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The map label for this gene is nrdR

Identifier: 21241515

GI number: 21241515

Start: 885048

End: 885572

Strand: Direct

Name: nrdR

Synonym: XAC0744

Alternate gene names: 21241515

Gene position: 885048-885572 (Clockwise)

Preceding gene: 21241514

Following gene: 21241516

Centisome position: 17.1

GC content: 64.19

Gene sequence:

>525_bases
ATGCATTGCCCCTTCTGCCAGCACAACGACACCCGCGTGATCGATTCGCGGGTGTCCGAAGACGGCACGACGATCCGTCG
GCGCCGCGAGTGCGAGGCGTGCGGCGAACGGTTCAGTACGTTGGAAACGATCGAGCTGAAGCTGCCCACCGTGGTCAAGA
GCGATGGTGGGCGCGAGGCGTTCGATGCACGCAAGCTGCGCACCAGCTTCGACCGCGCGCTGCAAAAGCGGCCGGTGGCC
GAAGAGCAGATCGAAGCGGCGGTGCGCGCGGTGGTGCACCAGCTGCGCATGTCCGGCGAGCGCGAAGTGGGTTCGCTGCG
GGTAGGCGAATACGTGATGGTGGAGCTGCGCAAGCTCGATCATGTCGGCTATGTGCGCTTTGCCTCGGTGTATCGCAGTT
TTCAGGACGTGGCCGACTTCCGCGAGGAAATCGAAAAGCTCGAACGCGAACTGCCGGTCGGCAGCGAACAACTGCCGCTG
CTGGAAGCGGCATTGGAACGCGCCGGCAAACCCGGCAAGCGATGA

Upstream 100 bases:

>100_bases
ACGGAATGGGGAATGGGGAGACGAGAATGGTAAAAGCGACGCTGCGATAGCTCTGCTGGCCCGATTCCTTAATTCCCCTC
TCCCTATTCCCGGACGTCTG

Downstream 100 bases:

>100_bases
GCGCGATGCGCATCGCCTGCGTTGCGCGAACGCCGCAGTACCTGCCTGCGATTGCGCAAGCGCATCTACAGGCCTTCGGC
GCGCTGTTGCCGGAGTGGAA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVA
EEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPL
LEAALERAGKPGKR

Sequences:

>Translated_174_residues
MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVA
EEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPL
LEAALERAGKPGKR
>Mature_174_residues
MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVA
EEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPL
LEAALERAGKPGKR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=54.7297297297297, Blast_Score=170, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_XANAC (Q8PPE2)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641097.1
- GeneID:   1154815
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0744
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   XAXO190486:XAC0744-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 19931; Mature: 19931

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHEECCCCCHH
FDARKLRTSFDRALQKRPVAEEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEAALERAGKPGKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREA
CCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHEECCCCCHH
FDARKLRTSFDRALQKRPVAEEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
HVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEAALERAGKPGKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217