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The map label for this gene is atoS [H]

Identifier: 21242735

GI number: 21242735

Start: 2321861

End: 2323087

Strand: Direct

Name: atoS [H]

Synonym: XAC1991

Alternate gene names: 21242735

Gene position: 2321861-2323087 (Clockwise)

Preceding gene: 21242734

Following gene: 77748625

Centisome position: 44.86

GC content: 61.53

Gene sequence:

>1227_bases
GTGACCGCCAAGTTTTTTCTCAATCAAGCCTTATTGCCGTCCCCGGATATCCTGCGCGCCTTCGGCGACCAGATGATGGA
GGGGCTGCTGCTGTTCCGCGCAGACGGAAAGCTGATTCTGGCCAATGCCATCGCACGCCAGAGCCTGTGCAAGGAAGACC
CCACCGACGATCGCAATCTGGGCGAGCGCATCTCGCAGGTATTGCCATCGGACGCACTCAATCAAGCGCGCAGCAAGGGC
AGCTGGACCGGCAGCCTGCCGGTCGCCGACCGGGTGGTCATTGCGCACCTGTATTACAACGAAGAGTGCGGGCCCGGGCA
TTTTCTGGCGCTGTTCCACAACATCGAAGGCCAGCAGGATTACGAGCGCGAGCTGCAACAGCGCCACGCCGAATTACGCC
AGGCCTATCTGCGCTTGAACGGTGCGCAGGACAAATTGCTGCAATCGGAAAAAATGGCGTCCATCGGCCAGTTGGCCGCA
GGCGTGGCGCACGAAATCAATAATCCGATCGGTTATGTGCACTCCAATTTGGGCAGCCTGCAGGAATATCTGCGCAGCCT
GTTCACCCTGATCGAAGCGTATGAGCGCGCGCTGCAGGCGCCGGACCCCAAGGCGCTGATTCCGGAAATCGACGAGATCC
GCAACCGCGCCGACATCGACTTCATCAGCCGCGATCTGCCGCAACTGATGGCCGAATCGCGCGAAGGCATCGAGCGGGTG
ACCCGCATCGTGCGCGACCTCAAGGACTTCTCGTACTCGGACCGGTCCGAGTCGTGGAAGATGGTCGACCTGCATGCGGG
CCTCGAATCCACCATCAACATCATCTGGAACGAGCTCAAGTACAAGGTCACGCTGGAGCGCAACTACGCCGAGCTGCCGC
TGGTGGAGTGCCTGCCATCCGAGCTCAACCAGGTCTACATGAACATGCTGCTCAATGCCGGCCAGGCCATCGTCGAGCGC
GGCACGATCGCCGTGACCACCGGTCGCGACGAAGCAGAAAACGTCTGGATCCAGTTCCAGGACAGCGGCGCCGGCATTGC
CCCGGATCTGCTGCAGCGCATCTTCGACCCCTTCTTCACCACCAAACCGGTCGGCAGCGGCACCGGCCTGGGTCTGTCGA
TTTCCTACGGCATCATCAACAAGCACCACGGCCGCATCGACGTGGAAAGCACGCCGGGGCAGGGCGCCAGTTTCAGGATC
ACGCTACCGATCCGGCAGCCGCGGTAG

Upstream 100 bases:

>100_bases
GCCGTTCGCTCTGCGACGCGCCGCCGGCTAATGCAAAACGACAATACGGAGCGTCAATGGTTCGGCGTATATTGAGGCAT
CCTCTACGCCGCCTGCTCCC

Downstream 100 bases:

>100_bases
CGCTGACGCGCTGGGAATGGGGAGTTGGGAAATGGGGAATCGGGAATCGGTAAAGCAGCTTTTCGCTCGCTTGATCTGGC
TGCGTGTCTGAGAAGCAACA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTAKFFLNQALLPSPDILRAFGDQMMEGLLLFRADGKLILANAIARQSLCKEDPTDDRNLGERISQVLPSDALNQARSKG
SWTGSLPVADRVVIAHLYYNEECGPGHFLALFHNIEGQQDYERELQQRHAELRQAYLRLNGAQDKLLQSEKMASIGQLAA
GVAHEINNPIGYVHSNLGSLQEYLRSLFTLIEAYERALQAPDPKALIPEIDEIRNRADIDFISRDLPQLMAESREGIERV
TRIVRDLKDFSYSDRSESWKMVDLHAGLESTINIIWNELKYKVTLERNYAELPLVECLPSELNQVYMNMLLNAGQAIVER
GTIAVTTGRDEAENVWIQFQDSGAGIAPDLLQRIFDPFFTTKPVGSGTGLGLSISYGIINKHHGRIDVESTPGQGASFRI
TLPIRQPR

Sequences:

>Translated_408_residues
MTAKFFLNQALLPSPDILRAFGDQMMEGLLLFRADGKLILANAIARQSLCKEDPTDDRNLGERISQVLPSDALNQARSKG
SWTGSLPVADRVVIAHLYYNEECGPGHFLALFHNIEGQQDYERELQQRHAELRQAYLRLNGAQDKLLQSEKMASIGQLAA
GVAHEINNPIGYVHSNLGSLQEYLRSLFTLIEAYERALQAPDPKALIPEIDEIRNRADIDFISRDLPQLMAESREGIERV
TRIVRDLKDFSYSDRSESWKMVDLHAGLESTINIIWNELKYKVTLERNYAELPLVECLPSELNQVYMNMLLNAGQAIVER
GTIAVTTGRDEAENVWIQFQDSGAGIAPDLLQRIFDPFFTTKPVGSGTGLGLSISYGIINKHHGRIDVESTPGQGASFRI
TLPIRQPR
>Mature_407_residues
TAKFFLNQALLPSPDILRAFGDQMMEGLLLFRADGKLILANAIARQSLCKEDPTDDRNLGERISQVLPSDALNQARSKGS
WTGSLPVADRVVIAHLYYNEECGPGHFLALFHNIEGQQDYERELQQRHAELRQAYLRLNGAQDKLLQSEKMASIGQLAAG
VAHEINNPIGYVHSNLGSLQEYLRSLFTLIEAYERALQAPDPKALIPEIDEIRNRADIDFISRDLPQLMAESREGIERVT
RIVRDLKDFSYSDRSESWKMVDLHAGLESTINIIWNELKYKVTLERNYAELPLVECLPSELNQVYMNMLLNAGQAIVERG
TIAVTTGRDEAENVWIQFQDSGAGIAPDLLQRIFDPFFTTKPVGSGTGLGLSISYGIINKHHGRIDVESTPGQGASFRIT
LPIRQPR

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=33.7078651685393, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790436, Length=268, Percent_Identity=33.5820895522388, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790300, Length=282, Percent_Identity=28.7234042553192, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789808, Length=179, Percent_Identity=30.7262569832402, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=107, Percent_Identity=36.4485981308411, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=113, Percent_Identity=36.283185840708, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788393, Length=193, Percent_Identity=26.4248704663212, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45757; Mature: 45625

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAKFFLNQALLPSPDILRAFGDQMMEGLLLFRADGKLILANAIARQSLCKEDPTDDRNL
CCHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHHHCCCCCCCHHH
GERISQVLPSDALNQARSKGSWTGSLPVADRVVIAHLYYNEECGPGHFLALFHNIEGQQD
HHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHEEEEEEEECCCCCCCCEEEEECCCCCCHH
YERELQQRHAELRQAYLRLNGAQDKLLQSEKMASIGQLAAGVAHEINNPIGYVHSNLGSL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QEYLRSLFTLIEAYERALQAPDPKALIPEIDEIRNRADIDFISRDLPQLMAESREGIERV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TRIVRDLKDFSYSDRSESWKMVDLHAGLESTINIIWNELKYKVTLERNYAELPLVECLPS
HHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHH
ELNQVYMNMLLNAGQAIVERGTIAVTTGRDEAENVWIQFQDSGAGIAPDLLQRIFDPFFT
HHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHC
TKPVGSGTGLGLSISYGIINKHHGRIDVESTPGQGASFRITLPIRQPR
CCCCCCCCCCCEEEEECCEECCCCEEEECCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TAKFFLNQALLPSPDILRAFGDQMMEGLLLFRADGKLILANAIARQSLCKEDPTDDRNL
CHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEECCCCEEEHHHHHHHHHHCCCCCCCHHH
GERISQVLPSDALNQARSKGSWTGSLPVADRVVIAHLYYNEECGPGHFLALFHNIEGQQD
HHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHEEEEEEEECCCCCCCCEEEEECCCCCCHH
YERELQQRHAELRQAYLRLNGAQDKLLQSEKMASIGQLAAGVAHEINNPIGYVHSNLGSL
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QEYLRSLFTLIEAYERALQAPDPKALIPEIDEIRNRADIDFISRDLPQLMAESREGIERV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TRIVRDLKDFSYSDRSESWKMVDLHAGLESTINIIWNELKYKVTLERNYAELPLVECLPS
HHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHH
ELNQVYMNMLLNAGQAIVERGTIAVTTGRDEAENVWIQFQDSGAGIAPDLLQRIFDPFFT
HHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHC
TKPVGSGTGLGLSISYGIINKHHGRIDVESTPGQGASFRITLPIRQPR
CCCCCCCCCCCEEEEECCEECCCCEEEECCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]