Click here to switch to the map view.

The map label for this gene is rihA [H]

Identifier: 21241898

GI number: 21241898

Start: 1296285

End: 1297175

Strand: Direct

Name: rihA [H]

Synonym: XAC1144

Alternate gene names: 21241898

Gene position: 1296285-1297175 (Clockwise)

Preceding gene: 77748560

Following gene: 21241899

Centisome position: 25.05

GC content: 66.22

Gene sequence:

>891_bases
GTGCAGACCGAGAAAGTGGTGGTCTCCACCGACATCGGCGACGATATCGACGATGCGTTCGCGTTGGGATTGCTGCTGCG
TCGTCCGCAGTTGCAGGTGCTGGGCATCGCATCGGCATGGGGCGACACCACGTTGCGCGTGCAGTTGCTGCAGCGGTTGT
TGCAGCAGGCCGGGCGCAGCGAGATCCCGCTGGCGGTGGGCGCGCGTACCACCAGCAGCATTGCGTTTAGCCAGGCAGGC
TGGGCGGCCAAGGGACAGGTACCGGCGGCACTGCCTGATGCGGCTGCGATGATCCTGCAGCAGGCGCGCCAGCATCCGGG
CGAGGTCACCTTGCTGGTGCTGGGGCCGATGACCGATGCGGCGCTGGCGCAACAACGCGACCCGGCCGGCTTTGCCAAGC
TCAAGCGTGTGGTGGCGATGGGCGGATCTGTGCGGGTGGGCTATGGCAAGTCTGCGTATCGTCCGGCCAGTACGCCGGTG
CCGGAGTACAACATCCTGGCCGACGTGCCGGCAGCGCAGCGCGTGTTCTCATCTGGTGTGCCGATCGTGTTGTTGCCGCT
GGATGCCACGCAGATCACGCTGGAAGAGCCCGAGCGCGTGGCCTTGTTCGCGCACGGTGACGGACTGACCGATGCGCTGA
CGCAGCTGTACTACCAGTGGCGCAACACCGACCAGCCCTGGGCCAGTGCCACGCCCACATTGTTCGATGTAGTGCCGGTG
GCCTGGCTGCTACGCCCGGCGCTGTGCCCGACCACGCCGCTGCATCTGGACGTGGATGCGCAAGGCTATACCCGCGAAGG
CGCTGGTGCGCCCAATGTGCAGGCCTGTCTGCGCGTGGATAAGCCGGCGCTGATCGAACTGTACATGCGTGCGTTGCTGG
AGTTGCCCTGA

Upstream 100 bases:

>100_bases
GACCTGGCAGCGCGCGTGGGGATTGGTAGCGATGTGGTGCGTGTCCACTGCCGCGTGGGCGCAGCAGTCCGCCGCGGCCG
TGCCATCCATGCCGGCATCG

Downstream 100 bases:

>100_bases
TAGCGGGGAACAAATGTCGTCAATGCCTGTGCCCCGCGGCGAGTGCTTTTTTTGCAGCTCTTTGTGAGCTAGTCAAAAGC
CTGGTTGGTCGACAGCGCGA

Product: inosine-uridine preferring nucleoside hydrolase

Products: uracil; ribose; cytosine [C]

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQTEKVVVSTDIGDDIDDAFALGLLLRRPQLQVLGIASAWGDTTLRVQLLQRLLQQAGRSEIPLAVGARTTSSIAFSQAG
WAAKGQVPAALPDAAAMILQQARQHPGEVTLLVLGPMTDAALAQQRDPAGFAKLKRVVAMGGSVRVGYGKSAYRPASTPV
PEYNILADVPAAQRVFSSGVPIVLLPLDATQITLEEPERVALFAHGDGLTDALTQLYYQWRNTDQPWASATPTLFDVVPV
AWLLRPALCPTTPLHLDVDAQGYTREGAGAPNVQACLRVDKPALIELYMRALLELP

Sequences:

>Translated_296_residues
MQTEKVVVSTDIGDDIDDAFALGLLLRRPQLQVLGIASAWGDTTLRVQLLQRLLQQAGRSEIPLAVGARTTSSIAFSQAG
WAAKGQVPAALPDAAAMILQQARQHPGEVTLLVLGPMTDAALAQQRDPAGFAKLKRVVAMGGSVRVGYGKSAYRPASTPV
PEYNILADVPAAQRVFSSGVPIVLLPLDATQITLEEPERVALFAHGDGLTDALTQLYYQWRNTDQPWASATPTLFDVVPV
AWLLRPALCPTTPLHLDVDAQGYTREGAGAPNVQACLRVDKPALIELYMRALLELP
>Mature_296_residues
MQTEKVVVSTDIGDDIDDAFALGLLLRRPQLQVLGIASAWGDTTLRVQLLQRLLQQAGRSEIPLAVGARTTSSIAFSQAG
WAAKGQVPAALPDAAAMILQQARQHPGEVTLLVLGPMTDAALAQQRDPAGFAKLKRVVAMGGSVRVGYGKSAYRPASTPV
PEYNILADVPAAQRVFSSGVPIVLLPLDATQITLEEPERVALFAHGDGLTDALTQLYYQWRNTDQPWASATPTLFDVVPV
AWLLRPALCPTTPLHLDVDAQGYTREGAGAPNVQACLRVDKPALIELYMRALLELP

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=299, Percent_Identity=29.0969899665552, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788486, Length=275, Percent_Identity=25.8181818181818, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786213, Length=244, Percent_Identity=29.5081967213115, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: NA

Molecular weight: Translated: 31744; Mature: 31744

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTEKVVVSTDIGDDIDDAFALGLLLRRPQLQVLGIASAWGDTTLRVQLLQRLLQQAGRS
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
EIPLAVGARTTSSIAFSQAGWAAKGQVPAALPDAAAMILQQARQHPGEVTLLVLGPMTDA
CCCEEECCCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHH
ALAQQRDPAGFAKLKRVVAMGGSVRVGYGKSAYRPASTPVPEYNILADVPAAQRVFSSGV
HHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEECCCHHHHHHHCCC
PIVLLPLDATQITLEEPERVALFAHGDGLTDALTQLYYQWRNTDQPWASATPTLFDVVPV
CEEEEECCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AWLLRPALCPTTPLHLDVDAQGYTREGAGAPNVQACLRVDKPALIELYMRALLELP
HHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQTEKVVVSTDIGDDIDDAFALGLLLRRPQLQVLGIASAWGDTTLRVQLLQRLLQQAGRS
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
EIPLAVGARTTSSIAFSQAGWAAKGQVPAALPDAAAMILQQARQHPGEVTLLVLGPMTDA
CCCEEECCCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHH
ALAQQRDPAGFAKLKRVVAMGGSVRVGYGKSAYRPASTPVPEYNILADVPAAQRVFSSGV
HHHHCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCEEECCCHHHHHHHCCC
PIVLLPLDATQITLEEPERVALFAHGDGLTDALTQLYYQWRNTDQPWASATPTLFDVVPV
CEEEEECCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
AWLLRPALCPTTPLHLDVDAQGYTREGAGAPNVQACLRVDKPALIELYMRALLELP
HHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uridine; H2O; cytidine [C]

Specific reaction: uridine + H2O = uracil + ribose cytidine + H2O = cytosine + ribose [C]

General reaction: Pyrimidine-specific nucleoside hydrolase [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA