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The map label for this gene is minC

Identifier: 21241980

GI number: 21241980

Start: 1404902

End: 1405651

Strand: Reverse

Name: minC

Synonym: XAC1226

Alternate gene names: 21241980

Gene position: 1405651-1404902 (Counterclockwise)

Preceding gene: 77748571

Following gene: 21241979

Centisome position: 27.16

GC content: 68.27

Gene sequence:

>750_bases
GTGGCAAGTGTGAATGTGGATTTTGAACAGGCCGGCGAGCTGAAGATCGGCCAAGTAGGGATTGCCAACCTGCGCGTGCG
CACCCTGGATGTGTCGCGGCTGGTGCAGGAAATGCGCGAGCGCGTGACCCGCGCGCCCAAGTTGTTCGGCCGTGCGGCGG
TGATCCTGGATTTCGGCGGGCTGTCGCAGGTGCCGGACCTGGCCACGGCCAAGGCCCTGCTGGAAGGTCTGCGCGATGCC
GGCGTGCTGCCGGTGGCGCTGGCCTACGGCACCAGCGAGATCGACCTGCTGTCCCAGCAGTTGGGCGTGCCGCTGCTGGC
CAAATTTCGCGCGCAGTACGAGCCGACCGCGGTCAGCCCGCCACCGCCACCGCCACCGCCGCCCGCACGTGCCGAACCGG
CACCGCCGGCCGCGCGACCGGCTCCGGGCCGGATGCAGCGCACCGCGGTGCGTTCCGGTCAGCAGCTGTACGCGGAGAAC
TGCGACCTGACCGTACTCAGTACGGTCGGTGCCGGGGCCGAGGTCATCGCCGACGGCAGCATCCATATCTACGGTACCCT
GCGTGGCCGCGCTCTGGCCGGCGCGCAGGGCAACCCCGACGCGCGCATCTTCTGCCGCGACTTCCACGCCGAACTGGTTG
CCATCGCTGGCCACTACAAGGTGCTGGACGATGTTCCCATGGACCTGCGTGGCAAGGCCGTCCAGGTCTGGCTGGAGCAG
GATCAGATCAAGATCGCTGCGCTTGATTGA

Upstream 100 bases:

>100_bases
CAAAGAGACCTATGGCGGCAAGTTGCCCGAAGACTTGCCGTGGGTGGGCCGGCCGCGTCATGCCGCCACCACCGCTAGCC
CATCGACGGGGAGCTGAGTT

Downstream 100 bases:

>100_bases
CGCGGCCCAACCACAGAAATATTCGGAGAAATCCTTTGGCTGAAATCATCGTAGTCACCTCCGGCAAGGGCGGCGTCGGC
AAGACCACCACCAGCGCAAG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MASVNVDFEQAGELKIGQVGIANLRVRTLDVSRLVQEMRERVTRAPKLFGRAAVILDFGGLSQVPDLATAKALLEGLRDA
GVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAEN
CDLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQ
DQIKIAALD

Sequences:

>Translated_249_residues
MASVNVDFEQAGELKIGQVGIANLRVRTLDVSRLVQEMRERVTRAPKLFGRAAVILDFGGLSQVPDLATAKALLEGLRDA
GVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAEN
CDLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQ
DQIKIAALD
>Mature_248_residues
ASVNVDFEQAGELKIGQVGIANLRVRTLDVSRLVQEMRERVTRAPKLFGRAAVILDFGGLSQVPDLATAKALLEGLRDAG
VLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENC
DLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQD
QIKIAALD

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=239, Percent_Identity=35.9832635983264, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_XANAC (Q8PN47)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641562.1
- ProteinModelPortal:   Q8PN47
- GeneID:   1155297
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1226
- NMPDR:   fig|190486.1.peg.1206
- HOGENOM:   HBG399077
- OMA:   ARIFCRD
- ProtClustDB:   PRK04596
- BioCyc:   XAXO190486:XAC1226-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 26521; Mature: 26390

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVNVDFEQAGELKIGQVGIANLRVRTLDVSRLVQEMRERVTRAPKLFGRAAVILDFGG
CCCCCCCHHHCCCEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
LSQVPDLATAKALLEGLRDAGVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSP
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
PPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCDLTVLSTVGAGAEVIADGS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCEEEECCC
IHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQ
EEEEEEECCEEEECCCCCCCCEEEEEEHHHEEEHHHCCEEEECCCCCCCCCCEEEEEEEC
DQIKIAALD
CCEEEEEEC
>Mature Secondary Structure 
ASVNVDFEQAGELKIGQVGIANLRVRTLDVSRLVQEMRERVTRAPKLFGRAAVILDFGG
CCCCCCHHHCCCEEECCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
LSQVPDLATAKALLEGLRDAGVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSP
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
PPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCDLTVLSTVGAGAEVIADGS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCEEEECCC
IHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQ
EEEEEEECCEEEECCCCCCCCEEEEEEHHHEEEHHHCCEEEECCCCCCCCCCEEEEEEEC
DQIKIAALD
CCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217