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The map label for this gene is prmA

Identifier: 21241297

GI number: 21241297

Start: 616029

End: 616949

Strand: Reverse

Name: prmA

Synonym: XAC0526

Alternate gene names: 21241297

Gene position: 616949-616029 (Counterclockwise)

Preceding gene: 21241301

Following gene: 21241295

Centisome position: 11.92

GC content: 67.43

Gene sequence:

>921_bases
ATGCCGTTTCTTGAACTGACGCTTTCCTGTTCCGAGGTCACCCTGCCCCGTTTCCAGAATGCACTGGACGATGTGGGCGC
ACTGGCGGTGACCATGCTCGACGCCGATGCCGATACCAGCAACGAGCGCGCCATTCTCGAACCCGGTGTGGGCGAGATGC
CGCTGTGGGACCGACTGACGATGACCGCGCTGTTCGATGGCGACAGCGACGCGCTGGTGGTGCTGGCGGCGCTGGAAGCC
TTCGATCCGGGCCTGGACTGGAGCCAGGTGGCGTTTCGTATGGTCGAAGACAGCGACTGGGAACGTGCCTGGATGGACCT
GTTCAAGCCGATGCAGTTTGGCGAACGCACCTTTATCGTGCCGTGGAATCACGCGCTGCCCGAAGCCGCGGACACCCCGG
AAGCCGCCGTGGTGCGGCTGGACCCGGGCCTGGCATTCGGCTCGGGCACCCATCAAACCACCGCGCTGTGCCTGCGCTGG
CTGGACAGCCTGGCCGGCAGCGGCGAGCTGCAGGGCCGCAGCGTGCTCGATTTCGGATGTGGCTCGGGCATCCTGGCGGT
CGCCGCGCTGAAGCTGGGCGCCACCCACGCGGTCGGCGTGGACAACGACCCGCAGGCACTGCTGGCGACCGCCGACAATG
CGCAACGCAACGGCGTGGACGCCCAGCTGGCGGTCTACATGCCGCAGGACGAACCGGTGCAGACCTACCAGGTGGTGGTG
GCCAACATCCTGGCCTCGGCACTGGACGCCCTGGCCGACACCCTGGCCGCGCGCGTGGCACCGGGCGGACGGATTGCGCT
GTCGGGCATCCTGCACGGCCAGGAAGACGACTTGCTGAAACGCTACGCCCCCTGGTTCGAACAGTTGCGCTGCGAACGCG
ACGAAGACTGGATGCGGATCGACGGCGTGCGCCGCGGCTGA

Upstream 100 bases:

>100_bases
CGGAGCCGACGGCGCCTGCGAATGCAATCGCCTGTAGAGCGGCAGGCACGCCGGCACGAATGGTCTAGGATGCGTGGTTT
CGAATTGCCCGACCGCCCCG

Downstream 100 bases:

>100_bases
TCCAGCACGTCATCCACGCCGGCTAGCGCTGTGGCCGGCCGGCGCGGATCTGCGCGGTAGTCACTGCATCGGCCACGCTG
ATCGCCCGTAACCGGGTCAC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPFLELTLSCSEVTLPRFQNALDDVGALAVTMLDADADTSNERAILEPGVGEMPLWDRLTMTALFDGDSDALVVLAALEA
FDPGLDWSQVAFRMVEDSDWERAWMDLFKPMQFGERTFIVPWNHALPEAADTPEAAVVRLDPGLAFGSGTHQTTALCLRW
LDSLAGSGELQGRSVLDFGCGSGILAVAALKLGATHAVGVDNDPQALLATADNAQRNGVDAQLAVYMPQDEPVQTYQVVV
ANILASALDALADTLAARVAPGGRIALSGILHGQEDDLLKRYAPWFEQLRCERDEDWMRIDGVRRG

Sequences:

>Translated_306_residues
MPFLELTLSCSEVTLPRFQNALDDVGALAVTMLDADADTSNERAILEPGVGEMPLWDRLTMTALFDGDSDALVVLAALEA
FDPGLDWSQVAFRMVEDSDWERAWMDLFKPMQFGERTFIVPWNHALPEAADTPEAAVVRLDPGLAFGSGTHQTTALCLRW
LDSLAGSGELQGRSVLDFGCGSGILAVAALKLGATHAVGVDNDPQALLATADNAQRNGVDAQLAVYMPQDEPVQTYQVVV
ANILASALDALADTLAARVAPGGRIALSGILHGQEDDLLKRYAPWFEQLRCERDEDWMRIDGVRRG
>Mature_305_residues
PFLELTLSCSEVTLPRFQNALDDVGALAVTMLDADADTSNERAILEPGVGEMPLWDRLTMTALFDGDSDALVVLAALEAF
DPGLDWSQVAFRMVEDSDWERAWMDLFKPMQFGERTFIVPWNHALPEAADTPEAAVVRLDPGLAFGSGTHQTTALCLRWL
DSLAGSGELQGRSVLDFGCGSGILAVAALKLGATHAVGVDNDPQALLATADNAQRNGVDAQLAVYMPQDEPVQTYQVVVA
NILASALDALADTLAARVAPGGRIALSGILHGQEDDLLKRYAPWFEQLRCERDEDWMRIDGVRRG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=306, Percent_Identity=43.4640522875817, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_XANAC (Q8PQ06)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_640879.1
- ProteinModelPortal:   Q8PQ06
- GeneID:   1154597
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0526
- NMPDR:   fig|190486.1.peg.523
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- ProtClustDB:   PRK00517
- BioCyc:   XAXO190486:XAC0526-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33125; Mature: 32994

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFLELTLSCSEVTLPRFQNALDDVGALAVTMLDADADTSNERAILEPGVGEMPLWDRLT
CCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEECCCCCCCCCHHHEE
MTALFDGDSDALVVLAALEAFDPGLDWSQVAFRMVEDSDWERAWMDLFKPMQFGERTFIV
EEEEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEE
PWNHALPEAADTPEAAVVRLDPGLAFGSGTHQTTALCLRWLDSLAGSGELQGRSVLDFGC
ECCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
GSGILAVAALKLGATHAVGVDNDPQALLATADNAQRNGVDAQLAVYMPQDEPVQTYQVVV
CCHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHH
ANILASALDALADTLAARVAPGGRIALSGILHGQEDDLLKRYAPWFEQLRCERDEDWMRI
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEE
DGVRRG
CCCCCC
>Mature Secondary Structure 
PFLELTLSCSEVTLPRFQNALDDVGALAVTMLDADADTSNERAILEPGVGEMPLWDRLT
CCEEEEECCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEECCCCCCCCCHHHEE
MTALFDGDSDALVVLAALEAFDPGLDWSQVAFRMVEDSDWERAWMDLFKPMQFGERTFIV
EEEEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEE
PWNHALPEAADTPEAAVVRLDPGLAFGSGTHQTTALCLRWLDSLAGSGELQGRSVLDFGC
ECCCCCCCCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCC
GSGILAVAALKLGATHAVGVDNDPQALLATADNAQRNGVDAQLAVYMPQDEPVQTYQVVV
CCHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHH
ANILASALDALADTLAARVAPGGRIALSGILHGQEDDLLKRYAPWFEQLRCERDEDWMRI
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEE
DGVRRG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217