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The map label for this gene is sdhB [H]

Identifier: 21242817

GI number: 21242817

Start: 2426383

End: 2427165

Strand: Direct

Name: sdhB [H]

Synonym: XAC2078

Alternate gene names: 21242817

Gene position: 2426383-2427165 (Clockwise)

Preceding gene: 21242816

Following gene: 21242818

Centisome position: 46.88

GC content: 62.45

Gene sequence:

>783_bases
ATGGCAGAGTTCACCCTCCCCAAGAATTCAAAGATCGGCAAGGGCAAGCATTACCCTGCAAAGGGCGCCAAGAACACGCG
CACCTTCAAGGTCTACCGCTGGGATCCGGACGTCGACGCCAACCCGCGCACCGACAGTTACGAGATCGATCTGGATAAAT
GCGGCCCGATGGTCCTGGACGCGCTGATCAAGATCAAGAACGAGATCGACCCGACGCTGGCGTTCCGTCGCTCCTGCCGC
GAGGGCATCTGCGGCTCGTGCGCGATGAACATCGACGGCACCAATACGCTGGCCTGCACCAAGGCGATTGCCGCGTGCGG
CAAGTCCGAGGTGCCGATCTATCCGCTGCCGCACATGAGCGTGATCAAGGACCTGGTGCCGGACCTGACGCACTTCTATG
CGCAGTACGCGTCGATCAAGCCGTGGATCCGCACCCAGACGCCGCCGCCGCCGGATCGCGAGCGCCTGCAGTCGCCGGAA
GACCGCCGCAAGCTGGATGGCTTGTACGAGTGCATCCTGTGCGCCTGCTGCTCGACCAGCTGCCCGAGCTACTGGTGGAA
TGGCGAGCGGTATCTTGGCCCGGCCATCCTGCTGCAGGCCTACCGCTGGATTATCGATTCGCGCGACGAAGACACCGGTG
CGCGTCTGGACGATCTGGAAGACCCGTTCAAGCTGTATCGCTGCCACACCATCATGAACTGCGCACGGACCTGCCCGAAG
GGCTTGAATCCAGCGCTGGCGATCGCCGAAATCAAGAAGTTGATGATGGCGCGTCGCGCCTGA

Upstream 100 bases:

>100_bases
TGCGCGACTGTTTCGGCAGTGGCATCCGTCATCTTTACCTTCATGCGCACGGTGCGGTTGTCGTCCGCACCGCGCATCGC
CTGAGCCAACGAGAGCAGCT

Downstream 100 bases:

>100_bases
TCGCACGGCATTGATTCCCCGCCACGGGGATGTGGTTCGCAGCGGCACCGGCCCTTGGGTCAGGTGCCGCTGTCGTTTTC
GGACCGCCATGCGGTGCGGT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAEFTLPKNSKIGKGKHYPAKGAKNTRTFKVYRWDPDVDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLAFRRSCR
EGICGSCAMNIDGTNTLACTKAIAACGKSEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPE
DRRKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
GLNPALAIAEIKKLMMARRA

Sequences:

>Translated_260_residues
MAEFTLPKNSKIGKGKHYPAKGAKNTRTFKVYRWDPDVDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLAFRRSCR
EGICGSCAMNIDGTNTLACTKAIAACGKSEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPE
DRRKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
GLNPALAIAEIKKLMMARRA
>Mature_259_residues
AEFTLPKNSKIGKGKHYPAKGAKNTRTFKVYRWDPDVDANPRTDSYEIDLDKCGPMVLDALIKIKNEIDPTLAFRRSCRE
GICGSCAMNIDGTNTLACTKAIAACGKSEVPIYPLPHMSVIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPED
RRKLDGLYECILCACCSTSCPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPKG
LNPALAIAEIKKLMMARRA

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=247, Percent_Identity=65.9919028340081, Blast_Score=347, Evalue=5e-96,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=55.7446808510638, Blast_Score=276, Evalue=9e-76,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.4821428571429, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=237, Percent_Identity=61.6033755274262, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322987, Length=228, Percent_Identity=68.4210526315789, Blast_Score=332, Evalue=4e-92,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=66.5236051502146, Blast_Score=342, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=63.519313304721, Blast_Score=320, Evalue=6e-88,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29396; Mature: 29265

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEFTLPKNSKIGKGKHYPAKGAKNTRTFKVYRWDPDVDANPRTDSYEIDLDKCGPMVLD
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEECHHHCCHHHHH
ALIKIKNEIDPTLAFRRSCREGICGSCAMNIDGTNTLACTKAIAACGKSEVPIYPLPHMS
HHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
VIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPEDRRKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GLNPALAIAEIKKLMMARRA
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEFTLPKNSKIGKGKHYPAKGAKNTRTFKVYRWDPDVDANPRTDSYEIDLDKCGPMVLD
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEECHHHCCHHHHH
ALIKIKNEIDPTLAFRRSCREGICGSCAMNIDGTNTLACTKAIAACGKSEVPIYPLPHMS
HHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
VIKDLVPDLTHFYAQYASIKPWIRTQTPPPPDRERLQSPEDRRKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
CPSYWWNGERYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
GLNPALAIAEIKKLMMARRA
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA