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The map label for this gene is prpC [H]

Identifier: 21241848

GI number: 21241848

Start: 1245381

End: 1246085

Strand: Reverse

Name: prpC [H]

Synonym: XAC1091

Alternate gene names: 21241848

Gene position: 1246085-1245381 (Counterclockwise)

Preceding gene: 21241850

Following gene: 21241844

Centisome position: 24.08

GC content: 66.24

Gene sequence:

>705_bases
ATGCTCGAATTCGGACACCTCACCCATGTCGGCCTGCGCCGTGACCTCAACGAGGACACCTATTACGGCGACAGCGAGCT
GGGATTGTGGCTGGTCGCCGACGGCATGGGGGGGCATGCCTGCGGGGAAGTAGCCAGCGCATTGGCGCGCGAAACCATCG
TGCGAGAAGTTCGCGCCGGGACCCCGCTCGCCCAGGCGGTACGCATCGCCGACGAAGAGATCATCAAGACCTCGCGCCGC
TGCAACGACACCCTGCCGATGGGCACCACCGTGGTCGCCGCGCGCGTACTCGGCCAGCGTTTCGAAGTGGCCTGGGTTGG
CGACAGCCGCGCCTACCTGTGGCGCGATGGCCGGCTGGCGCAGCTGAGCCAGGACCACAGCTATGTGCAGGAGCTCATCG
CCCAAGGCACGCTGACCAGCGAGCAGGCACGCGCGCACCCGCATCGCAACGTGGTGACCCAGGCACTCGGCGTGACCGAC
CCGGCGCACCTGAATGTCGCCATCATGCAAGGCGAACTCAAATCCGGCATGCAGCTATTGCTGTGCAGCGACGGCCTGAC
CGAAGAGGTGGACGATGCCGCCATCGCAGCCACGTTGTCGCAGGCCGATTGCAGCGCGCAGGAATGCGTGGAATGCCTGG
TCGCCGCCGCACTGGATGGCGGCGGTTCGGACAACATCACCGCGATCCTGGTGCGCAGTTACTGA

Upstream 100 bases:

>100_bases
AGGCGTGAACCGGTGCTGCGACGCCCGCGCGCGGCGTGTTGCCGCTAACCGGCCGGGCCGCGATGATGGTGGTGCATCTT
CTTCTTGGCGACCCGGCCCC

Downstream 100 bases:

>100_bases
GCGCTGCGCGCAAGCGGACAGTTGCGCAACAAAGCGCAGCGACCGCCAGCCATCGTTCAATCCCCATGTGGCCGCTTGGT
TTCTGCGACGAAACGTCGCC

Product: protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLEFGHLTHVGLRRDLNEDTYYGDSELGLWLVADGMGGHACGEVASALARETIVREVRAGTPLAQAVRIADEEIIKTSRR
CNDTLPMGTTVVAARVLGQRFEVAWVGDSRAYLWRDGRLAQLSQDHSYVQELIAQGTLTSEQARAHPHRNVVTQALGVTD
PAHLNVAIMQGELKSGMQLLLCSDGLTEEVDDAAIAATLSQADCSAQECVECLVAAALDGGGSDNITAILVRSY

Sequences:

>Translated_234_residues
MLEFGHLTHVGLRRDLNEDTYYGDSELGLWLVADGMGGHACGEVASALARETIVREVRAGTPLAQAVRIADEEIIKTSRR
CNDTLPMGTTVVAARVLGQRFEVAWVGDSRAYLWRDGRLAQLSQDHSYVQELIAQGTLTSEQARAHPHRNVVTQALGVTD
PAHLNVAIMQGELKSGMQLLLCSDGLTEEVDDAAIAATLSQADCSAQECVECLVAAALDGGGSDNITAILVRSY
>Mature_234_residues
MLEFGHLTHVGLRRDLNEDTYYGDSELGLWLVADGMGGHACGEVASALARETIVREVRAGTPLAQAVRIADEEIIKTSRR
CNDTLPMGTTVVAARVLGQRFEVAWVGDSRAYLWRDGRLAQLSQDHSYVQELIAQGTLTSEQARAHPHRNVVTQALGVTD
PAHLNVAIMQGELKSGMQLLLCSDGLTEEVDDAAIAATLSQADCSAQECVECLVAAALDGGGSDNITAILVRSY

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 25117; Mature: 25117

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFGHLTHVGLRRDLNEDTYYGDSELGLWLVADGMGGHACGEVASALARETIVREVRAG
CCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
TPLAQAVRIADEEIIKTSRRCNDTLPMGTTVVAARVLGQRFEVAWVGDSRAYLWRDGRLA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEECCCCEEEEECCCHH
QLSQDHSYVQELIAQGTLTSEQARAHPHRNVVTQALGVTDPAHLNVAIMQGELKSGMQLL
HHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECHHHCCCEEE
LCSDGLTEEVDDAAIAATLSQADCSAQECVECLVAAALDGGGSDNITAILVRSY
EECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure
MLEFGHLTHVGLRRDLNEDTYYGDSELGLWLVADGMGGHACGEVASALARETIVREVRAG
CCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
TPLAQAVRIADEEIIKTSRRCNDTLPMGTTVVAARVLGQRFEVAWVGDSRAYLWRDGRLA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEECCCCEEEEECCCHH
QLSQDHSYVQELIAQGTLTSEQARAHPHRNVVTQALGVTDPAHLNVAIMQGELKSGMQLL
HHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEEEECHHHCCCEEE
LCSDGLTEEVDDAAIAATLSQADCSAQECVECLVAAALDGGGSDNITAILVRSY
EECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]