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The map label for this gene is gst [H]

Identifier: 21241772

GI number: 21241772

Start: 1161941

End: 1162585

Strand: Reverse

Name: gst [H]

Synonym: XAC1007

Alternate gene names: 21241772

Gene position: 1162585-1161941 (Counterclockwise)

Preceding gene: 21241773

Following gene: 21241769

Centisome position: 22.46

GC content: 62.02

Gene sequence:

>645_bases
ATGAAGCTGTATACCAAGCCCGGCGCTTGTTCGCTGGCAGATCACATCGTGTTGCGTTGGTCGGGGCTGCCGTTCGACCT
GAGTGTGGTCGATGCGGCGACGATGAAATCTCCCGAGTACCTGCGTCTGAATCCAGCAGGCGCCGTGCCATTGCTGCTGG
TCGACGATTGGGCACTGACCCAGAATGCAGCCATCCTCAATTACATCGCCGACATCGCGCCGCTCACCGGCCTATCCGGC
GATGGCACCGCGCGCAGCCGTGCCGAAATCAATCGTTGGATCGCCTTCGTCAATGCCGACGTGCACCCCACCTTCAAGCC
GATCTTCGGCAGCACCGCGTATCTGCAAGACCCGGCGCTGATTGCGCGCAGCCAGGACGATGCGCGCGTCAAATTGCGCA
CGCTGTACGCGCGCGTCGATGCGCATCTGCAAGGTCGTACCTGGCTTGCCAGCGACAGCCACACCGGTGCCGATGCGTAT
TTGTTCGTCACCTTGCTGTGGGCGCAGAAAGCCGCTGTGAATCTGGATGGCTTGAACGCGCTGCAAGCGTTCGTGCAACG
CATGCTGGCCGATGCCGATGTGCAGGCTGCACTCAAGGCCGAGGGTCTGGCCTGGCAGCGCAGCCGTTTGCCACACGACG
CGTAA

Upstream 100 bases:

>100_bases
AATGGGCGACACCCTGCTCAAGCCTCCAATACCCGCTGCGCGCTCCACACGGCATCGTCTGCCCGCTAAGCTTGGGTCTT
CATTTCCGTGTGGATCGTCC

Downstream 100 bases:

>100_bases
TAACAAAAACGCCGGGCAATGCCCGGCGTTTTCATGACTGCCGTGATCGACCAACTCAGCCCAGCAGGTGCGCCACGCCG
CTGCGCTCTTCTTCCAGCTC

Product: glutathione S-transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGAVPLLLVDDWALTQNAAILNYIADIAPLTGLSG
DGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPALIARSQDDARVKLRTLYARVDAHLQGRTWLASDSHTGADAY
LFVTLLWAQKAAVNLDGLNALQAFVQRMLADADVQAALKAEGLAWQRSRLPHDA

Sequences:

>Translated_214_residues
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGAVPLLLVDDWALTQNAAILNYIADIAPLTGLSG
DGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPALIARSQDDARVKLRTLYARVDAHLQGRTWLASDSHTGADAY
LFVTLLWAQKAAVNLDGLNALQAFVQRMLADADVQAALKAEGLAWQRSRLPHDA
>Mature_214_residues
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGAVPLLLVDDWALTQNAAILNYIADIAPLTGLSG
DGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPALIARSQDDARVKLRTLYARVDAHLQGRTWLASDSHTGADAY
LFVTLLWAQKAAVNLDGLNALQAFVQRMLADADVQAALKAEGLAWQRSRLPHDA

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=207, Percent_Identity=38.6473429951691, Blast_Score=120, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 23335; Mature: 23335

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGAVPLLLVDDWALT
CCCCCCCCCCCHHCEEEEEECCCCEEEEEHHHHHCCCCCEEEECCCCCEEEEEECCCHHC
QNAAILNYIADIAPLTGLSGDGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPAL
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEECCCCCCCHHHCCCCCEECCCHH
IARSQDDARVKLRTLYARVDAHLQGRTWLASDSHTGADAYLFVTLLWAQKAAVNLDGLNA
EECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
LQAFVQRMLADADVQAALKAEGLAWQRSRLPHDA
HHHHHHHHHCCCCHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MKLYTKPGACSLADHIVLRWSGLPFDLSVVDAATMKSPEYLRLNPAGAVPLLLVDDWALT
CCCCCCCCCCCHHCEEEEEECCCCEEEEEHHHHHCCCCCEEEECCCCCEEEEEECCCHHC
QNAAILNYIADIAPLTGLSGDGTARSRAEINRWIAFVNADVHPTFKPIFGSTAYLQDPAL
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEECCCCCCCHHHCCCCCEECCCHH
IARSQDDARVKLRTLYARVDAHLQGRTWLASDSHTGADAYLFVTLLWAQKAAVNLDGLNA
EECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
LQAFVQRMLADADVQAALKAEGLAWQRSRLPHDA
HHHHHHHHHCCCCHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217; 8342943 [H]