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The map label for this gene is nagZ

Identifier: 21242087

GI number: 21242087

Start: 1540102

End: 1541106

Strand: Direct

Name: nagZ

Synonym: XAC1334

Alternate gene names: 21242087

Gene position: 1540102-1541106 (Clockwise)

Preceding gene: 21242086

Following gene: 21242088

Centisome position: 29.76

GC content: 68.76

Gene sequence:

>1005_bases
ATGCTTCTGATCGGCGTTGCCGGTACCGAACTCAGCGCACAGGAACGCGATTGGCTGCAGCACGATGCGGTTGCCGGCGT
GGTGCTGTTCAAGCGCAACTTCGCCTCGCGCACCCAGGTGGCCGAGCTGTCGGCCGCCATTCGCGCCGCCGCGCCGCGCC
CGGTGCTGATCTGCGTGGACCAGGAAGGTGGGCGCGTGCAGCGGTTTCGCGAAGGATTCAGCGCGCTGGCGCCGTTGCAA
AGCTTCGGTGCGCAATACGCCCAGGACCCGGAGGCTGCACTGGCCGCCGCGCGCGCGCATGCGCAGTTGATGGCCAGCGA
AGTCCGCGCCAGCGGCGTGGACCTGAGCTTTGCGCCGGTGGTGGACCTGGGCCGCGGCAACCGGGCCATTGGCGATCGCG
CCTTCAGCGATGAGCCGCAGATCGTGGCCACCTTCACGCGCGCCTATGTACAGGCGCTGCATGGGGCCGGCATGGCCGCC
ACGCTCAAGCATTTCCCCGGCCACGGCACCGTGCTGGAAGACACCCATGTCGACCACGCCAGCGACCCGCGGCCGCTGGA
GGTGCTGCAGGCCGAAGACCTGGTGCCGTTCGTGGCGGGGATCGAGGCCGGCGCCGACGCCGTGATGATGGCGCACGTGG
TCTACCCGCAGGTCGCCCCGGAGCCGGCCGGCTATTCGCAGCGCTGGATCGAGCAGATCCTGCGCGGCCAGATGGGCTTC
CGCGGCGTGGTCTTTTCCGACGACATCGGCATGGCCGCCTCGTTCAGTGCCGGCGGGGTGGCGGGTCGTGTGCATGCGCA
TCTGGATGCCGGCTGCGACGTGGTGCTGGTGTGCCACCCGGAACTGGTCGCCGAATCGCTGCAGGCCGTGCAGGGCCGCA
GCCTCAATACCGCCGCATTGATCGGCCTGATCGGCCGCGGCGCACTAGGTTGGGATGGCCTGCTCGCCGGCACCGATGCC
TCATTTACCACTCCTCTTTCTGCCCATTTCGGAACAACTGCCTGA

Upstream 100 bases:

>100_bases
GCAGGGGCGCGCAGCTGAATGCGCGATCTGACGCTGCCACGCGCATCTGCGACAATGCCGCGCTGCGCCACCATGGCGCC
TGGCCCGGGAGTCCCCCAAC

Downstream 100 bases:

>100_bases
TGTCCACGCTCACCATTTCCCAGGCCCTGGCCCAAGCCGATCTGCTGGTCGACCGTCCGGCCATCGATGCCGCCGTTGCC
ACCATCGCCGATGCGATCGC

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFASRTQVAELSAAIRAAAPRPVLICVDQEGGRVQRFREGFSALAPLQ
SFGAQYAQDPEAALAAARAHAQLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDEPQIVATFTRAYVQALHGAGMAA
TLKHFPGHGTVLEDTHVDHASDPRPLEVLQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGF
RGVVFSDDIGMAASFSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRSLNTAALIGLIGRGALGWDGLLAGTDA
SFTTPLSAHFGTTA

Sequences:

>Translated_334_residues
MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFASRTQVAELSAAIRAAAPRPVLICVDQEGGRVQRFREGFSALAPLQ
SFGAQYAQDPEAALAAARAHAQLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDEPQIVATFTRAYVQALHGAGMAA
TLKHFPGHGTVLEDTHVDHASDPRPLEVLQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGF
RGVVFSDDIGMAASFSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRSLNTAALIGLIGRGALGWDGLLAGTDA
SFTTPLSAHFGTTA
>Mature_334_residues
MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFASRTQVAELSAAIRAAAPRPVLICVDQEGGRVQRFREGFSALAPLQ
SFGAQYAQDPEAALAAARAHAQLMASEVRASGVDLSFAPVVDLGRGNRAIGDRAFSDEPQIVATFTRAYVQALHGAGMAA
TLKHFPGHGTVLEDTHVDHASDPRPLEVLQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGF
RGVVFSDDIGMAASFSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRSLNTAALIGLIGRGALGWDGLLAGTDA
SFTTPLSAHFGTTA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=279, Percent_Identity=44.8028673835125, Blast_Score=237, Evalue=8e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_XANAC (Q8PMU1)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641669.1
- ProteinModelPortal:   Q8PMU1
- SMR:   Q8PMU1
- GeneID:   1155405
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1334
- NMPDR:   fig|190486.1.peg.1313
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- ProtClustDB:   PRK05337
- BioCyc:   XAXO190486:XAC1334-MONOMER
- BRENDA:   3.2.1.52
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 35003; Mature: 35003

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 247-247

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFASRTQVAELSAAIRAAAPRPVLICVD
CEEEEECCCCCCHHHHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHHHCCCCCEEEEEE
QEGGRVQRFREGFSALAPLQSFGAQYAQDPEAALAAARAHAQLMASEVRASGVDLSFAPV
CCCCHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
VDLGRGNRAIGDRAFSDEPQIVATFTRAYVQALHGAGMAATLKHFPGHGTVLEDTHVDHA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCC
SDPRPLEVLQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGF
CCCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCC
RGVVFSDDIGMAASFSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRSLNTAAL
CEEEEECCCCCEECCCCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHCCCCCCHHHH
IGLIGRGALGWDGLLAGTDASFTTPLSAHFGTTA
HHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLIGVAGTELSAQERDWLQHDAVAGVVLFKRNFASRTQVAELSAAIRAAAPRPVLICVD
CEEEEECCCCCCHHHHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHHHCCCCCEEEEEE
QEGGRVQRFREGFSALAPLQSFGAQYAQDPEAALAAARAHAQLMASEVRASGVDLSFAPV
CCCCHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCE
VDLGRGNRAIGDRAFSDEPQIVATFTRAYVQALHGAGMAATLKHFPGHGTVLEDTHVDHA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCC
SDPRPLEVLQAEDLVPFVAGIEAGADAVMMAHVVYPQVAPEPAGYSQRWIEQILRGQMGF
CCCCCHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCC
RGVVFSDDIGMAASFSAGGVAGRVHAHLDAGCDVVLVCHPELVAESLQAVQGRSLNTAAL
CEEEEECCCCCEECCCCCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHCCCCCCHHHH
IGLIGRGALGWDGLLAGTDASFTTPLSAHFGTTA
HHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217