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The map label for this gene is ahpC [H]

Identifier: 21241677

GI number: 21241677

Start: 1068709

End: 1069272

Strand: Reverse

Name: ahpC [H]

Synonym: XAC0907

Alternate gene names: 21241677

Gene position: 1069272-1068709 (Counterclockwise)

Preceding gene: 21241680

Following gene: 21241676

Centisome position: 20.66

GC content: 60.82

Gene sequence:

>564_bases
ATGTCTCTCATCAACACCCAGGTCCAGCCGTTCAAGGCGAATGCGTACCACAATGGCAACTTCATCGAAGTCACCGAGGC
CAGCCTGAAGGGCAAGTGGTCGGTGCTGATCTTCATGCCGGCCGCATTCACCTTCAACTGCCCGACCGAAGTGGAAGACG
CCGCCGACAACTATGCCGCCTTCCAGAAGGCTGGCGCCGAGGTCTATATCGTCACCACCGACACGCATTTCTCGCACAAG
GTGTGGCACGAAACCTCGCCGGCCGTGGGCAAGGCGCAGTTCCCGTTGATCGGCGACCCGACCCACAAGCTGACCCGCGC
GTTCGGCGTGCATATTGAAGAAGAAGGCCTGGCCCTGCGTGGCACCTTCATCATCAATCCGGAAGGCGTGATCAAGACGC
TGGAAATCCACGACAACTCCATCGCCCGCGACGTCACCGAGACGCTGCGCAAGCTGACCGCTGCACAGTTCGTGGCCAAC
AATCCTGGCCAGGTCTGCCCGGCCAAGTGGAAGGAAGGCGCCAAGACCCTGGCTCCGTCGCTGGACCTGGTCGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
ATCTATGTAATTCCATCAATCGATTTGAGGAATCTATCGATCCTGCCTACCATGGCGCCTGTTCCATCCCCCGCCCCCTT
TTACCGCACGAGGAAACTCA

Downstream 100 bases:

>100_bases
GCCGGCTGTCATCTCCGGCCCAGTCGGGCCGGGGGTGAACCGGAGCCGGTGCCGGGCTGCCCGCCAGCCGCCGCCAGCAC
GCACCCCGACCTCGCGCCGG

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLINTQVQPFKANAYHNGNFIEVTEASLKGKWSVLIFMPAAFTFNCPTEVEDAADNYAAFQKAGAEVYIVTTDTHFSHK
VWHETSPAVGKAQFPLIGDPTHKLTRAFGVHIEEEGLALRGTFIINPEGVIKTLEIHDNSIARDVTETLRKLTAAQFVAN
NPGQVCPAKWKEGAKTLAPSLDLVGKI

Sequences:

>Translated_187_residues
MSLINTQVQPFKANAYHNGNFIEVTEASLKGKWSVLIFMPAAFTFNCPTEVEDAADNYAAFQKAGAEVYIVTTDTHFSHK
VWHETSPAVGKAQFPLIGDPTHKLTRAFGVHIEEEGLALRGTFIINPEGVIKTLEIHDNSIARDVTETLRKLTAAQFVAN
NPGQVCPAKWKEGAKTLAPSLDLVGKI
>Mature_186_residues
SLINTQVQPFKANAYHNGNFIEVTEASLKGKWSVLIFMPAAFTFNCPTEVEDAADNYAAFQKAGAEVYIVTTDTHFSHKV
WHETSPAVGKAQFPLIGDPTHKLTRAFGVHIEEEGLALRGTFIINPEGVIKTLEIHDNSIARDVTETLRKLTAAQFVANN
PGQVCPAKWKEGAKTLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=41.8994413407821, Blast_Score=142, Evalue=1e-34,
Organism=Homo sapiens, GI5802974, Length=179, Percent_Identity=43.0167597765363, Blast_Score=141, Evalue=3e-34,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=40, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=36.5714285714286, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=36.5714285714286, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=36.5714285714286, Blast_Score=129, Evalue=1e-30,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=35.5555555555556, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=44.1558441558442, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=57.2192513368984, Blast_Score=241, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=39.5480225988701, Blast_Score=138, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=38.5057471264368, Blast_Score=133, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=38.5057471264368, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=39.7790055248619, Blast_Score=142, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=40.6593406593407, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=25.7668711656442, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=38.4615384615385, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=37.3626373626374, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=37.3626373626374, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=37.8531073446328, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=38.2352941176471, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=38.2352941176471, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=28.4810126582279, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=28.8461538461538, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20462; Mature: 20331

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTQVQPFKANAYHNGNFIEVTEASLKGKWSVLIFMPAAFTFNCPTEVEDAADNYAA
CCCCCCCCCCEECCCEECCCEEEEEECCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHH
FQKAGAEVYIVTTDTHFSHKVWHETSPAVGKAQFPLIGDPTHKLTRAFGVHIEEEGLALR
HHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCEEEE
GTFIINPEGVIKTLEIHDNSIARDVTETLRKLTAAQFVANNPGQVCPAKWKEGAKTLAPS
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHCCC
LDLVGKI
CHHHCCC
>Mature Secondary Structure 
SLINTQVQPFKANAYHNGNFIEVTEASLKGKWSVLIFMPAAFTFNCPTEVEDAADNYAA
CCCCCCCCCEECCCEECCCEEEEEECCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHH
FQKAGAEVYIVTTDTHFSHKVWHETSPAVGKAQFPLIGDPTHKLTRAFGVHIEEEGLALR
HHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCEEEE
GTFIINPEGVIKTLEIHDNSIARDVTETLRKLTAAQFVANNPGQVCPAKWKEGAKTLAPS
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHCCC
LDLVGKI
CHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]