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The map label for this gene is pilH [H]

Identifier: 21241908

GI number: 21241908

Start: 1313897

End: 1314283

Strand: Direct

Name: pilH [H]

Synonym: XAC1154

Alternate gene names: 21241908

Gene position: 1313897-1314283 (Clockwise)

Preceding gene: 21241906

Following gene: 21241909

Centisome position: 25.39

GC content: 62.02

Gene sequence:

>387_bases
ATGGCACGTATTTTGATCGTCGACGACTCGCCGTCGCAGCTGCTGGGGATTCAGCGCATCGTCGAGAAGCTGGGGCACGA
AACCATCACCGCCACCGATGGTGCCGCCGGCGTGGAAGCGGCCAAGCAATCGCTGCCGGATCTGGTGCTGATGGACGTGG
TGATGCCCAACCTCAACGGATTCCAGGCCACGCGCACGCTCAAGCGCGAGCCCACCACCCAGCATATTCCGGTCATCCTG
GTCACCACCAAGGATCAGGACACCGACCGCATGTGGGGCATGCGCCAGGGGGCCCGCGCCTACATCACCAAGCCGTTCTC
CGAAGACGAGCTGCTGGAAGTGATGGAGCGTGTGTTCAACCAGAAAGAAGAGCCGCCGAAAGCGTAA

Upstream 100 bases:

>100_bases
GCCACGCTCGCCGACCACGAACCCTCCAGCAACTCACCTGGCCCAGCTACCGAAAGCGCGGCCGGCGCACTACACTCGCC
GCGCACACTAGGGGAAACAC

Downstream 100 bases:

>100_bases
GTGCACCGGCCAGGCGTGATCGACGTCGGATTTCGGCAACGCAGATGTGGGATTAGCGGTAGACGGTCCAACCCTCTCCC
GCGGGAGGGAGTCCGATGAG

Product: PilH family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MARILIVDDSPSQLLGIQRIVEKLGHETITATDGAAGVEAAKQSLPDLVLMDVVMPNLNGFQATRTLKREPTTQHIPVIL
VTTKDQDTDRMWGMRQGARAYITKPFSEDELLEVMERVFNQKEEPPKA

Sequences:

>Translated_128_residues
MARILIVDDSPSQLLGIQRIVEKLGHETITATDGAAGVEAAKQSLPDLVLMDVVMPNLNGFQATRTLKREPTTQHIPVIL
VTTKDQDTDRMWGMRQGARAYITKPFSEDELLEVMERVFNQKEEPPKA
>Mature_127_residues
ARILIVDDSPSQLLGIQRIVEKLGHETITATDGAAGVEAAKQSLPDLVLMDVVMPNLNGFQATRTLKREPTTQHIPVILV
TTKDQDTDRMWGMRQGARAYITKPFSEDELLEVMERVFNQKEEPPKA

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=36.6666666666667, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1788394, Length=128, Percent_Identity=32.8125, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI87082012, Length=110, Percent_Identity=30.9090909090909, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790863, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=117, Percent_Identity=34.1880341880342, Blast_Score=63, Evalue=5e-12,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=114, Percent_Identity=31.5789473684211, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=30.327868852459, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 14314; Mature: 14182

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILIVDDSPSQLLGIQRIVEKLGHETITATDGAAGVEAAKQSLPDLVLMDVVMPNLNG
CEEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
FQATRTLKREPTTQHIPVILVTTKDQDTDRMWGMRQGARAYITKPFSEDELLEVMERVFN
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHC
QKEEPPKA
CCCCCCCC
>Mature Secondary Structure 
ARILIVDDSPSQLLGIQRIVEKLGHETITATDGAAGVEAAKQSLPDLVLMDVVMPNLNG
EEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
FQATRTLKREPTTQHIPVILVTTKDQDTDRMWGMRQGARAYITKPFSEDELLEVMERVFN
HHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHC
QKEEPPKA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]