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The map label for this gene is hrpG [H]

Identifier: 21242018

GI number: 21242018

Start: 1444841

End: 1445632

Strand: Reverse

Name: hrpG [H]

Synonym: XAC1265

Alternate gene names: 21242018

Gene position: 1445632-1444841 (Counterclockwise)

Preceding gene: 77748573

Following gene: 21242005

Centisome position: 27.93

GC content: 61.11

Gene sequence:

>792_bases
ATGAACGACCACTCTCCCCCCAACGCCGGATCGGTGTTCCTGTTGACGCAGGATGCGCGCCTGGTCTCGCAGGTCAACGC
CAGCCTCGCACCGCTTGCGCGCAATGTCTCGACGTTTTCCGATGAACTGGAGCTTTTGCGTACGCTGCGGCATTCGCCGT
GCGAGCTGCTGATCTTCGATGCCAGCTATGTCGCCGCCGATGACAGTTCACTGCTGGCATGGCAGCGCTGCCATAGCGGC
CAGCCCACCCCGTTGATCGTGCTTGGACGTTTCGATTGCGCAGACAACATTCTGGCCTGGTATCGCGCAGGCGCGCAGGA
AGTCCTTGCGCTGCCTTTCAATTCGCACGAGTTACACGTGCGCGCGGCGCTGGCGATATCGCCGGTGGCGCATGCCTGCC
CGGAGACGCAGCACCTGAGCGTTGGTCCATACCGGTTGATCCGCGATGAAAATACCGTTTATCTGGACGGCAAGCCGATC
GTATTGACCGCACGCGAGTTCTCGATTGCCTGGCTGCTCTTTTCCAGCCCCGGCGTGTGTTTCCGGCGTTGCCAACTGGC
CAAGGCCGTCTGGGGCAGCCACACCGAATTCACCGACCGCACCATGGAGCAGCACATCTACAAGTTGCGCAAGAAACTGC
AGCTGAGCAGTGACAGCAGCGCAGTGCGCATCAGAACCGTCTATTCGCACGGCTACAAGTTGGAGCTCGCGCTGCACGAT
ACGGAGGCAACGACAATGAGCAAGGCCGTGAGCCCAAGCCTTGGCCCTGCACATCACGCAGCCGCCTGCTGA

Upstream 100 bases:

>100_bases
GCAGCGATCTTTGAAGATGGATTTTGTCCTGGCATTGGCCGACCAGCACCGGCGCCCGCCCCATGCGTGGCTTCTACGCC
GACACGCGAAGGCCGCCTAA

Downstream 100 bases:

>100_bases
GCAAGCGCACCGCTGCCGATCTGCGATCTGCATTGCGCACTCTCGCTTGCGTTAAAGCGAAGGGTGTTTGATGACACGAT
GAGCGTCGGCACGCTCTCAA

Product: HrpG protein

Products: NA

Alternate protein names: Staphylococcal respiratory response protein A [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNDHSPPNAGSVFLLTQDARLVSQVNASLAPLARNVSTFSDELELLRTLRHSPCELLIFDASYVAADDSSLLAWQRCHSG
QPTPLIVLGRFDCADNILAWYRAGAQEVLALPFNSHELHVRAALAISPVAHACPETQHLSVGPYRLIRDENTVYLDGKPI
VLTAREFSIAWLLFSSPGVCFRRCQLAKAVWGSHTEFTDRTMEQHIYKLRKKLQLSSDSSAVRIRTVYSHGYKLELALHD
TEATTMSKAVSPSLGPAHHAAAC

Sequences:

>Translated_263_residues
MNDHSPPNAGSVFLLTQDARLVSQVNASLAPLARNVSTFSDELELLRTLRHSPCELLIFDASYVAADDSSLLAWQRCHSG
QPTPLIVLGRFDCADNILAWYRAGAQEVLALPFNSHELHVRAALAISPVAHACPETQHLSVGPYRLIRDENTVYLDGKPI
VLTAREFSIAWLLFSSPGVCFRRCQLAKAVWGSHTEFTDRTMEQHIYKLRKKLQLSSDSSAVRIRTVYSHGYKLELALHD
TEATTMSKAVSPSLGPAHHAAAC
>Mature_263_residues
MNDHSPPNAGSVFLLTQDARLVSQVNASLAPLARNVSTFSDELELLRTLRHSPCELLIFDASYVAADDSSLLAWQRCHSG
QPTPLIVLGRFDCADNILAWYRAGAQEVLALPFNSHELHVRAALAISPVAHACPETQHLSVGPYRLIRDENTVYLDGKPI
VLTAREFSIAWLLFSSPGVCFRRCQLAKAVWGSHTEFTDRTMEQHIYKLRKKLQLSSDSSAVRIRTVYSHGYKLELALHD
TEATTMSKAVSPSLGPAHHAAAC

Specific function: Member of the two-component regulatory system srrA/srrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels. SrrA binds to the agr, spa and tst promoters and represses their transcript

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=26.2222222222222, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788394, Length=194, Percent_Identity=28.8659793814433, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87082012, Length=204, Percent_Identity=27.4509803921569, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29042; Mature: 29042

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDHSPPNAGSVFLLTQDARLVSQVNASLAPLARNVSTFSDELELLRTLRHSPCELLIFD
CCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ASYVAADDSSLLAWQRCHSGQPTPLIVLGRFDCADNILAWYRAGAQEVLALPFNSHELHV
CEEEECCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCEEEE
RAALAISPVAHACPETQHLSVGPYRLIRDENTVYLDGKPIVLTAREFSIAWLLFSSPGVC
EEEEEECHHHHHCCCCCCCCCCCEEEEECCCEEEECCCEEEEEECCEEEEEEEECCCCHH
FRRCQLAKAVWGSHTEFTDRTMEQHIYKLRKKLQLSSDSSAVRIRTVYSHGYKLELALHD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEEEC
TEATTMSKAVSPSLGPAHHAAAC
CCHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDHSPPNAGSVFLLTQDARLVSQVNASLAPLARNVSTFSDELELLRTLRHSPCELLIFD
CCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ASYVAADDSSLLAWQRCHSGQPTPLIVLGRFDCADNILAWYRAGAQEVLALPFNSHELHV
CEEEECCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCEEEE
RAALAISPVAHACPETQHLSVGPYRLIRDENTVYLDGKPIVLTAREFSIAWLLFSSPGVC
EEEEEECHHHHHCCCCCCCCCCCEEEEECCCEEEECCCEEEEEECCEEEEEEEECCCCHH
FRRCQLAKAVWGSHTEFTDRTMEQHIYKLRKKLQLSSDSSAVRIRTVYSHGYKLELALHD
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEEEC
TEATTMSKAVSPSLGPAHHAAAC
CCHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA