Click here to switch to the map view.

The map label for this gene is ptrB [H]

Identifier: 21241402

GI number: 21241402

Start: 745904

End: 747976

Strand: Direct

Name: ptrB [H]

Synonym: XAC0631

Alternate gene names: 21241402

Gene position: 745904-747976 (Clockwise)

Preceding gene: 21241400

Following gene: 21241403

Centisome position: 14.41

GC content: 62.23

Gene sequence:

>2073_bases
ATGACCACTGTCCCTGCCTTCGCCGCCCTTCCGTCGCCGCCAGACGTTGCCAAGCACCCGCATGTGGTCAAGGCGCCGTT
CGGCGCGACCCGTAACGACGACTATTACTGGTTGCGCGACGACAAGCGCCAAGACAAGGCGATGCTGGCGTATCTCAACG
CCGAGAATGCCTACACCGACAAGGTGATGGCGCCGCTGAAACCCCTGGAAGAAGCGCTGTATACCGAGATCGTCGGGCGC
ATCAAGCAGGACGATGCCAGCGTGCCGTATCGCGAGCGCGGCTATTGGTATTACACGCGGTTCGAAACCGGCAAGGATTA
TCCGATCCAGGCGCGCCGCAAGGGCAGCATGGAGGCGCCGGAGGAGATCCTGCTCGACGTCAACCAGATGGCGCAGGGCA
AGGGCTACTTCAGCGTGGGCGATGCCGCGGTGAGCCAGGACAATCGCATCCTCGCCTGGGCCGACGATGCCGTTGGCCGC
CGTCAATACACCATCCGCTTCAAGAACCTGGAGACCGGCGAACTCTATCCGGACACGGTGGAGGGCGTCTCGGCCAATGT
GGTGTGGGCCGACGACAACAAGACGCTGTTCTATATCGAAAACGATCCGGAAACGCTGCTCACCGTGCGCGTGAAAAAGC
ACGTGCTGGGCACGCCGTCCAGGGACGATGCGCTGGTGTACGAAGAGAAGGACGACAGCTTCTACATGGGCATCGGCCGC
ACGCGCGACGACAAGTACATCACCATCGAGATGGAAAGCACGGTCTCTTCGGAAACCCGCTATGCGCTGGCCGCCAAGCC
GGACGCCTTCAAGGTGCTGGCCAGGCGCGAGCGCGATGTGGAATACCACGCCGAGCATTTCGATGGCCGCTGGGTGATTC
GCACCAATGCCGACAACGCCAGGAACTTCAAGCTGGTCACTGCGCCCACCGATGCGACCACACGCACGCATTGGACCGAC
TGGGTAGCGCACGACGACAACGTCTACATCGAAGACTTCGAATTGTTCGATGGATTCACCGCCATCGAAGAGCGTTCCGG
CGGACTGGAGCGTGTGCGCTTGCTCAAGCGCGATGGCAGCCATGAGTACGTCAAGGCCGACGAACCGGCGTATTCGATGG
GTCTATCCGTCAACTCCGAGCCGGATACCGCCTGGCTGCGCTACAGCTACACCTCGTTGACCACGCCGGGGACCACCTAC
GAGCTCAATACGCAGACCGGCGAGCGCAGGTTGCTCAAGCAACAACCGGTGATCGGCTACGACGCCAGCAAATACGTGAC
CGAACGCGTGTGGGTGACCGCGCGCGACGGGGTCAAGGTGCCGGTGTCGCTGGTGTACAAAAAGGGCTTCAAGAAGGACG
GCAGCGCAGCGCTGTTTCAATATGCGTACGGCAGTTACGGCATGTCGATGGACCCGGCATTCAATCTGCCGGCGATCAGC
CTGCTGGACCGCGGTGTGGTGTATGCCATCGCGCACATCCGCGGCGGCCAGGAAATGGGGCGCCAGTGGTACGACGATGG
CAAGCTGCTGCACAAGAAAAACACCTTCAATGACTTTATCGATGTCACCCGCGGTCTGGTCACCCAGGGGTACGCCGCCA
AGGACCGCGTTGCCGCATCCGGTGGTAGCGCCGGCGGCCTGCTGATGGGCGCGGTGGCCAACATGGCGCCGCAGGACTAT
CGCGTGATGGTCGCGCAGGTGCCGTTCGTCGATGTGGTCACCACCATGCTCGACGCCAGCATTCCGCTCACCACCAACGA
ATACGACGAGTGGGGCAACCCGGAAACCCAGGACTATTACGCGTACATGCTGTCGTACTCGCCGTACGACAACGTGCGCA
AGCAGGCGTACCCGGCGCTGTTCGTGGGCACCGGCCTGTGGGATTCGCAGGTGCAGTACTGGGAGCCGGCCAAGTGGGTG
GCCAAGCTGCGCGACGACAACACCGGCACCCAGCCGATCGTGTTCCGTACCAATATGGAAGCCGGGCATGGCGGCAAATC
CGGACGCTTCCGCCGCTACCGCGAGCTGGCCGAGTCGTATGCGTTCGTGCTGGATCAGCTGGGCGTGAAGTAG

Upstream 100 bases:

>100_bases
CAGAAGGCTCTTCCACACTCGGGTGCTGGGATGGCATTGCGTTCATCCAATGGACCCCAATCTGATGAAGCCCGTTCTCA
CTGTTCTGATCGCCAGCCTG

Downstream 100 bases:

>100_bases
CTGGAGGGTCGGGATTTGGGAGTCGGGATCTGGGATTGGTTGCAGCGGATGGCTTGGGCTGGAGCTGGCTGCTCGTTGGG
ATGCGATGGCTAGCCTCCCT

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MTTVPAFAALPSPPDVAKHPHVVKAPFGATRNDDYYWLRDDKRQDKAMLAYLNAENAYTDKVMAPLKPLEEALYTEIVGR
IKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMEAPEEILLDVNQMAQGKGYFSVGDAAVSQDNRILAWADDAVGR
RQYTIRFKNLETGELYPDTVEGVSANVVWADDNKTLFYIENDPETLLTVRVKKHVLGTPSRDDALVYEEKDDSFYMGIGR
TRDDKYITIEMESTVSSETRYALAAKPDAFKVLARRERDVEYHAEHFDGRWVIRTNADNARNFKLVTAPTDATTRTHWTD
WVAHDDNVYIEDFELFDGFTAIEERSGGLERVRLLKRDGSHEYVKADEPAYSMGLSVNSEPDTAWLRYSYTSLTTPGTTY
ELNTQTGERRLLKQQPVIGYDASKYVTERVWVTARDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPAFNLPAIS
LLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVTQGYAAKDRVAASGGSAGGLLMGAVANMAPQDY
RVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETQDYYAYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWV
AKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYRELAESYAFVLDQLGVK

Sequences:

>Translated_690_residues
MTTVPAFAALPSPPDVAKHPHVVKAPFGATRNDDYYWLRDDKRQDKAMLAYLNAENAYTDKVMAPLKPLEEALYTEIVGR
IKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMEAPEEILLDVNQMAQGKGYFSVGDAAVSQDNRILAWADDAVGR
RQYTIRFKNLETGELYPDTVEGVSANVVWADDNKTLFYIENDPETLLTVRVKKHVLGTPSRDDALVYEEKDDSFYMGIGR
TRDDKYITIEMESTVSSETRYALAAKPDAFKVLARRERDVEYHAEHFDGRWVIRTNADNARNFKLVTAPTDATTRTHWTD
WVAHDDNVYIEDFELFDGFTAIEERSGGLERVRLLKRDGSHEYVKADEPAYSMGLSVNSEPDTAWLRYSYTSLTTPGTTY
ELNTQTGERRLLKQQPVIGYDASKYVTERVWVTARDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPAFNLPAIS
LLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVTQGYAAKDRVAASGGSAGGLLMGAVANMAPQDY
RVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETQDYYAYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWV
AKLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYRELAESYAFVLDQLGVK
>Mature_689_residues
TTVPAFAALPSPPDVAKHPHVVKAPFGATRNDDYYWLRDDKRQDKAMLAYLNAENAYTDKVMAPLKPLEEALYTEIVGRI
KQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMEAPEEILLDVNQMAQGKGYFSVGDAAVSQDNRILAWADDAVGRR
QYTIRFKNLETGELYPDTVEGVSANVVWADDNKTLFYIENDPETLLTVRVKKHVLGTPSRDDALVYEEKDDSFYMGIGRT
RDDKYITIEMESTVSSETRYALAAKPDAFKVLARRERDVEYHAEHFDGRWVIRTNADNARNFKLVTAPTDATTRTHWTDW
VAHDDNVYIEDFELFDGFTAIEERSGGLERVRLLKRDGSHEYVKADEPAYSMGLSVNSEPDTAWLRYSYTSLTTPGTTYE
LNTQTGERRLLKQQPVIGYDASKYVTERVWVTARDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPAFNLPAISL
LDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVTQGYAAKDRVAASGGSAGGLLMGAVANMAPQDYR
VMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETQDYYAYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWVA
KLRDDNTGTQPIVFRTNMEAGHGGKSGRFRRYRELAESYAFVLDQLGVK

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=716, Percent_Identity=24.7206703910615, Blast_Score=202, Evalue=7e-52,
Organism=Homo sapiens, GI284172438, Length=511, Percent_Identity=26.027397260274, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI284172431, Length=511, Percent_Identity=26.027397260274, Blast_Score=169, Evalue=1e-41,
Organism=Homo sapiens, GI284172420, Length=511, Percent_Identity=26.027397260274, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI284172413, Length=511, Percent_Identity=26.027397260274, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI70778815, Length=511, Percent_Identity=26.027397260274, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI108860686, Length=331, Percent_Identity=27.190332326284, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI108860692, Length=214, Percent_Identity=33.1775700934579, Blast_Score=128, Evalue=2e-29,
Organism=Escherichia coli, GI1788150, Length=676, Percent_Identity=47.0414201183432, Blast_Score=619, Evalue=1e-178,
Organism=Drosophila melanogaster, GI221510989, Length=719, Percent_Identity=24.2002781641168, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24583414, Length=757, Percent_Identity=23.9101717305152, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78198; Mature: 78067

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVPAFAALPSPPDVAKHPHVVKAPFGATRNDDYYWLRDDKRQDKAMLAYLNAENAYTD
CCCCCCHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHH
KVMAPLKPLEEALYTEIVGRIKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMEAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCEEEEEEECCCCCCCCCHHCCCCCCCC
EEILLDVNQMAQGKGYFSVGDAAVSQDNRILAWADDAVGRRQYTIRFKNLETGELYPDTV
HHHHHHHHHHHCCCCCEEECCHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCC
EGVSANVVWADDNKTLFYIENDPETLLTVRVKKHVLGTPSRDDALVYEEKDDSFYMGIGR
CCCEEEEEEECCCCEEEEEECCCCEEEEEEEEHHHCCCCCCCCEEEEEECCCCEEEECCC
TRDDKYITIEMESTVSSETRYALAAKPDAFKVLARRERDVEYHAEHFDGRWVIRTNADNA
CCCCCEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCC
RNFKLVTAPTDATTRTHWTDWVAHDDNVYIEDFELFDGFTAIEERSGGLERVRLLKRDGS
CEEEEEECCCCCCCCCCCCEEEECCCCEEEEEEHHHCCHHHHHHHCCCHHHHHHHHCCCC
HEYVKADEPAYSMGLSVNSEPDTAWLRYSYTSLTTPGTTYELNTQTGERRLLKQQPVIGY
CCEEECCCCCCEECEECCCCCCCEEEEEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCC
DASKYVTERVWVTARDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPAFNLPAIS
CHHHHEEEEEEEEECCCCCCCHHHEEHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHH
LLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVTQGYAAKDRVAAS
HHHCCCEEEEEHHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCEECC
GGSAGGLLMGAVANMAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETQDYY
CCCCCCHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
AYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNME
EEEEEECCHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCC
AGHGGKSGRFRRYRELAESYAFVLDQLGVK
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTVPAFAALPSPPDVAKHPHVVKAPFGATRNDDYYWLRDDKRQDKAMLAYLNAENAYTD
CCCCCHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCEEEEEEECCCCCHH
KVMAPLKPLEEALYTEIVGRIKQDDASVPYRERGYWYYTRFETGKDYPIQARRKGSMEAP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCEEEEEEECCCCCCCCCHHCCCCCCCC
EEILLDVNQMAQGKGYFSVGDAAVSQDNRILAWADDAVGRRQYTIRFKNLETGELYPDTV
HHHHHHHHHHHCCCCCEEECCHHHCCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCC
EGVSANVVWADDNKTLFYIENDPETLLTVRVKKHVLGTPSRDDALVYEEKDDSFYMGIGR
CCCEEEEEEECCCCEEEEEECCCCEEEEEEEEHHHCCCCCCCCEEEEEECCCCEEEECCC
TRDDKYITIEMESTVSSETRYALAAKPDAFKVLARRERDVEYHAEHFDGRWVIRTNADNA
CCCCCEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCC
RNFKLVTAPTDATTRTHWTDWVAHDDNVYIEDFELFDGFTAIEERSGGLERVRLLKRDGS
CEEEEEECCCCCCCCCCCCEEEECCCCEEEEEEHHHCCHHHHHHHCCCHHHHHHHHCCCC
HEYVKADEPAYSMGLSVNSEPDTAWLRYSYTSLTTPGTTYELNTQTGERRLLKQQPVIGY
CCEEECCCCCCEECEECCCCCCCEEEEEEEEEECCCCCEEEEECCCCHHHHHHCCCCCCC
DASKYVTERVWVTARDGVKVPVSLVYKKGFKKDGSAALFQYAYGSYGMSMDPAFNLPAIS
CHHHHEEEEEEEEECCCCCCCHHHEEHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHH
LLDRGVVYAIAHIRGGQEMGRQWYDDGKLLHKKNTFNDFIDVTRGLVTQGYAAKDRVAAS
HHHCCCEEEEEHHCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCEECC
GGSAGGLLMGAVANMAPQDYRVMVAQVPFVDVVTTMLDASIPLTTNEYDEWGNPETQDYY
CCCCCCHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
AYMLSYSPYDNVRKQAYPALFVGTGLWDSQVQYWEPAKWVAKLRDDNTGTQPIVFRTNME
EEEEEECCHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCC
AGHGGKSGRFRRYRELAESYAFVLDQLGVK
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]