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The map label for this gene is mreB [H]

Identifier: 21241427

GI number: 21241427

Start: 776860

End: 777906

Strand: Direct

Name: mreB [H]

Synonym: XAC0656

Alternate gene names: 21241427

Gene position: 776860-777906 (Clockwise)

Preceding gene: 21241424

Following gene: 21241428

Centisome position: 15.01

GC content: 65.81

Gene sequence:

>1047_bases
ATGTTCAAGAAACTCCGCGGCATGTTCTCCAACGACCTGTCCATCGATTTGGGCACGGCCAATACGCTGATCTACGTGCG
CGGACAGGGCATCGTGCTGAACGAGCCGTCGGTGGTTGCGGTGCGTCAGGATCGCGCGATCGGCGGCACGCGCTCGGTCG
CCGCCGTCGGTGCGGAGGCCAAGCAGATGCTCGGCCGTACCCCCGGCCACATCACCACGATTCGCCCGATGAAGGACGGC
GTCATCGCCGACTTCACCTACACCGAAGCGATGCTGAAGCACTTCATCAAGAAGGTGCACAAATCGCGCTTCCTGCGCCC
CAGCCCACGCGTGCTGGTGTGCGTGCCGGCTGGCTCCACGCAGGTCGAGCGCCGCGCCATCAAGGAATCCGCGGAAGAGG
CCGGTGCGCGCGACGTCTATCTGATCGAAGAGCCGATGGCCGCGGCGATCGGTGCCGGCATGCCGGTGACCGAGGCGCGC
GGTTCGATGGTCATCGACATCGGCGGCGGCACCACCGAGGTGGCGGTGATCTCGCTCAACGGCATCGTGTATTCGCAGTC
GGTACGTGTGGGTGGCGACCGGTTCGACGAGTCGATCACCAATTACGTGCGCCGTAACCACGGCATGCTGATCGGTGAGG
CCACGGCCGAGCGCATCAAGCTGCAGATCGGCTGCGCCTACCCGCAGGACGAGGTGCAGGAGATGGAAATCTCCGGCCGC
AACCTCGCCGAGGGCGTGCCGAAGATGATCAAGATCAATTCCAACGAAGTGCTCGAAGCGCTGCACGAGCCGTTGTCGGG
CATCGTCTCGGCAGTGAAGCTGGCGCTGGAGCAGACACCGCCGGAACTGTGCGCCGACGTCGCCGAGCGCGGCATCGTGC
TCACCGGTGGCGGCGCGCTGCTACGCGATCTGGACCGGCTCATCTCCGAAGAAACCGGCCTGCACGTGCAGGTGGCCGAC
GACCCGCTCACCTGCGTGGCCCGCGGTGGCGGCCGGGCGCTGGAGCTGGTGGACATGCATGGCAACGAGTTCTTCGCGCC
GGAGTGA

Upstream 100 bases:

>100_bases
CACCCCGGGGGGGATTGCTAGGCTAGCCGACTTCGTTTTCTGCCCAAAATTTCGCCAGTCTGGCGGCGGGCACGCGACTT
ACCCAGGAACGACTCCCTCG

Downstream 100 bases:

>100_bases
AGCGCTCGGGAATCGGGAATCGGGAAAGGGGAATCGTGAGAGCGGTTCCTGCCTACGGCCCTGAGTGGTTGCATCGTGAT
CCCGCCAATGTGAGTTCTCG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MFKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGAEAKQMLGRTPGHITTIRPMKDG
VIADFTYTEAMLKHFIKKVHKSRFLRPSPRVLVCVPAGSTQVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEAR
GSMVIDIGGGTTEVAVISLNGIVYSQSVRVGGDRFDESITNYVRRNHGMLIGEATAERIKLQIGCAYPQDEVQEMEISGR
NLAEGVPKMIKINSNEVLEALHEPLSGIVSAVKLALEQTPPELCADVAERGIVLTGGGALLRDLDRLISEETGLHVQVAD
DPLTCVARGGGRALELVDMHGNEFFAPE

Sequences:

>Translated_348_residues
MFKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGAEAKQMLGRTPGHITTIRPMKDG
VIADFTYTEAMLKHFIKKVHKSRFLRPSPRVLVCVPAGSTQVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEAR
GSMVIDIGGGTTEVAVISLNGIVYSQSVRVGGDRFDESITNYVRRNHGMLIGEATAERIKLQIGCAYPQDEVQEMEISGR
NLAEGVPKMIKINSNEVLEALHEPLSGIVSAVKLALEQTPPELCADVAERGIVLTGGGALLRDLDRLISEETGLHVQVAD
DPLTCVARGGGRALELVDMHGNEFFAPE
>Mature_348_residues
MFKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGAEAKQMLGRTPGHITTIRPMKDG
VIADFTYTEAMLKHFIKKVHKSRFLRPSPRVLVCVPAGSTQVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEAR
GSMVIDIGGGTTEVAVISLNGIVYSQSVRVGGDRFDESITNYVRRNHGMLIGEATAERIKLQIGCAYPQDEVQEMEISGR
NLAEGVPKMIKINSNEVLEALHEPLSGIVSAVKLALEQTPPELCADVAERGIVLTGGGALLRDLDRLISEETGLHVQVAD
DPLTCVARGGGRALELVDMHGNEFFAPE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=348, Percent_Identity=77.2988505747126, Blast_Score=555, Evalue=1e-159,
Organism=Saccharomyces cerevisiae, GI6324120, Length=242, Percent_Identity=26.4462809917355, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37398; Mature: 37398

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGAEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCHHHHHHHHH
KQMLGRTPGHITTIRPMKDGVIADFTYTEAMLKHFIKKVHKSRFLRPSPRVLVCVPAGST
HHHHCCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCH
QVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEARGSMVIDIGGGTTEVAVISLN
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GIVYSQSVRVGGDRFDESITNYVRRNHGMLIGEATAERIKLQIGCAYPQDEVQEMEISGR
CEEEECEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCHHHHHHHHCCCC
NLAEGVPKMIKINSNEVLEALHEPLSGIVSAVKLALEQTPPELCADVAERGIVLTGGGAL
CHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLISEETGLHVQVADDPLTCVARGGGRALELVDMHGNEFFAPE
HHHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEEECCCEECCCC
>Mature Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGAEA
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCCCCHHHHHHHHH
KQMLGRTPGHITTIRPMKDGVIADFTYTEAMLKHFIKKVHKSRFLRPSPRVLVCVPAGST
HHHHCCCCCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCH
QVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEARGSMVIDIGGGTTEVAVISLN
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEC
GIVYSQSVRVGGDRFDESITNYVRRNHGMLIGEATAERIKLQIGCAYPQDEVQEMEISGR
CEEEECEEECCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEECCCCHHHHHHHHCCCC
NLAEGVPKMIKINSNEVLEALHEPLSGIVSAVKLALEQTPPELCADVAERGIVLTGGGAL
CHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHH
LRDLDRLISEETGLHVQVADDPLTCVARGGGRALELVDMHGNEFFAPE
HHHHHHHHHHCCCCEEEECCCCEEEEECCCCCEEEEEEECCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]