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The map label for this gene is xcsE [H]

Identifier: 21241467

GI number: 21241467

Start: 826720

End: 828207

Strand: Direct

Name: xcsE [H]

Synonym: XAC0696

Alternate gene names: 21241467

Gene position: 826720-828207 (Clockwise)

Preceding gene: 21241466

Following gene: 21241468

Centisome position: 15.97

GC content: 66.67

Gene sequence:

>1488_bases
ATGAGCACTGCGCGCGCCGGCATTTCCTATGCATTCGCCAAGCGTCACGGCGTGGTGCTGCTTGGCAGCGACACCACAGC
GCAGATCGGGTTGCGCGAAGGTGGCGATGTGCAGGCCTTGATCGAGTTGCGCCGCGCGTTGGGCCTGCCATTGCAGGTGC
GCACGCTGGCGCCGTCGGTGTTCGACCGGCATGTGTCGGAGATCTACGCCGATGCCGGGCTGGAACAAGGCGTGCAGGTG
GAAGCGCTGGATCTGCATGGCAGCCTGGATTCGTTGATCGACGACATCCCCACCGCCGATCTGCTCGACAGCCAGGACGA
TGCGCCGATCATCCGCCTGATCAACGGCATCATCGCCGAAGCCGCGCGGCTGGGTGCATCCGACGTGCATCTGGAATCCT
ACGAATCGCGTTTGCGCGTGCGCCTGCGCGTGGATGGCGTGATGCGCGAGGCAGCCACGCTGCCCGGACGCATCGCACCG
CTGCTTGTGTCGCGCGTTAAGGTGATGGCGCGGCTGGATATCGCCGAAAAACGCATCCCGCAGGATGGGCGCGTGTCGCT
GGTGATGGGGGCCAAGGCGCTGGATGTGCGCGTCTCCACCTTGCCCACGCGCGGCAGCGAGCGCGTGGTGCTGCGTATTC
TGGATAAGGAACAGGGCACGCTGTCGCTGGCGCAACTGGGCATGCCACCGGCGGTGATGCACACCGTGCAGCGTGCCTTG
CAGGTGCCCAACGGCATCGTGCTGGTCACCGGGCCCACCGGTTCGGGCAAGACCACGACCTTGTACGCGGCGCTGCGCTT
GCTCAACGATGGCTCGCGCAACATCCTCACCGTGGAAGACCCGGTGGAGTACGCCATCGACGGCGTCGGCCAGACCCAGG
TCAACGCACGTGTCGGCATGACCTTCGCCGCCGGCCTGCGCGCGATCCTGCGCCAGGACCCGGACGTGGTGATGATCGGC
GAGATCCGCGATACCGAGACCGCGCAGATTGCGGTGCAGGCCAGCCTCACCGGCCATCTGGTGCTCTCCACCGTGCACAC
CAATGATGCAGTGGGTGCGGTCACGCGGTTGCGCGATATGGGGATCGAGCCGTTTCTGCTGGCATCGAGCCTGCGACTGA
TTCTGGCGCAGCGGCTGGTGCGGCGCTTGTGCACGCAGTGCCGCAGTGCACGGCCGATGGACGCTGGGACGGCCCACCTG
TTGCGGGCGCCGGCCGATGCAGTGATCTACGCAGCGGCCGGCTGCAACGCCTGCCACCACAGCGGATACGCCGGGCGCGT
GGGTATCTACGAAGCGATTGCGGTAGACGATGCGATGCGCCGTTTGATCGGCGACAACGCCGACGAAGACGCACTGGCTG
CGGTCGCCTTCGCACGCGTACCGCGGCTGGGCGAAGCGGCACGGGCGGCCGTGCTGCAAGGCCTGACCACGCTGGAAGAA
GCGCTGCGTGTGACCCGCCAACAGGACGATGCGCATGCCGCAGTTTGA

Upstream 100 bases:

>100_bases
CGTGCTCAGCCGCCGCAGTTGCCGGCACGTCCCTCGTCAGTTGCGCCGGCACCGGCAACGACACCTGCGCCCGGCGCACG
TCCCGTGCAGCGGTGACGCC

Downstream 100 bases:

>100_bases
TTACACCGTGCTCGATCTGCATGGGCGCAACCGGCACGGCGTGATCAGCGCCGACAGCATAAACAGCGCACGTGCGCAGC
TGGAACAGCGCCAATGGGTG

Product: type II secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSTARAGISYAFAKRHGVVLLGSDTTAQIGLREGGDVQALIELRRALGLPLQVRTLAPSVFDRHVSEIYADAGLEQGVQV
EALDLHGSLDSLIDDIPTADLLDSQDDAPIIRLINGIIAEAARLGASDVHLESYESRLRVRLRVDGVMREAATLPGRIAP
LLVSRVKVMARLDIAEKRIPQDGRVSLVMGAKALDVRVSTLPTRGSERVVLRILDKEQGTLSLAQLGMPPAVMHTVQRAL
QVPNGIVLVTGPTGSGKTTTLYAALRLLNDGSRNILTVEDPVEYAIDGVGQTQVNARVGMTFAAGLRAILRQDPDVVMIG
EIRDTETAQIAVQASLTGHLVLSTVHTNDAVGAVTRLRDMGIEPFLLASSLRLILAQRLVRRLCTQCRSARPMDAGTAHL
LRAPADAVIYAAAGCNACHHSGYAGRVGIYEAIAVDDAMRRLIGDNADEDALAAVAFARVPRLGEAARAAVLQGLTTLEE
ALRVTRQQDDAHAAV

Sequences:

>Translated_495_residues
MSTARAGISYAFAKRHGVVLLGSDTTAQIGLREGGDVQALIELRRALGLPLQVRTLAPSVFDRHVSEIYADAGLEQGVQV
EALDLHGSLDSLIDDIPTADLLDSQDDAPIIRLINGIIAEAARLGASDVHLESYESRLRVRLRVDGVMREAATLPGRIAP
LLVSRVKVMARLDIAEKRIPQDGRVSLVMGAKALDVRVSTLPTRGSERVVLRILDKEQGTLSLAQLGMPPAVMHTVQRAL
QVPNGIVLVTGPTGSGKTTTLYAALRLLNDGSRNILTVEDPVEYAIDGVGQTQVNARVGMTFAAGLRAILRQDPDVVMIG
EIRDTETAQIAVQASLTGHLVLSTVHTNDAVGAVTRLRDMGIEPFLLASSLRLILAQRLVRRLCTQCRSARPMDAGTAHL
LRAPADAVIYAAAGCNACHHSGYAGRVGIYEAIAVDDAMRRLIGDNADEDALAAVAFARVPRLGEAARAAVLQGLTTLEE
ALRVTRQQDDAHAAV
>Mature_494_residues
STARAGISYAFAKRHGVVLLGSDTTAQIGLREGGDVQALIELRRALGLPLQVRTLAPSVFDRHVSEIYADAGLEQGVQVE
ALDLHGSLDSLIDDIPTADLLDSQDDAPIIRLINGIIAEAARLGASDVHLESYESRLRVRLRVDGVMREAATLPGRIAPL
LVSRVKVMARLDIAEKRIPQDGRVSLVMGAKALDVRVSTLPTRGSERVVLRILDKEQGTLSLAQLGMPPAVMHTVQRALQ
VPNGIVLVTGPTGSGKTTTLYAALRLLNDGSRNILTVEDPVEYAIDGVGQTQVNARVGMTFAAGLRAILRQDPDVVMIGE
IRDTETAQIAVQASLTGHLVLSTVHTNDAVGAVTRLRDMGIEPFLLASSLRLILAQRLVRRLCTQCRSARPMDAGTAHLL
RAPADAVIYAAAGCNACHHSGYAGRVGIYEAIAVDDAMRRLIGDNADEDALAAVAFARVPRLGEAARAAVLQGLTTLEEA
LRVTRQQDDAHAAV

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=482, Percent_Identity=50.8298755186722, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1786296, Length=384, Percent_Identity=44.7916666666667, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI87082188, Length=279, Percent_Identity=37.6344086021505, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 52807; Mature: 52675

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTARAGISYAFAKRHGVVLLGSDTTAQIGLREGGDVQALIELRRALGLPLQVRTLAPSV
CCCCHHCHHHHHHHHCCEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEHHHCHHH
FDRHVSEIYADAGLEQGVQVEALDLHGSLDSLIDDIPTADLLDSQDDAPIIRLINGIIAE
HHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHH
AARLGASDVHLESYESRLRVRLRVDGVMREAATLPGRIAPLLVSRVKVMARLDIAEKRIP
HHHCCCCCCHHHHHHHHEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QDGRVSLVMGAKALDVRVSTLPTRGSERVVLRILDKEQGTLSLAQLGMPPAVMHTVQRAL
CCCCEEEEECCEEEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHH
QVPNGIVLVTGPTGSGKTTTLYAALRLLNDGSRNILTVEDPVEYAIDGVGQTQVNARVGM
HCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCCEECHHHCH
TFAAGLRAILRQDPDVVMIGEIRDTETAQIAVQASLTGHLVLSTVHTNDAVGAVTRLRDM
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCEEEEEEEECCCHHHHHHHHHHC
GIEPFLLASSLRLILAQRLVRRLCTQCRSARPMDAGTAHLLRAPADAVIYAAAGCNACHH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEECCCCHHHC
SGYAGRVGIYEAIAVDDAMRRLIGDNADEDALAAVAFARVPRLGEAARAAVLQGLTTLEE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ALRVTRQQDDAHAAV
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
STARAGISYAFAKRHGVVLLGSDTTAQIGLREGGDVQALIELRRALGLPLQVRTLAPSV
CCCHHCHHHHHHHHCCEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEHHHCHHH
FDRHVSEIYADAGLEQGVQVEALDLHGSLDSLIDDIPTADLLDSQDDAPIIRLINGIIAE
HHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHH
AARLGASDVHLESYESRLRVRLRVDGVMREAATLPGRIAPLLVSRVKVMARLDIAEKRIP
HHHCCCCCCHHHHHHHHEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
QDGRVSLVMGAKALDVRVSTLPTRGSERVVLRILDKEQGTLSLAQLGMPPAVMHTVQRAL
CCCCEEEEECCEEEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHH
QVPNGIVLVTGPTGSGKTTTLYAALRLLNDGSRNILTVEDPVEYAIDGVGQTQVNARVGM
HCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHCCCCCCEECHHHCH
TFAAGLRAILRQDPDVVMIGEIRDTETAQIAVQASLTGHLVLSTVHTNDAVGAVTRLRDM
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCCEEEEEEEECCCHHHHHHHHHHC
GIEPFLLASSLRLILAQRLVRRLCTQCRSARPMDAGTAHLLRAPADAVIYAAAGCNACHH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEECCCCHHHC
SGYAGRVGIYEAIAVDDAMRRLIGDNADEDALAAVAFARVPRLGEAARAAVLQGLTTLEE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ALRVTRQQDDAHAAV
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]