Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 21242485

GI number: 21242485

Start: 1994636

End: 1995955

Strand: Direct

Name: hflX [H]

Synonym: XAC1736

Alternate gene names: 21242485

Gene position: 1994636-1995955 (Clockwise)

Preceding gene: 21242484

Following gene: 21242486

Centisome position: 38.54

GC content: 65.83

Gene sequence:

>1320_bases
GTGTTTGATCGGTCCCGCAAGGGTGAACACGCGTTGTTGATACAGACCCACTCCGGCGGGCCTGCCGAAGACGATGTGTT
GGAGGAGTTCGCCGACCTTGCCAAGTCGGCGGGCGCCACGGTGGCGGCCACGCTCACCGCACGCATCGATAAGCCCAGCC
CGTCGACCTTGATCGGTAGCGGCAAGCTGGAAGAGGTCAAGGCCGCAGCCGAGGCCACCGGCGCCGATCTGGTGTTGGTC
AATCACACCCTGTCGCCTGGCCAGGAGCGCAACCTGGAGCGGTATCTGGAGCGGCGTGTGATCGACCGCACCGGGTTGAT
CCTGGACATCTTCGCGCAACGTGCGCGCAGCCACGAAGGCAAGTTGCAGGTGGAACTGGCGCAGTTGCGCCACATGGCCA
CGCGGCTGGTGCGTGGCTGGACGCATTTGGAGCGTCAGCGCGGTGGCTCCATCGGCCTGCGCGGCCCCGGCGAAACCCAG
CTGGAAACCGACCGCCGCCTGCTGCAAAAGCGCGTCGAACAGTTGCAGCAGCGGCTGGAAAAGGTCGAGGTGCAGCGCAC
CCAGATGCGTCGTGCGCGGATGCGCAGCGAACTGCCACGGATTGCACTGGTCGGTTACACCAATGCCGGCAAGTCGACGC
TGTTCAACGTGTTGACCGGTGCAGAGGCTTACGTGGCAGATCAATTGTTCGCCACGCTCGATCCCACCGTGCGACGCATT
GCGTTGCCGGGCGGCAGCGCGATTCTTGCCGACACGGTCGGCTTCGTGCGTGATCTTCCGCACGAGCTGGTCGCCGCGTT
CCGCTCGACGCTGTCGGAGGCGCGCGATGCCGATCTGTTGCTGCACGTTGTCGATGCGGCAGACCCGTTGCGCGAAGAAC
GCATCCTGCAGGTCGACGAAGTGTTGCAGGCCGTCGGTGCCGGCGATCTGCCGCAGCTGCTGGTATTCAACAAGATCGAC
AAGATCGCAGGCGCCGAAGTGCGCCGCGACGCGCAGGACGGCATTCCTGACCCGGCCCGCCGCGAACGTGTGTGGGTATC
GGCGCGCGACGGGCGCGGGCTGGAAGAATTGCAGCATGCGCTCGGCCAGCGGCTGGACCTGCGCCACCTGACCGGCCAGC
TACGGCTACCACCGTCTGCCGGCCGCCTGCGGTCCAGGCTGCATCAGCTGGAAGTGGTGCGCAATGAGCAATCCGACGAA
GAGGGTTGGTTGCTCGAGGTCGATCTGCCGATGGTCGAGGCAGAGCGGTTGGCTGCCGGCGAGGACGGTGCGCCACTGCG
CGCAATGCTGCCGGATCGTCGCGAAGACTGGGAAGCGTGA

Upstream 100 bases:

>100_bases
CGGCGCGCAACGTGCGCGTGGGGCCTGGTGGTGGGTATGTGCAATCCAATGAAGGCAATCAGGCGGAAGATGACGACGTC
GAGCAGTAACGGAGTAGTGC

Downstream 100 bases:

>100_bases
AGAACGCAGCACGCTCGGTATGACGAGAGCGTGCTGCTGCTTCAAGGCGAATGGGGCAGGGTGTACCGCATCGCCGTGCG
GCAGTTGCCAGGCCTCGTCC

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFDRSRKGEHALLIQTHSGGPAEDDVLEEFADLAKSAGATVAATLTARIDKPSPSTLIGSGKLEEVKAAAEATGADLVLV
NHTLSPGQERNLERYLERRVIDRTGLILDIFAQRARSHEGKLQVELAQLRHMATRLVRGWTHLERQRGGSIGLRGPGETQ
LETDRRLLQKRVEQLQQRLEKVEVQRTQMRRARMRSELPRIALVGYTNAGKSTLFNVLTGAEAYVADQLFATLDPTVRRI
ALPGGSAILADTVGFVRDLPHELVAAFRSTLSEARDADLLLHVVDAADPLREERILQVDEVLQAVGAGDLPQLLVFNKID
KIAGAEVRRDAQDGIPDPARRERVWVSARDGRGLEELQHALGQRLDLRHLTGQLRLPPSAGRLRSRLHQLEVVRNEQSDE
EGWLLEVDLPMVEAERLAAGEDGAPLRAMLPDRREDWEA

Sequences:

>Translated_439_residues
MFDRSRKGEHALLIQTHSGGPAEDDVLEEFADLAKSAGATVAATLTARIDKPSPSTLIGSGKLEEVKAAAEATGADLVLV
NHTLSPGQERNLERYLERRVIDRTGLILDIFAQRARSHEGKLQVELAQLRHMATRLVRGWTHLERQRGGSIGLRGPGETQ
LETDRRLLQKRVEQLQQRLEKVEVQRTQMRRARMRSELPRIALVGYTNAGKSTLFNVLTGAEAYVADQLFATLDPTVRRI
ALPGGSAILADTVGFVRDLPHELVAAFRSTLSEARDADLLLHVVDAADPLREERILQVDEVLQAVGAGDLPQLLVFNKID
KIAGAEVRRDAQDGIPDPARRERVWVSARDGRGLEELQHALGQRLDLRHLTGQLRLPPSAGRLRSRLHQLEVVRNEQSDE
EGWLLEVDLPMVEAERLAAGEDGAPLRAMLPDRREDWEA
>Mature_439_residues
MFDRSRKGEHALLIQTHSGGPAEDDVLEEFADLAKSAGATVAATLTARIDKPSPSTLIGSGKLEEVKAAAEATGADLVLV
NHTLSPGQERNLERYLERRVIDRTGLILDIFAQRARSHEGKLQVELAQLRHMATRLVRGWTHLERQRGGSIGLRGPGETQ
LETDRRLLQKRVEQLQQRLEKVEVQRTQMRRARMRSELPRIALVGYTNAGKSTLFNVLTGAEAYVADQLFATLDPTVRRI
ALPGGSAILADTVGFVRDLPHELVAAFRSTLSEARDADLLLHVVDAADPLREERILQVDEVLQAVGAGDLPQLLVFNKID
KIAGAEVRRDAQDGIPDPARRERVWVSARDGRGLEELQHALGQRLDLRHLTGQLRLPPSAGRLRSRLHQLEVVRNEQSDE
EGWLLEVDLPMVEAERLAAGEDGAPLRAMLPDRREDWEA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=233, Percent_Identity=37.3390557939914, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310124269, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124267, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124171, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124169, Length=215, Percent_Identity=38.1395348837209, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310133116, Length=231, Percent_Identity=37.6623376623377, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1790615, Length=424, Percent_Identity=55.6603773584906, Blast_Score=438, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17561038, Length=373, Percent_Identity=31.0991957104558, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24650079, Length=403, Percent_Identity=32.0099255583127, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48756; Mature: 48756

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRSRKGEHALLIQTHSGGPAEDDVLEEFADLAKSAGATVAATLTARIDKPSPSTLIGS
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEECC
GKLEEVKAAAEATGADLVLVNHTLSPGQERNLERYLERRVIDRTGLILDIFAQRARSHEG
CCHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
KLQVELAQLRHMATRLVRGWTHLERQRGGSIGLRGPGETQLETDRRLLQKRVEQLQQRLE
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KVEVQRTQMRRARMRSELPRIALVGYTNAGKSTLFNVLTGAEAYVADQLFATLDPTVRRI
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHEE
ALPGGSAILADTVGFVRDLPHELVAAFRSTLSEARDADLLLHVVDAADPLREERILQVDE
ECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
VLQAVGAGDLPQLLVFNKIDKIAGAEVRRDAQDGIPDPARRERVWVSARDGRGLEELQHA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCEEEEEECCCCCHHHHHHH
LGQRLDLRHLTGQLRLPPSAGRLRSRLHQLEVVRNEQSDEEGWLLEVDLPMVEAERLAAG
HHCCCCHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHCC
EDGAPLRAMLPDRREDWEA
CCCCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MFDRSRKGEHALLIQTHSGGPAEDDVLEEFADLAKSAGATVAATLTARIDKPSPSTLIGS
CCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEECC
GKLEEVKAAAEATGADLVLVNHTLSPGQERNLERYLERRVIDRTGLILDIFAQRARSHEG
CCHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCC
KLQVELAQLRHMATRLVRGWTHLERQRGGSIGLRGPGETQLETDRRLLQKRVEQLQQRLE
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KVEVQRTQMRRARMRSELPRIALVGYTNAGKSTLFNVLTGAEAYVADQLFATLDPTVRRI
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHCHHHHEE
ALPGGSAILADTVGFVRDLPHELVAAFRSTLSEARDADLLLHVVDAADPLREERILQVDE
ECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
VLQAVGAGDLPQLLVFNKIDKIAGAEVRRDAQDGIPDPARRERVWVSARDGRGLEELQHA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCEEEEEECCCCCHHHHHHH
LGQRLDLRHLTGQLRLPPSAGRLRSRLHQLEVVRNEQSDEEGWLLEVDLPMVEAERLAAG
HHCCCCHHHHCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHCC
EDGAPLRAMLPDRREDWEA
CCCCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]