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The map label for this gene is fnr [H]

Identifier: 21242569

GI number: 21242569

Start: 2120702

End: 2121463

Strand: Reverse

Name: fnr [H]

Synonym: XAC1825

Alternate gene names: 21242569

Gene position: 2121463-2120702 (Counterclockwise)

Preceding gene: 21242581

Following gene: 21242566

Centisome position: 40.99

GC content: 69.69

Gene sequence:

>762_bases
ATGTACCGGCAGCTTTCCGACCCCAGCGCGACCTGCCCGGCGCCCAGCGCGGCATCCGCCAGCGGCACGCCCACCTCAGA
TTGCGCCCTTTGCGCCGTGCGCGGCCGGGCCATTTGTGCGGCGCTCTCGGCGCAGGAAATGGACGCACTGGACCAGGTCA
CCCATGCAGCGGCCTATGCGCCCGGCAGCACCCTGGTACGTGCGGGCGAGACCCGGCACAACGTCTATACCGTGACCTCC
GGCGCGTTGCGCATGGTGCGCACGCTGGCCGACGGACGTCGCCAGATCACCGGCTTCGTGCTGCCCGGCGACTACGTCGG
GCTCACCGAAACCGCGCGGCACCGCCACGATATCGAAGCCATCGTCGACAGCCGGGTGTGCCGCACGCCGATGGCGCACA
TGCGCCAGCTGCGCGAGCGCTACCCGCAGCTGGAACGCAAGCTGCTGCAACGCGCCAGCATGGAACTGGCCGCCGCGCAG
GACACCGGCCTGCTGCTGGCGCGCCTGCAACCCAGCGAACGGCTGGCGCATTTCCTGCTCCGGCTTGCAGCCCGCTCCAC
CCAGCCTGGCGCCAGCGGCGATACCGTGACGCTGCCGATGAGCCGCAGCGACATCGCCGACCACTTGGGGCTGACCGTGG
AAACGGTGAGCCGCACCTTCACCAAGCTGCGGCAGCAGCAGTTGATCGCGCTACCGCAACTGCAGGTGGTGCAGATCCTG
GATTACGCCGCCCTGCGCCGTCTCGCCGGCGATACGGTGTGA

Upstream 100 bases:

>100_bases
ACTCCTGCAGGACAATGTGGCGAACGCACAATTCTAACGGCTGGGCGGCCGCGCTGACCGCATGGCGTATCATTCAATGC
GTCCCAGCAGTGCGTGGCCC

Downstream 100 bases:

>100_bases
GGCTGTTGGGATCGCGTGAGCGCCAGTGTGCGCTTACCCGTGCGACTGGTTGACCGATTGACACGGCGGCGCCCAGTGTC
CAGGCGGTCGATCCGGAACA

Product: fumarate and nitrate reduction regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MYRQLSDPSATCPAPSAASASGTPTSDCALCAVRGRAICAALSAQEMDALDQVTHAAAYAPGSTLVRAGETRHNVYTVTS
GALRMVRTLADGRRQITGFVLPGDYVGLTETARHRHDIEAIVDSRVCRTPMAHMRQLRERYPQLERKLLQRASMELAAAQ
DTGLLLARLQPSERLAHFLLRLAARSTQPGASGDTVTLPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLQVVQIL
DYAALRRLAGDTV

Sequences:

>Translated_253_residues
MYRQLSDPSATCPAPSAASASGTPTSDCALCAVRGRAICAALSAQEMDALDQVTHAAAYAPGSTLVRAGETRHNVYTVTS
GALRMVRTLADGRRQITGFVLPGDYVGLTETARHRHDIEAIVDSRVCRTPMAHMRQLRERYPQLERKLLQRASMELAAAQ
DTGLLLARLQPSERLAHFLLRLAARSTQPGASGDTVTLPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLQVVQIL
DYAALRRLAGDTV
>Mature_253_residues
MYRQLSDPSATCPAPSAASASGTPTSDCALCAVRGRAICAALSAQEMDALDQVTHAAAYAPGSTLVRAGETRHNVYTVTS
GALRMVRTLADGRRQITGFVLPGDYVGLTETARHRHDIEAIVDSRVCRTPMAHMRQLRERYPQLERKLLQRASMELAAAQ
DTGLLLARLQPSERLAHFLLRLAARSTQPGASGDTVTLPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLQVVQIL
DYAALRRLAGDTV

Specific function: B.japonicum has two fixLJ-dependent fixK homologs that are activators of the transcription of a group of genes involved in anaerobic processes such as denitrification and possibly nitrogen fixation. FixK may bind DNA at the FNR consensus binding site [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=235, Percent_Identity=32.7659574468085, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27471; Mature: 27471

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRQLSDPSATCPAPSAASASGTPTSDCALCAVRGRAICAALSAQEMDALDQVTHAAAYA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGSTLVRAGETRHNVYTVTSGALRMVRTLADGRRQITGFVLPGDYVGLTETARHRHDIEA
CCHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHH
IVDSRVCRTPMAHMRQLRERYPQLERKLLQRASMELAAAQDTGLLLARLQPSERLAHFLL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
RLAARSTQPGASGDTVTLPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLQVVQIL
HHHHHCCCCCCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DYAALRRLAGDTV
HHHHHHHHHCCCC
>Mature Secondary Structure
MYRQLSDPSATCPAPSAASASGTPTSDCALCAVRGRAICAALSAQEMDALDQVTHAAAYA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGSTLVRAGETRHNVYTVTSGALRMVRTLADGRRQITGFVLPGDYVGLTETARHRHDIEA
CCHHHEECCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHH
IVDSRVCRTPMAHMRQLRERYPQLERKLLQRASMELAAAQDTGLLLARLQPSERLAHFLL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
RLAARSTQPGASGDTVTLPMSRSDIADHLGLTVETVSRTFTKLRQQQLIALPQLQVVQIL
HHHHHCCCCCCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
DYAALRRLAGDTV
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1551834; 12597275 [H]