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The map label for this gene is secY [H]

Identifier: 21241757

GI number: 21241757

Start: 1144633

End: 1145997

Strand: Direct

Name: secY [H]

Synonym: XAC0992

Alternate gene names: 21241757

Gene position: 1144633-1145997 (Clockwise)

Preceding gene: 21241756

Following gene: 21241758

Centisome position: 22.12

GC content: 60.66

Gene sequence:

>1365_bases
ATGGCGCAGGCTGGCATTGGTAACCTCGGCGGCGGGCTCGGCAAGTTCACGGAACTTCGCCAGCGGTTGCTGTTCGTCCT
CGGGGCATTGATCGTTTATCGCATCGGCTGCTATGTGCCGGTGCCTGGCGTGAATCCCGATGCCATGCTTTCGTTGATGC
AGGCGCAGGGCGGCGGCATCGTGGACATGTTCAACATGTTCTCGGGCGGCGCCCTGCACCGTTTCAGTATTTTTGCATTG
AACGTGATGCCGTATATCTCGGCATCGATCGTGATCCAGTTGGCCACGCACATCTTTCCCGCCCTCAAGGCGATGCAGAA
AGAAGGCGAATCGGGCCGACGCAAGATCACCCAATATTCGCGCATCGGTGCGGTGTTGCTGGCGGTGGTGCAGGGCGGCA
GTATCGCGCTGGCACTGCAGAACCAGACCGCCCCTGGTGGCGCTCCGGTGGTGTATGCGCCGGGCATGGGCTTCGTGCTC
ACCGCGGTGATCGCTTTGACCGCTGGTACCATCTTCCTGATGTGGGTAGGCGAGCAGGTTACCGAGCGCGGCATCGGTAA
CGGCGTATCGCTGATCATCTTTGCCGGCATCGTGGCTGGCCTGCCGTCGGCGGCCATCCAGACGGTCGAAGCCTTCCGCG
AAGGCAATCTGAGCTTCATTTCGCTGTTGTTGATCGTCATCACCATCCTGGCGTTCACGCTGTTCGTCGTGTTTGTCGAG
CGTGGGCAGCGGCGGATCACGGTCAACTACGCGCGCCGCCAGGGCGGTCGCAATGCGTACATGAACCAGACCTCGTTCTT
GCCGCTCAAGCTGAACATGGCCGGTGTGATTCCGCCGATCTTTGCGTCCAGCATCCTGGCATTCCCGGCAACGTTGTCGA
TGTGGTCGGGTCAGGCTGCATCGGGTGGTATCGGCTCGTGGCTGCAGAAGATTGCCAACGCGCTTGGCCCCGGTGAGCCG
GTACACATGCTGGTCTTCGCTGCGCTGATCATCGGTTTTGCATTCTTCTACACCGCGCTGGTGTTCAACTCGCAGGAAAC
CGCCGACAACCTCAAGAAATCGGGCGCGCTGATTCCGGGCATCCGTCCAGGCAAGGCCACCGCAGATTACGTCGATGGCG
TACTGACGCGCCTGACAGCTGCCGGTTCGTTGTACCTGGTAATCGTCTGCCTGCTGCCGGAAATCATGCGCACGCAGCTC
GGCACTTCGTTCCACTTCGGGGGCACCTCGCTATTGATTGCAGTGGTGGTGGTGATGGACTTCATTGCGCAGATCCAGGC
GCACCTGATGTCGCACCAGTATGAGAGCTTGCTGAAGAAGGCCAACCTCAAGGGCGGCTCACGCGGCGGTCTTGCGCGCG
GTTAA

Upstream 100 bases:

>100_bases
GAGCTGAGCAAGAAGTTCGTGCTGAAGGGCGTTGCGGCAACCGCAGGCGCCAAGGCGGCAATCGAAGCTGCCGGCGGCAG
CGTAGAGGAGTAATCGGCAG

Downstream 100 bases:

>100_bases
GTGGTACACTAGATCTTCATCACGTGAAGACGGCCTGGTTCCCGGGCCACGATCTTCCGATCAGAAGGGCGGCTCGCGCG
ACGTCTCGCGCGCGGGTGTG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAQAGIGNLGGGLGKFTELRQRLLFVLGALIVYRIGCYVPVPGVNPDAMLSLMQAQGGGIVDMFNMFSGGALHRFSIFAL
NVMPYISASIVIQLATHIFPALKAMQKEGESGRRKITQYSRIGAVLLAVVQGGSIALALQNQTAPGGAPVVYAPGMGFVL
TAVIALTAGTIFLMWVGEQVTERGIGNGVSLIIFAGIVAGLPSAAIQTVEAFREGNLSFISLLLIVITILAFTLFVVFVE
RGQRRITVNYARRQGGRNAYMNQTSFLPLKLNMAGVIPPIFASSILAFPATLSMWSGQAASGGIGSWLQKIANALGPGEP
VHMLVFAALIIGFAFFYTALVFNSQETADNLKKSGALIPGIRPGKATADYVDGVLTRLTAAGSLYLVIVCLLPEIMRTQL
GTSFHFGGTSLLIAVVVVMDFIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG

Sequences:

>Translated_454_residues
MAQAGIGNLGGGLGKFTELRQRLLFVLGALIVYRIGCYVPVPGVNPDAMLSLMQAQGGGIVDMFNMFSGGALHRFSIFAL
NVMPYISASIVIQLATHIFPALKAMQKEGESGRRKITQYSRIGAVLLAVVQGGSIALALQNQTAPGGAPVVYAPGMGFVL
TAVIALTAGTIFLMWVGEQVTERGIGNGVSLIIFAGIVAGLPSAAIQTVEAFREGNLSFISLLLIVITILAFTLFVVFVE
RGQRRITVNYARRQGGRNAYMNQTSFLPLKLNMAGVIPPIFASSILAFPATLSMWSGQAASGGIGSWLQKIANALGPGEP
VHMLVFAALIIGFAFFYTALVFNSQETADNLKKSGALIPGIRPGKATADYVDGVLTRLTAAGSLYLVIVCLLPEIMRTQL
GTSFHFGGTSLLIAVVVVMDFIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG
>Mature_453_residues
AQAGIGNLGGGLGKFTELRQRLLFVLGALIVYRIGCYVPVPGVNPDAMLSLMQAQGGGIVDMFNMFSGGALHRFSIFALN
VMPYISASIVIQLATHIFPALKAMQKEGESGRRKITQYSRIGAVLLAVVQGGSIALALQNQTAPGGAPVVYAPGMGFVLT
AVIALTAGTIFLMWVGEQVTERGIGNGVSLIIFAGIVAGLPSAAIQTVEAFREGNLSFISLLLIVITILAFTLFVVFVER
GQRRITVNYARRQGGRNAYMNQTSFLPLKLNMAGVIPPIFASSILAFPATLSMWSGQAASGGIGSWLQKIANALGPGEPV
HMLVFAALIIGFAFFYTALVFNSQETADNLKKSGALIPGIRPGKATADYVDGVLTRLTAAGSLYLVIVCLLPEIMRTQLG
TSFHFGGTSLLIAVVVVMDFIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=439, Percent_Identity=60.3644646924829, Blast_Score=481, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47995; Mature: 47864

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAGIGNLGGGLGKFTELRQRLLFVLGALIVYRIGCYVPVPGVNPDAMLSLMQAQGGGI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHCCCCH
VDMFNMFSGGALHRFSIFALNVMPYISASIVIQLATHIFPALKAMQKEGESGRRKITQYS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RIGAVLLAVVQGGSIALALQNQTAPGGAPVVYAPGMGFVLTAVIALTAGTIFLMWVGEQV
HHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEECCHHH
TERGIGNGVSLIIFAGIVAGLPSAAIQTVEAFREGNLSFISLLLIVITILAFTLFVVFVE
HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RGQRRITVNYARRQGGRNAYMNQTSFLPLKLNMAGVIPPIFASSILAFPATLSMWSGQAA
CCCCEEEEEHHHHCCCCCCCCCCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHCCCCCC
SGGIGSWLQKIANALGPGEPVHMLVFAALIIGFAFFYTALVFNSQETADNLKKSGALIPG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
IRPGKATADYVDGVLTRLTAAGSLYLVIVCLLPEIMRTQLGTSFHFGGTSLLIAVVVVMD
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
FIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AQAGIGNLGGGLGKFTELRQRLLFVLGALIVYRIGCYVPVPGVNPDAMLSLMQAQGGGI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHCCCCH
VDMFNMFSGGALHRFSIFALNVMPYISASIVIQLATHIFPALKAMQKEGESGRRKITQYS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RIGAVLLAVVQGGSIALALQNQTAPGGAPVVYAPGMGFVLTAVIALTAGTIFLMWVGEQV
HHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEECCHHH
TERGIGNGVSLIIFAGIVAGLPSAAIQTVEAFREGNLSFISLLLIVITILAFTLFVVFVE
HHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
RGQRRITVNYARRQGGRNAYMNQTSFLPLKLNMAGVIPPIFASSILAFPATLSMWSGQAA
CCCCEEEEEHHHHCCCCCCCCCCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHCCCCCC
SGGIGSWLQKIANALGPGEPVHMLVFAALIIGFAFFYTALVFNSQETADNLKKSGALIPG
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
IRPGKATADYVDGVLTRLTAAGSLYLVIVCLLPEIMRTQLGTSFHFGGTSLLIAVVVVMD
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
FIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]