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The map label for this gene is lgt

Identifier: 21241611

GI number: 21241611

Start: 1001632

End: 1002522

Strand: Direct

Name: lgt

Synonym: XAC0841

Alternate gene names: 21241611

Gene position: 1001632-1002522 (Clockwise)

Preceding gene: 21241610

Following gene: 21241612

Centisome position: 19.35

GC content: 63.3

Gene sequence:

>891_bases
ATGATCTATCTGCACGCCATCGACCCCATCGCTTTCTCGCTCGGCCCGGTGCAGGTGCACTGGTACGGCTTGATGTACTT
GGCGGCGTTTTTCTCGGCCTGGGCCCTGGGCCGTTCGCGCATCCTGCGCGGTCGCTTGCCCGGGGTAGACATGGATGGTT
TTTCCGACCTGCTGTTCTACGGCATGCTCGGCGTGGTGTTGGGTGGGCGCATCGGCTACATGCTGTTCTATGCGTTCGAG
ACCTTCCTGGCCAATCCGCTGATCCTGTTCAAGGTCTGGGAAGGCGGCATGAGCTTCCACGGCGGCCTGCTTGGCGTGTT
GATCGCTTGTTGGTTGTGGGCGCGCAAGCACCGGTTGCACTTCTTCGATGTGATGGACTTTGTCGCCCCGCTGGTGCCGC
TGGGTCTTGGTTTCGGGAGGCTCGGCAATTTCGTCGGCGGCGAATTGTGGGGAAAATTCACCCAGGCCGGCTGGGGCGTG
ATCTTTCCGCATGCGCCGGAACTGGCCGACCGGTTGCCCGCGCAGATCCAGGCGCAGTACGCCGCCGGCGCGTTGAACCA
GTTCGCACGCCACCCCTCGCAGCTCTATGAAGCTGCGCTGGAAGGGGTCGTGATGTTCGTGGTGTTGTGGACGTTCTCGA
TGAAGCCGCGCGCACGGTATGCGGTCTCCGGCCTGTTCGCATTGCTGTATGGCGTGTTCCGTTTCATCGTCGAATTCGTG
CGCGTACCCGACGCACCGATCGGCTACCTGGCCTTCAATTGGCTGACGATGGGCCAGATTCTGAGCCTGCCGTTGGTTGC
GGTTGGCCTGGTGCTGCTGGCGATGTCGCGCCGCGCGCCGGTGTTGCAGCCGGTGCTGCCGGTGCCCGCGGGCGTGGAGG
CTGCCAAGTGA

Upstream 100 bases:

>100_bases
CGCAGCATGAAGACGAGCTACCTGACCGGCCGCGGATTTTAGGCTGAGCGCGTGCGAGGTGTCAGAATAGCGGCCTCGCT
CTACGTGATACGCGGTCCGC

Downstream 100 bases:

>100_bases
AGCCGTACCTGGAGTTGTTGCAGCACGTGCTGGACCACGGCGCAGAGAAGTCCGACCGCACCGGTACCGGCACGCGCAGC
GTGTTCGGCTGGCAGATGCG

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MIYLHAIDPIAFSLGPVQVHWYGLMYLAAFFSAWALGRSRILRGRLPGVDMDGFSDLLFYGMLGVVLGGRIGYMLFYAFE
TFLANPLILFKVWEGGMSFHGGLLGVLIACWLWARKHRLHFFDVMDFVAPLVPLGLGFGRLGNFVGGELWGKFTQAGWGV
IFPHAPELADRLPAQIQAQYAAGALNQFARHPSQLYEAALEGVVMFVVLWTFSMKPRARYAVSGLFALLYGVFRFIVEFV
RVPDAPIGYLAFNWLTMGQILSLPLVAVGLVLLAMSRRAPVLQPVLPVPAGVEAAK

Sequences:

>Translated_296_residues
MIYLHAIDPIAFSLGPVQVHWYGLMYLAAFFSAWALGRSRILRGRLPGVDMDGFSDLLFYGMLGVVLGGRIGYMLFYAFE
TFLANPLILFKVWEGGMSFHGGLLGVLIACWLWARKHRLHFFDVMDFVAPLVPLGLGFGRLGNFVGGELWGKFTQAGWGV
IFPHAPELADRLPAQIQAQYAAGALNQFARHPSQLYEAALEGVVMFVVLWTFSMKPRARYAVSGLFALLYGVFRFIVEFV
RVPDAPIGYLAFNWLTMGQILSLPLVAVGLVLLAMSRRAPVLQPVLPVPAGVEAAK
>Mature_296_residues
MIYLHAIDPIAFSLGPVQVHWYGLMYLAAFFSAWALGRSRILRGRLPGVDMDGFSDLLFYGMLGVVLGGRIGYMLFYAFE
TFLANPLILFKVWEGGMSFHGGLLGVLIACWLWARKHRLHFFDVMDFVAPLVPLGLGFGRLGNFVGGELWGKFTQAGWGV
IFPHAPELADRLPAQIQAQYAAGALNQFARHPSQLYEAALEGVVMFVVLWTFSMKPRARYAVSGLFALLYGVFRFIVEFV
RVPDAPIGYLAFNWLTMGQILSLPLVAVGLVLLAMSRRAPVLQPVLPVPAGVEAAK

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=287, Percent_Identity=48.4320557491289, Blast_Score=245, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_XANAC (Q8PP47)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641193.1
- GeneID:   1154912
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0841
- NMPDR:   fig|190486.1.peg.837
- HOGENOM:   HBG450278
- OMA:   NPIAFSL
- ProtClustDB:   PRK00052
- BioCyc:   XAXO190486:XAC0841-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640
- TIGRFAMs:   TIGR00544

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 32742; Mature: 32742

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdca7a3c)-; HASH(0xddbaddc)-; HASH(0xdb0eaf0)-; HASH(0xdc17810)-; HASH(0xddc11cc)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYLHAIDPIAFSLGPVQVHWYGLMYLAAFFSAWALGRSRILRGRLPGVDMDGFSDLLFY
CEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
GMLGVVLGGRIGYMLFYAFETFLANPLILFKVWEGGMSFHGGLLGVLIACWLWARKHRLH
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
FFDVMDFVAPLVPLGLGFGRLGNFVGGELWGKFTQAGWGVIFPHAPELADRLPAQIQAQY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCHHHHHHH
AAGALNQFARHPSQLYEAALEGVVMFVVLWTFSMKPRARYAVSGLFALLYGVFRFIVEFV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVPDAPIGYLAFNWLTMGQILSLPLVAVGLVLLAMSRRAPVLQPVLPVPAGVEAAK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MIYLHAIDPIAFSLGPVQVHWYGLMYLAAFFSAWALGRSRILRGRLPGVDMDGFSDLLFY
CEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
GMLGVVLGGRIGYMLFYAFETFLANPLILFKVWEGGMSFHGGLLGVLIACWLWARKHRLH
HHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
FFDVMDFVAPLVPLGLGFGRLGNFVGGELWGKFTQAGWGVIFPHAPELADRLPAQIQAQY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHCCHHHHHHH
AAGALNQFARHPSQLYEAALEGVVMFVVLWTFSMKPRARYAVSGLFALLYGVFRFIVEFV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RVPDAPIGYLAFNWLTMGQILSLPLVAVGLVLLAMSRRAPVLQPVLPVPAGVEAAK
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12024217