTTGGCCGATGGCAGCG
CCTCGCCCTACGGCTTCGGCTGGATCATCGGCCAGGTAAACGGCATGGCCGACGTAGAGCATGGCGGCTTCATCAACGGC
TTCAACAGCTATGTGGTGCGCGTGAGACAGCCGGACGTCTTCGTGACCGTGTTGACCAATGCCGAGTTCCTGGATCCGAC
CAACCTGAGCGTGCGTCTGGCCGCCATCGCCGCCGGGCATGCCTATGCGGCGACGGTTGCACTGCGCAGCCAGGACCGCG
CATGGCTGGGCCGTTACCACTTTGCTGCAGACGATGTACGCGTGCTTGCAGAAGTGGACGGCGCACTGCAACTGCAGCGC
GAGGGAGAAGACCCGGTTGCAGTGCTGCCGCATGCCGACGGCCGTTACTACCTGGGCGAGAGCCTGGATGCGTTGAGCTT
CAAGAACGGCGGCGATGGCAAGGCAGTCATGACAATGCACGATCGCTTGATGGGTGACAGCAGCGGCACCCGCGAATCGA
ACAAGGGCAACTGA

Upstream 100 bases:

>100_bases
AACGACCGTTCGATGCCCGTCCCGACCGCACGTCATGCATCGCTGGGCGCTGCGCGGCTCCGCTCCCAAGCTGCGCTCCA
TCCACTGAAGGAGCAGGTTT

Downstream 100 bases:

>100_bases
CAAACCAGTGCACAGCTGTCCTCCGGCGTAACCGGTGCCCGGAGTCCGCATATGCCACACGCATGCTCGGTGGTTCCTGT
GCGCCATCCACCCTTAGCTG

Product: D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MKTIAMMLLATALSMAGTVRATETTPPASATVELAREAAAFFKDSQPGGVVLVTRADQVLLRQAYGMADIENGVAMQPDA
ALRLASVSKQFTALAVLQLVQAGRLQLDACLESLDPALSGPLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLM
NYFKDLPLEFAAGTRFRYSNSNYIVLTYLIERITAQPYPFYMQRSVFQPLGMLHTRYDNHLTVIAKRAHGYRRAQGQLQN
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFGWIIGQVNGMADVEHGGFING
FNSYVVRVRQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGHAYAATVALRSQDRAWLGRYHFAADDVRVLAEVDGALQLQR
EGEDPVAVLPHADGRYYLGESLDALSFKNGGDGKAVMTMHDRLMGDSSGTRESNKGN

Sequences:

>Translated_457_residues
MKTIAMMLLATALSMAGTVRATETTPPASATVELAREAAAFFKDSQPGGVVLVTRADQVLLRQAYGMADIENGVAMQPDA
ALRLASVSKQFTALAVLQLVQAGRLQLDACLESLDPALSGPLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLM
NYFKDLPLEFAAGTRFRYSNSNYIVLTYLIERITAQPYPFYMQRSVFQPLGMLHTRYDNHLTVIAKRAHGYRRAQGQLQN
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFGWIIGQVNGMADVEHGGFING
FNSYVVRVRQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGHAYAATVALRSQDRAWLGRYHFAADDVRVLAEVDGALQLQR
EGEDPVAVLPHADGRYYLGESLDALSFKNGGDGKAVMTMHDRLMGDSSGTRESNKGN
>Mature_457_residues
MKTIAMMLLATALSMAGTVRATETTPPASATVELAREAAAFFKDSQPGGVVLVTRADQVLLRQAYGMADIENGVAMQPDA
ALRLASVSKQFTALAVLQLVQAGRLQLDACLESLDPALSGPLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLM
NYFKDLPLEFAAGTRFRYSNSNYIVLTYLIERITAQPYPFYMQRSVFQPLGMLHTRYDNHLTVIAKRAHGYRRAQGQLQN
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFGWIIGQVNGMADVEHGGFING
FNSYVVRVRQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGHAYAATVALRSQDRAWLGRYHFAADDVRVLAEVDGALQLQR
EGEDPVAVLPHADGRYYLGESLDALSFKNGGDGKAVMTMHDRLMGDSSGTRESNKGN

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=353, Percent_Identity=24.0793201133144, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17550934, Length=318, Percent_Identity=26.4150943396226, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533026, Length=334, Percent_Identity=23.6526946107784, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 49427; Mature: 49427

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIAMMLLATALSMAGTVRATETTPPASATVELAREAAAFFKDSQPGGVVLVTRADQVL
CHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHH
LRQAYGMADIENGVAMQPDAALRLASVSKQFTALAVLQLVQAGRLQLDACLESLDPALSG
HHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHCC
PLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLMNYFKDLPLEFAAGTRFRYSN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCEEEECC
SNYIVLTYLIERITAQPYPFYMQRSVFQPLGMLHTRYDNHLTVIAKRAHGYRRAQGQLQN
CCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHCCCCCC
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFG
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEE
WIIGQVNGMADVEHGGFINGFNSYVVRVRQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGH
EEEEECCCCEECCCCCEEECCCEEEEEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCC
AYAATVALRSQDRAWLGRYHFAADDVRVLAEVDGALQLQREGEDPVAVLPHADGRYYLGE
HHEEEEEECCCCCHHHHHEEECHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCEECCC
SLDALSFKNGGDGKAVMTMHDRLMGDSSGTRESNKGN
CCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKTIAMMLLATALSMAGTVRATETTPPASATVELAREAAAFFKDSQPGGVVLVTRADQVL
CHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHH
LRQAYGMADIENGVAMQPDAALRLASVSKQFTALAVLQLVQAGRLQLDACLESLDPALSG
HHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHCC
PLAKVTVQQLLTHTSGIKNVSSIAASRAARREDTDARSLMNYFKDLPLEFAAGTRFRYSN
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEECCCCEEEECC
SNYIVLTYLIERITAQPYPFYMQRSVFQPLGMLHTRYDNHLTVIAKRAHGYRRAQGQLQN
CCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHCCCCCC
ADFISMSQPQGAGGLISTVDDLAIWHRALRDGLPVSASLLAQAMRKTTLADGSASPYGFG
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEE
WIIGQVNGMADVEHGGFINGFNSYVVRVRQPDVFVTVLTNAEFLDPTNLSVRLAAIAAGH
EEEEECCCCEECCCCCEEECCCEEEEEEECCCEEEEEECCCCCCCCCCCEEEEEEEECCC
AYAATVALRSQDRAWLGRYHFAADDVRVLAEVDGALQLQREGEDPVAVLPHADGRYYLGE
HHEEEEEECCCCCHHHHHEEECHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCCEECCC
SLDALSFKNGGDGKAVMTMHDRLMGDSSGTRESNKGN
CCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA