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The map label for this gene is adrA [H]

Identifier: 21241364

GI number: 21241364

Start: 696440

End: 698368

Strand: Direct

Name: adrA [H]

Synonym: XAC0593

Alternate gene names: 21241364

Gene position: 696440-698368 (Clockwise)

Preceding gene: 21241361

Following gene: 21241365

Centisome position: 13.46

GC content: 67.6

Gene sequence:

>1929_bases
ATGGCATCAGCTTGGCGTGCGCACGCTGCGGCCCGTCGTCGACGTGATGATGCGATGAGCATGTTCGTGGTCCGGTGGCG
ACAGGGGCTCGCCGCGTTTGCCTTGCTGCTGGGCAGTGGCATGGTGTCGGCGCAGCCGCAGCCGTGGAAGACGATCGAAG
CGGCGACCATCGACGACCCCGTGGTCGCGTTGCAGATCGCACAAGGCGCACTGCAGCGCGCTAGCGGCGACCACGACGTG
GATGCCGAGTTCTGGGCCTTGCTGGCGCAGGCGCGCGTGCTTATTTCACTGGAAGACAGCGAACGCCGCCAGGTGGCGCT
GACGCAGGCGCGCGGAAGGCTCGACCAGTTGCACGGCAACGCCTCGCAGGCGCAGCTGTGGCTGGACATCGTGCAGGCGC
TCAGCGATGTGCGCGAAAACCCCAATCGCGTCATGGTGGCGCGGTTGGAAGCGCTGCGCCAACGGGCCAGCGCGCTGGGC
CCCAACGATCTGCTGTGCGAAGTCGAGGCAATCGACATGTGGAGCATGCTCGCCTCCGGCAGCAGCGATGAGTCGTGGAA
CGCGGCGCAGGCCAGCTATCAATGTGCGGCGCGCGAAAAACTCCTGGGGCTGGAGCTGGACGCGTTGACGCAACTGGGGT
CATTGGCCAGCCGCGTCGGCGGTCGCGCCGCCGAAGACAACGAAACCGAAGACTACCTGCAGCGTGCGCTCGCACGCCTG
CACGACCAGCCGGCGCGCTTTCAGCGCAGTCTGATCGAATACGAGTTCGGCACTGCCTTGGCCACACGGCAACCCGAAGC
GGCGCTGCTGCATTTCAGGCGCGCGTTGGCGCTCAGTCGCGAACTGCGCGACCAGGCCGGCGTGGCTGCAGCGCTGACCA
GCGCCAGCGAGGCCCTGATCGAAACCGGCGATGCCGCTTCTGCATTGACGATGGCCCGCGAAGCCCTGCCGTTGATGCAG
CAACAAGGCAATATCGGGCGCGTCGCGGCGTGCCACGCCGTGTTGCTGCGGGCCTTGATCGCGTTGAAGGCTGAGGGTCT
GGACGCGGAAATCGTGGCTGCCAAGGCCGCAGACGACCCCAACCTGACCTTGCACCGGCGCGCGCAACTGGTGGACGCGA
TCGCCCAGGCGCTGGCGTCGCAAGGTCGCCATGCAGAGGCCTACCAGGAACTGCAACGCGCCAACGCGCTGCGCGCGCAT
AGCCTGGACCGCCAGCGCGATACGGTGATGTTGCGGTTGCAGGCGCGCTACGAAGATGCCCGCCGCGGCGCCGAAACGGC
CGAGCTGCGCCGCCGTAGCGAGACCGCGCAGCTGGCACTGCAGGCGCGCGAAGCCGGCCAGCGGGCGCTGTGGATCGCGT
TGTGCGCAGCCTGCCTGTTGTTGCTCGGTGCATTGGTGGTGCTGGCCTTCGGCGCACGGCACCGCCGCCAGCTATCGCGG
CTGGCGATGCGCGATGAACTCACCGGCCTGCCCAACCGGCGCGCCATTCGCACCGAGGCGCAGCAGCAGATCGAGCAGGC
CTTGCGCTCGCACACGCCGGGCATGCTGGCATTGATCGATCTGGATCACTTCAAGCAGATCAACGACGTGTATGGGCATG
CCACCGGCGATACGGTGCTCAAGGCGCTGGCCAGCGCATCGCGGCTGGCCCTGCGCGGGCAGGATCGCCTGGGCCGCCTG
GGCGGCGAAGAATTTCTGCTGGTGTTGCCGGGCTGTGGCGAAGAGGAGATTCCCACGGTGTTTACGCGCCTGCGTAGTGC
GGTGGCAGCGATCGACATCGCCGGCCTGCCGGCCGAGGAACCGGTACGCTTTTGCATGGGCGCGGTACGCATCGTCGCCG
ACACCGGGCTGGATGCGTTGCTGAGCCAGGCCGATCTTGCGCTATACGCCGCCAAGACCGCTGGGCGCGATCAGTGGGCG
GTGTGCTGA

Upstream 100 bases:

>100_bases
GATTGGCGTTTGGCCTGAAATTCCGCTGGACTCCATCGTCCTCCAACCGTGGGAGTGCTTGAAATGCCGCAGCAACCAGC
AAGCCGCCACGTAAGCGCAG

Downstream 100 bases:

>100_bases
TCCTGGTGTACGCACCTGCGCTGCGACATCGAGGCGATGCTGCGGCACAAGCTGCCGGCCGATGGCGACCGCTGGTTGCC
GTGAACCGATCGAACGACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MASAWRAHAAARRRRDDAMSMFVVRWRQGLAAFALLLGSGMVSAQPQPWKTIEAATIDDPVVALQIAQGALQRASGDHDV
DAEFWALLAQARVLISLEDSERRQVALTQARGRLDQLHGNASQAQLWLDIVQALSDVRENPNRVMVARLEALRQRASALG
PNDLLCEVEAIDMWSMLASGSSDESWNAAQASYQCAAREKLLGLELDALTQLGSLASRVGGRAAEDNETEDYLQRALARL
HDQPARFQRSLIEYEFGTALATRQPEAALLHFRRALALSRELRDQAGVAAALTSASEALIETGDAASALTMAREALPLMQ
QQGNIGRVAACHAVLLRALIALKAEGLDAEIVAAKAADDPNLTLHRRAQLVDAIAQALASQGRHAEAYQELQRANALRAH
SLDRQRDTVMLRLQARYEDARRGAETAELRRRSETAQLALQAREAGQRALWIALCAACLLLLGALVVLAFGARHRRQLSR
LAMRDELTGLPNRRAIRTEAQQQIEQALRSHTPGMLALIDLDHFKQINDVYGHATGDTVLKALASASRLALRGQDRLGRL
GGEEFLLVLPGCGEEEIPTVFTRLRSAVAAIDIAGLPAEEPVRFCMGAVRIVADTGLDALLSQADLALYAAKTAGRDQWA
VC

Sequences:

>Translated_642_residues
MASAWRAHAAARRRRDDAMSMFVVRWRQGLAAFALLLGSGMVSAQPQPWKTIEAATIDDPVVALQIAQGALQRASGDHDV
DAEFWALLAQARVLISLEDSERRQVALTQARGRLDQLHGNASQAQLWLDIVQALSDVRENPNRVMVARLEALRQRASALG
PNDLLCEVEAIDMWSMLASGSSDESWNAAQASYQCAAREKLLGLELDALTQLGSLASRVGGRAAEDNETEDYLQRALARL
HDQPARFQRSLIEYEFGTALATRQPEAALLHFRRALALSRELRDQAGVAAALTSASEALIETGDAASALTMAREALPLMQ
QQGNIGRVAACHAVLLRALIALKAEGLDAEIVAAKAADDPNLTLHRRAQLVDAIAQALASQGRHAEAYQELQRANALRAH
SLDRQRDTVMLRLQARYEDARRGAETAELRRRSETAQLALQAREAGQRALWIALCAACLLLLGALVVLAFGARHRRQLSR
LAMRDELTGLPNRRAIRTEAQQQIEQALRSHTPGMLALIDLDHFKQINDVYGHATGDTVLKALASASRLALRGQDRLGRL
GGEEFLLVLPGCGEEEIPTVFTRLRSAVAAIDIAGLPAEEPVRFCMGAVRIVADTGLDALLSQADLALYAAKTAGRDQWA
VC
>Mature_641_residues
ASAWRAHAAARRRRDDAMSMFVVRWRQGLAAFALLLGSGMVSAQPQPWKTIEAATIDDPVVALQIAQGALQRASGDHDVD
AEFWALLAQARVLISLEDSERRQVALTQARGRLDQLHGNASQAQLWLDIVQALSDVRENPNRVMVARLEALRQRASALGP
NDLLCEVEAIDMWSMLASGSSDESWNAAQASYQCAAREKLLGLELDALTQLGSLASRVGGRAAEDNETEDYLQRALARLH
DQPARFQRSLIEYEFGTALATRQPEAALLHFRRALALSRELRDQAGVAAALTSASEALIETGDAASALTMAREALPLMQQ
QGNIGRVAACHAVLLRALIALKAEGLDAEIVAAKAADDPNLTLHRRAQLVDAIAQALASQGRHAEAYQELQRANALRAHS
LDRQRDTVMLRLQARYEDARRGAETAELRRRSETAQLALQAREAGQRALWIALCAACLLLLGALVVLAFGARHRRQLSRL
AMRDELTGLPNRRAIRTEAQQQIEQALRSHTPGMLALIDLDHFKQINDVYGHATGDTVLKALASASRLALRGQDRLGRLG
GEEFLLVLPGCGEEEIPTVFTRLRSAVAAIDIAGLPAEEPVRFCMGAVRIVADTGLDALLSQADLALYAAKTAGRDQWAV
C

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=34.5238095238095, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=36.1290322580645, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1788381, Length=163, Percent_Identity=39.2638036809816, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=38.0952380952381, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787816, Length=156, Percent_Identity=32.6923076923077, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=32.9411764705882, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=35.4037267080745, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787541, Length=171, Percent_Identity=32.7485380116959, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI87081974, Length=117, Percent_Identity=35.8974358974359, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=153, Percent_Identity=32.6797385620915, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788956, Length=165, Percent_Identity=33.9393939393939, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 69873; Mature: 69741

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAWRAHAAARRRRDDAMSMFVVRWRQGLAAFALLLGSGMVSAQPQPWKTIEAATIDDP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCH
VVALQIAQGALQRASGDHDVDAEFWALLAQARVLISLEDSERRQVALTQARGRLDQLHGN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHCCC
ASQAQLWLDIVQALSDVRENPNRVMVARLEALRQRASALGPNDLLCEVEAIDMWSMLASG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHHCC
SSDESWNAAQASYQCAAREKLLGLELDALTQLGSLASRVGGRAAEDNETEDYLQRALARL
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HDQPARFQRSLIEYEFGTALATRQPEAALLHFRRALALSRELRDQAGVAAALTSASEALI
CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGDAASALTMAREALPLMQQQGNIGRVAACHAVLLRALIALKAEGLDAEIVAAKAADDP
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCC
NLTLHRRAQLVDAIAQALASQGRHAEAYQELQRANALRAHSLDRQRDTVMLRLQARYEDA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
RRGAETAELRRRSETAQLALQAREAGQRALWIALCAACLLLLGALVVLAFGARHRRQLSR
HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LAMRDELTGLPNRRAIRTEAQQQIEQALRSHTPGMLALIDLDHFKQINDVYGHATGDTVL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCHHHHH
KALASASRLALRGQDRLGRLGGEEFLLVLPGCGEEEIPTVFTRLRSAVAAIDIAGLPAEE
HHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
PVRFCMGAVRIVADTGLDALLSQADLALYAAKTAGRDQWAVC
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASAWRAHAAARRRRDDAMSMFVVRWRQGLAAFALLLGSGMVSAQPQPWKTIEAATIDDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCH
VVALQIAQGALQRASGDHDVDAEFWALLAQARVLISLEDSERRQVALTQARGRLDQLHGN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHCCC
ASQAQLWLDIVQALSDVRENPNRVMVARLEALRQRASALGPNDLLCEVEAIDMWSMLASG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHHCC
SSDESWNAAQASYQCAAREKLLGLELDALTQLGSLASRVGGRAAEDNETEDYLQRALARL
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
HDQPARFQRSLIEYEFGTALATRQPEAALLHFRRALALSRELRDQAGVAAALTSASEALI
CCCHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETGDAASALTMAREALPLMQQQGNIGRVAACHAVLLRALIALKAEGLDAEIVAAKAADDP
HCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCCC
NLTLHRRAQLVDAIAQALASQGRHAEAYQELQRANALRAHSLDRQRDTVMLRLQARYEDA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHH
RRGAETAELRRRSETAQLALQAREAGQRALWIALCAACLLLLGALVVLAFGARHRRQLSR
HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LAMRDELTGLPNRRAIRTEAQQQIEQALRSHTPGMLALIDLDHFKQINDVYGHATGDTVL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCHHHHH
KALASASRLALRGQDRLGRLGGEEFLLVLPGCGEEEIPTVFTRLRSAVAAIDIAGLPAEE
HHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
PVRFCMGAVRIVADTGLDALLSQADLALYAAKTAGRDQWAVC
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]