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The map label for this gene is pntB [H]

Identifier: 21241694

GI number: 21241694

Start: 1085566

End: 1087023

Strand: Direct

Name: pntB [H]

Synonym: XAC0924

Alternate gene names: 21241694

Gene position: 1085566-1087023 (Clockwise)

Preceding gene: 21241693

Following gene: 21241696

Centisome position: 20.97

GC content: 64.95

Gene sequence:

>1458_bases
ATGAACGTCTCCACTGCCGAGTTGCTGTCGTGGGTGGTCAAGTCCAGTTACCTGGTTGCAGCCACCTTGTTCCTGCTCGG
TCTGCAGCGGATGGCGTCTCCATTGAGCGCGCGCAGCGGCATCCGTTGGGCCGGGCTGGGCATGTTGATCGCCACGGTGG
CCACGTTTTTCCTGCCCGAGTTGCACAACGTGCCGCTGATTCTGGCGGCGTTGGCGATCGGCACCGGCGTGGCGTGGTGG
TCGGCCAAGAAGGTCGCCATCACCGACATGCCGCAGATGGTGGCGCTGTACAACGGCATGGGCGGCGGCTCGGCGGCGGC
GATCGGCGCGGTGGAACTGCTGCGGTTTTCGTTCTTCGCCAATCGCGACACGGCGCATTGGAGCGCCCAGGCGGTTGCGG
AGCTGGCGGCGCGGCAGCCGGACACCGCCATGGTGGTGCTGGCGGTGATCGGTTCGGCGATCGGGGCGGTGTCGTTGTCG
GGGTCGATCATCGCGTGGGCCAAGCTCGATGGCCGGCTGGACCGGCGGATGACCTTCCCGGGGCAGCAAGCCTTCAATCT
GGCGGTGGCAGTGGCGGTGCTGGCCCTGGCCATCTGGGCGGCGGGCAGCCTGCAGCCGTTGGCGATCATCGCGTTCTTCG
TGGTGGCGTTGGCCCTGGGCGTGCTGATGACGCTACCGATCGGCGGTGCCGACATGCCGGTGGTGATTTCGCTCTACAAC
GCGTTTACCGGGTTGGCGGTGGCGTTCGAGGGGTATGTACTCGGCAACGAGGCACTGATCATCGCCGGCATGATGGTCGG
CGCGGCCGGCATTCTGCTGACGCGGTTGATGGCCAAGGCGATGAATCGTCCGATCAGCGGGGTGCTGTTTTCCAACTTCG
GCGGTGGCGGGCAGGCGCAGGAAATCAGCGGTGTGCAGAAGCCGATCGAGGCCGGCGATGTGGCGGCGATGATGGCCTTT
GCCGAGCGGGTGGTGATCGTGCCCGGCTATGGCATGGCAGTGGCGCAGGCACAGCACAAGATTTGGGAGCTGGCGCAGCG
CTTGATGGCGCGCGGTGTCAAGGTGAAGTTCGCGATCCATCCGGTCGCTGGGCGCATGCCGGGGCACATGAACGTGCTGC
TGGCCGAGGCCGGTGTGCCCTACGATCTGATCGCCGACATGGACGACATCAATCCGGAATTTGCCAGCACCGACGTGTCG
TTGGTGATCGGTGCCAACGACGTGGTCAATCCGGTCGCCAAGACCGATTCGGCCAGCCCGATCTACGGCATGCCGATTCT
GGACGTGGTCAATTCGCGCAACACGGTGGTGATCAAGCGCGGCAAGGGAACCGGCTTTGCCGGCATCGAGAATGCGCTGT
TCTACGCCGACAACACGCGCATGTTGTACGGCGATGGGGCAGAAGCCGCTGGTGCGCTGGTGAGTGAATTGAAAGCGCTG
GATGGCAGCGGGCATTGA

Upstream 100 bases:

>100_bases
TGGCGTTAGGTGCGGGAAACGCGGCGGGGGGCTACGTGGTCACCGAGCGAATGCTGGAGATGTTCAAGTCCAGCAAGAAG
TCGCCTGGCGGGGATAGGTC

Downstream 100 bases:

>100_bases
GTGTTGGTGTGTCGCCAGGCGCGCTCAGACGCTTGAGGCAACGCAGGGTCGGTCGTGTCCTGTTGCGTTACCGGAGGCGC
TTACACGCGCGGATCAAAGC

Product: pyridine nucleotide transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNVSTAELLSWVVKSSYLVAATLFLLGLQRMASPLSARSGIRWAGLGMLIATVATFFLPELHNVPLILAALAIGTGVAWW
SAKKVAITDMPQMVALYNGMGGGSAAAIGAVELLRFSFFANRDTAHWSAQAVAELAARQPDTAMVVLAVIGSAIGAVSLS
GSIIAWAKLDGRLDRRMTFPGQQAFNLAVAVAVLALAIWAAGSLQPLAIIAFFVVALALGVLMTLPIGGADMPVVISLYN
AFTGLAVAFEGYVLGNEALIIAGMMVGAAGILLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGVQKPIEAGDVAAMMAF
AERVVIVPGYGMAVAQAQHKIWELAQRLMARGVKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVS
LVIGANDVVNPVAKTDSASPIYGMPILDVVNSRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKAL
DGSGH

Sequences:

>Translated_485_residues
MNVSTAELLSWVVKSSYLVAATLFLLGLQRMASPLSARSGIRWAGLGMLIATVATFFLPELHNVPLILAALAIGTGVAWW
SAKKVAITDMPQMVALYNGMGGGSAAAIGAVELLRFSFFANRDTAHWSAQAVAELAARQPDTAMVVLAVIGSAIGAVSLS
GSIIAWAKLDGRLDRRMTFPGQQAFNLAVAVAVLALAIWAAGSLQPLAIIAFFVVALALGVLMTLPIGGADMPVVISLYN
AFTGLAVAFEGYVLGNEALIIAGMMVGAAGILLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGVQKPIEAGDVAAMMAF
AERVVIVPGYGMAVAQAQHKIWELAQRLMARGVKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVS
LVIGANDVVNPVAKTDSASPIYGMPILDVVNSRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKAL
DGSGH
>Mature_485_residues
MNVSTAELLSWVVKSSYLVAATLFLLGLQRMASPLSARSGIRWAGLGMLIATVATFFLPELHNVPLILAALAIGTGVAWW
SAKKVAITDMPQMVALYNGMGGGSAAAIGAVELLRFSFFANRDTAHWSAQAVAELAARQPDTAMVVLAVIGSAIGAVSLS
GSIIAWAKLDGRLDRRMTFPGQQAFNLAVAVAVLALAIWAAGSLQPLAIIAFFVVALALGVLMTLPIGGADMPVVISLYN
AFTGLAVAFEGYVLGNEALIIAGMMVGAAGILLTRLMAKAMNRPISGVLFSNFGGGGQAQEISGVQKPIEAGDVAAMMAF
AERVVIVPGYGMAVAQAQHKIWELAQRLMARGVKVKFAIHPVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVS
LVIGANDVVNPVAKTDSASPIYGMPILDVVNSRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKAL
DGSGH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=425, Percent_Identity=37.8823529411765, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI122939153, Length=425, Percent_Identity=37.8823529411765, Blast_Score=288, Evalue=6e-78,
Organism=Escherichia coli, GI1787886, Length=477, Percent_Identity=41.0901467505241, Blast_Score=345, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17550456, Length=477, Percent_Identity=36.0587002096436, Blast_Score=291, Evalue=7e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50452; Mature: 50452

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSTAELLSWVVKSSYLVAATLFLLGLQRMASPLSARSGIRWAGLGMLIATVATFFLPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
LHNVPLILAALAIGTGVAWWSAKKVAITDMPQMVALYNGMGGGSAAAIGAVELLRFSFFA
HCCCHHHHHHHHHHCCHHECCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
NRDTAHWSAQAVAELAARQPDTAMVVLAVIGSAIGAVSLSGSIIAWAKLDGRLDRRMTFP
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHCCCCCC
GQQAFNLAVAVAVLALAIWAAGSLQPLAIIAFFVVALALGVLMTLPIGGADMPVVISLYN
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AFTGLAVAFEGYVLGNEALIIAGMMVGAAGILLTRLMAKAMNRPISGVLFSNFGGGGQAQ
HHHHHHHHEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
EISGVQKPIEAGDVAAMMAFAERVVIVPGYGMAVAQAQHKIWELAQRLMARGVKVKFAIH
HHHHHHCCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
PVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVSLVIGANDVVNPVAKTDSASP
CCCCCCCCCCEEEEECCCCCHHHHCCCHHCCCCCCCCCEEEEECCCHHHCHHHCCCCCCC
IYGMPILDVVNSRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKAL
CCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHH
DGSGH
CCCCC
>Mature Secondary Structure
MNVSTAELLSWVVKSSYLVAATLFLLGLQRMASPLSARSGIRWAGLGMLIATVATFFLPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHH
LHNVPLILAALAIGTGVAWWSAKKVAITDMPQMVALYNGMGGGSAAAIGAVELLRFSFFA
HCCCHHHHHHHHHHCCHHECCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
NRDTAHWSAQAVAELAARQPDTAMVVLAVIGSAIGAVSLSGSIIAWAKLDGRLDRRMTFP
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHCCCCCC
GQQAFNLAVAVAVLALAIWAAGSLQPLAIIAFFVVALALGVLMTLPIGGADMPVVISLYN
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AFTGLAVAFEGYVLGNEALIIAGMMVGAAGILLTRLMAKAMNRPISGVLFSNFGGGGQAQ
HHHHHHHHEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
EISGVQKPIEAGDVAAMMAFAERVVIVPGYGMAVAQAQHKIWELAQRLMARGVKVKFAIH
HHHHHHCCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
PVAGRMPGHMNVLLAEAGVPYDLIADMDDINPEFASTDVSLVIGANDVVNPVAKTDSASP
CCCCCCCCCCEEEEECCCCCHHHHCCCHHCCCCCCCCCEEEEECCCHHHCHHHCCCCCCC
IYGMPILDVVNSRNTVVIKRGKGTGFAGIENALFYADNTRMLYGDGAEAAGALVSELKAL
CCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHHH
DGSGH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]