BacMap

Definition	Xanthomonas axonopodis pv. citri str. 306 chromosome, complete genome.
Accession	NC_003919
Length	5,175,554

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The map label for this gene is fabG [H]

Identifier: 21242864

GI number: 21242864

Start: 2485192

End: 2485986

Strand: Direct

Name: fabG [H]

Synonym: XAC2129

Alternate gene names: 21242864

Gene position: 2485192-2485986 (Clockwise)

Preceding gene: 21242863

Following gene: 21242865

Centisome position: 48.02

GC content: 63.52

Gene sequence:

>795_bases
ATGGATCTCGGAATCAAACAGCGGATCGCCCTCATCAGTGGCGGCGACTCCGGCATGGGCAAGGAGACTGCGCGCCAGCT
GCTCGAAGCCGGCGTGCGCGTGGCGATCACCGATCTTCCCAATGGCACGCTCGACCAGGCAGTGGCCGAGTTGTCCGGCC
TGGGGGAGATCATCGCCATCGAAGGCGATGTGACGCAGGAACAGGACGTCATCCACATCTGGACCCAGGTGCGCGCGCAA
CTGGGGGAACCGGATATCTACGTCAACGCCGCCGGCGTCACCGGCGATTTCCTGGAGGTCAGCGATGCCGGCTGGCTCGA
AACGCTGGACATCAACCTGATGGGCGCGGTGCGCATGTGCCGCCAGGCCATTCCTGCCATGCGTCGCAAGCAGTGGGGGC
GGATTGTGTTGTTCGCGTCCGAAGATGCAGTGCAGCCGTACGTGGATGAGTTGGCCTACTGCGCGTCCAAGGCCGGCATC
CTGAGCCTGGCCAAGGGGCTGTCAAAGGCCTATGGCGCCGACAATGTATTGGTCAACACGGTGTCGCCCGCGTTCATCGC
AACGCCGATGACCGACAAGATGATGCAAAAACGCGCACACGAGAACGGAACCAGTGTCGAAGAAGCCATTGCCTCGTTCC
TGGATGAAGAACGCCCCGGCATGGCGCTGAAGCGGCGCGGCCGGCCAGAGGAAGTGGCCTCCGTCGTCGCATTCCTGTGC
TCGGAGCGCGCAAGCTTCATCAACGGCGCCGGCGTGCGCGTGGACTCGGGCTCGGTATTCACCATCGCTGGCTGA

Upstream 100 bases:

>100_bases
CGGCACTGACCCAGATGGCACTCGCGCTGCGCACCGCAGAACGTTTCCTTGCGCGCTAGCAGCACTGCGCCACCACGTAC
TCAACGACCAGGAGCTCAAT

Downstream 100 bases:

>100_bases
GGCGGGCGGCGCGGTGCAGCGGCAAGTGAAATCAAAGAGAAGCACGAGCAATATTTGACATAATATACATTATGCGAAAT
TGGCCGCGTCCCCGTACGGG

Product: 3-ketoacyl-acyl carrier protein reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDLGIKQRIALISGGDSGMGKETARQLLEAGVRVAITDLPNGTLDQAVAELSGLGEIIAIEGDVTQEQDVIHIWTQVRAQ
LGEPDIYVNAAGVTGDFLEVSDAGWLETLDINLMGAVRMCRQAIPAMRRKQWGRIVLFASEDAVQPYVDELAYCASKAGI
LSLAKGLSKAYGADNVLVNTVSPAFIATPMTDKMMQKRAHENGTSVEEAIASFLDEERPGMALKRRGRPEEVASVVAFLC
SERASFINGAGVRVDSGSVFTIAG

Sequences:

>Translated_264_residues
MDLGIKQRIALISGGDSGMGKETARQLLEAGVRVAITDLPNGTLDQAVAELSGLGEIIAIEGDVTQEQDVIHIWTQVRAQ
LGEPDIYVNAAGVTGDFLEVSDAGWLETLDINLMGAVRMCRQAIPAMRRKQWGRIVLFASEDAVQPYVDELAYCASKAGI
LSLAKGLSKAYGADNVLVNTVSPAFIATPMTDKMMQKRAHENGTSVEEAIASFLDEERPGMALKRRGRPEEVASVVAFLC
SERASFINGAGVRVDSGSVFTIAG
>Mature_264_residues
MDLGIKQRIALISGGDSGMGKETARQLLEAGVRVAITDLPNGTLDQAVAELSGLGEIIAIEGDVTQEQDVIHIWTQVRAQ
LGEPDIYVNAAGVTGDFLEVSDAGWLETLDINLMGAVRMCRQAIPAMRRKQWGRIVLFASEDAVQPYVDELAYCASKAGI
LSLAKGLSKAYGADNVLVNTVSPAFIATPMTDKMMQKRAHENGTSVEEAIASFLDEERPGMALKRRGRPEEVASVVAFLC
SERASFINGAGVRVDSGSVFTIAG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.8850574712644, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI19923817, Length=269, Percent_Identity=30.1115241635688, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=29.811320754717, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=29.5275590551181, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=27.3809523809524, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4758504, Length=267, Percent_Identity=28.0898876404494, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=25.3787878787879, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=27.4111675126904, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI83715985, Length=268, Percent_Identity=27.2388059701493, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=27.6422764227642, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.2553191489362, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI109715829, Length=252, Percent_Identity=24.2063492063492, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=25.5208333333333, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=23.9130434782609, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=203, Percent_Identity=26.6009852216749, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7657478, Length=222, Percent_Identity=28.8288288288288, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=27.3224043715847, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=23.4615384615385, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=265, Percent_Identity=28.6792452830189, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=29.7297297297297, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=30.1158301158301, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=28.2868525896414, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=25.6704980842912, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=29.7709923664122, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787905, Length=260, Percent_Identity=26.1538461538462, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=25.1908396946565, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=251, Percent_Identity=27.8884462151394, Blast_Score=71, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=29.5275590551181, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17538182, Length=264, Percent_Identity=28.4090909090909, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=26.7441860465116, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=27.906976744186, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=24.7058823529412, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.171875, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=26.2172284644195, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=26.5625, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=27.843137254902, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=26.1029411764706, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=24.9084249084249, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=27.6515151515151, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=23.8434163701068, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=259, Percent_Identity=27.027027027027, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=30.5882352941176, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=29.1338582677165, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=25.7028112449799, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=27.2373540856031, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357041, Length=259, Percent_Identity=28.957528957529, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=28.0155642023346, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI18859837, Length=248, Percent_Identity=27.8225806451613, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=27.0676691729323, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644337, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221331218, Length=202, Percent_Identity=27.7227722772277, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665243, Length=202, Percent_Identity=27.7227722772277, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 28199; Mature: 28199

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIKQRIALISGGDSGMGKETARQLLEAGVRVAITDLPNGTLDQAVAELSGLGEIIAI
CCCCHHHEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCEEEE
EGDVTQEQDVIHIWTQVRAQLGEPDIYVNAAGVTGDFLEVSDAGWLETLDINLMGAVRMC
ECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEEECHHHHHHHHHH
RQAIPAMRRKQWGRIVLFASEDAVQPYVDELAYCASKAGILSLAKGLSKAYGADNVLVNT
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
VSPAFIATPMTDKMMQKRAHENGTSVEEAIASFLDEERPGMALKRRGRPEEVASVVAFLC
CCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHH
SERASFINGAGVRVDSGSVFTIAG
HHHHHHHCCCCEEECCCCEEEECC
>Mature Secondary Structure
MDLGIKQRIALISGGDSGMGKETARQLLEAGVRVAITDLPNGTLDQAVAELSGLGEIIAI
CCCCHHHEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCEEEE
EGDVTQEQDVIHIWTQVRAQLGEPDIYVNAAGVTGDFLEVSDAGWLETLDINLMGAVRMC
ECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEECCCCCEEEECHHHHHHHHHH
RQAIPAMRRKQWGRIVLFASEDAVQPYVDELAYCASKAGILSLAKGLSKAYGADNVLVNT
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
VSPAFIATPMTDKMMQKRAHENGTSVEEAIASFLDEERPGMALKRRGRPEEVASVVAFLC
CCCCEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHH
SERASFINGAGVRVDSGSVFTIAG
HHHHHHHCCCCEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]