Click here to switch to the map view.

The map label for this gene is nfuA

Identifier: 21242852

GI number: 21242852

Start: 2473791

End: 2474390

Strand: Direct

Name: nfuA

Synonym: XAC2117

Alternate gene names: 21242852

Gene position: 2473791-2474390 (Clockwise)

Preceding gene: 21242847

Following gene: 21242853

Centisome position: 47.8

GC content: 67.0

Gene sequence:

>600_bases
ATGATCCAGATATCCGACAAAGCCCAGACCTATTTCCGCAAGCTCATCGAACGCGAGGGCGTGCCCGGCATGGGCGTGCG
CCTGAGCGCGGTGGATGCGGGCACCCCGCGCGCCGATGCACGGCTTGAGTTCGCCGAACCGGCGGACCTGAGCGGCGACG
AATGGGCGATCGACTGCGACGGCTTCACCTTGTATGTCGTCGCCGCCAGCGTGCCCTGGATGGATGGCGCCGAAATCGAC
TACGTCACCCAGTCCACCGGCAACCAGCAGCTCACCATCAAGGCGCCCAAGATCAAGGGAGAAGCGCCCGCAGAGTCGGC
TTCGATGGTCGAGCGTGTGCGCTGGGTGGTGGAAAACGAGATCAACCCGCAGCTGGCATCGCATGGCGGACGCGTGGCTG
TGCAGGAAGTCTCCGCCGAGGGCGTGGTGTTGCTGCGCTTCGGCGGCGGTTGCCACGGCTGCGGCATGGCCGACGTGACC
TTGAAGCAGGGCATCGAAAAGACCCTGATGGGGCGCGTGCCCGGCGTGACTGCGGTGCGCGACGCGACCGACCACGCCAC
CGGCGACGCCCCCTACATTCCGCGCGACAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
CAGATCGGTCATGACGGTCTCGCAGGGGTGGCGGACGGTGCGCCCACCAGGATCACGGTGTTCCATGAGCGAGGGCGCTT
TGAGCGGTAGAATAACCCGC

Downstream 100 bases:

>100_bases
TTCCGCACCACCGGTGACAACGGCTGCCGATCTGCTGCAGGCACTGCGCGCGCGCATGCCCGGCAAGCTCATTGTGGATC
GGCGCACCGGCCTTCCGTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCDGFTLYVVAASVPWMDGAEID
YVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENEINPQLASHGGRVAVQEVSAEGVVLLRFGGGCHGCGMADVT
LKQGIEKTLMGRVPGVTAVRDATDHATGDAPYIPRDSAA

Sequences:

>Translated_199_residues
MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCDGFTLYVVAASVPWMDGAEID
YVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENEINPQLASHGGRVAVQEVSAEGVVLLRFGGGCHGCGMADVT
LKQGIEKTLMGRVPGVTAVRDATDHATGDAPYIPRDSAA
>Mature_199_residues
MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCDGFTLYVVAASVPWMDGAEID
YVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENEINPQLASHGGRVAVQEVSAEGVVLLRFGGGCHGCGMADVT
LKQGIEKTLMGRVPGVTAVRDATDHATGDAPYIPRDSAA

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=192, Percent_Identity=43.2291666666667, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_XANAC (Q8PKQ2)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642434.1
- ProteinModelPortal:   Q8PKQ2
- SMR:   Q8PKQ2
- GeneID:   1156188
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2117
- NMPDR:   fig|190486.1.peg.2078
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- ProtClustDB:   CLSK446553
- BioCyc:   XAXO190486:XAC2117-MONOMER
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- ProDom:   PD002830

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 21172; Mature: 21172

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCD
CEEECHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCEEEEEC
GFTLYVVAASVPWMDGAEIDYVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENE
CEEEEEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
INPQLASHGGRVAVQEVSAEGVVLLRFGGGCHGCGMADVTLKQGIEKTLMGRVPGVTAVR
CCHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEC
DATDHATGDAPYIPRDSAA
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIQISDKAQTYFRKLIEREGVPGMGVRLSAVDAGTPRADARLEFAEPADLSGDEWAIDCD
CEEECHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCEEEEEC
GFTLYVVAASVPWMDGAEIDYVTQSTGNQQLTIKAPKIKGEAPAESASMVERVRWVVENE
CEEEEEEEECCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCC
INPQLASHGGRVAVQEVSAEGVVLLRFGGGCHGCGMADVTLKQGIEKTLMGRVPGVTAVR
CCHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEC
DATDHATGDAPYIPRDSAA
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217