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The map label for this gene is cdsA [H]

Identifier: 21241292

GI number: 21241292

Start: 611816

End: 612748

Strand: Direct

Name: cdsA [H]

Synonym: XAC0521

Alternate gene names: 21241292

Gene position: 611816-612748 (Clockwise)

Preceding gene: 21241291

Following gene: 21241296

Centisome position: 11.82

GC content: 63.13

Gene sequence:

>933_bases
ATGCATCAGCAGACGCTGTGGCTGTTCAGCGGTATCGCGCTGGTGCTCATCATCGCCACGCTGATTTCCGAAACCCTGCG
TTGGCGCGCACGCGAACGCCCCAGCGCAGTGCTGGACAACCTGGTCGCCCGCATCCGTGCGTGGTGGGTGATGGCCGCGG
TGGTCGGCCTTGCGTTCGTGTTTGGCCGCGCCGGCGTCATCGGCTTGTTCGCGTTGGTGTCGTTGTTTGCGCTGCGCGAG
TTCATCACCTTGACCCCGACCCGGCGCGGCGATTACTACGCGTTACTGGCCGCGTTCTACGTCGTGTTACCGTGGCAATA
CGGCCTGGTGTGGACCGGCTGGTACGGCCTGTACACCTTGCTGATTCCGGTCTACGCGTTCCTGGTATTGCCGATCCTGG
CCACCATCGGCGGCGACACCACGCGTTATCTGGAACGCACCGCCAAAGTGCAGTGGGGCCTGATGATCTGCGTGTTCTGC
ATTTCGCATGTGCCGGCGCTGTTGAACCTGGACATTCCCGGCTATGCGGGGCGCAATCTGCTGTTGATCGCCTTCCTGGT
GATCGTGGTGCAGTCCTCGGACGTACTGCAGTACGTGTGGGGCAAACTGGCCGGCCGCCATCTGATCGCGCCGAAATTGT
CGCCGTCCAAAACGGTGGAAGGATTCATCGGCGGCGTGGTGTCGGCCAGCCTGCTCGGGATGGCGCTGTGGTGGATCACC
CCGTTCGCGCCGTGGCATGCCTTCGGCCTGGCATTGGTGGCCAACCTGATGGGATTTTTCGGCGGGCTGGTGATGTCGGC
GATCAAGCGCGATCGCGGCATCAAGGACTGGGGCCATATGATCGAAGGCCACGGCGGTGTGCTCGACCGCCTGGATTCGG
TGTGCTTCGCCGCGCCGGTCTTCTTCCACCTGATTCGCTATGGCTGGGCGTGA

Upstream 100 bases:

>100_bases
TGACGCGTGCACGTGCGGCGTTGCTGGCGTTGTCGCCGGATCACTTGGAGGCGCGCGCATGAGCCTGTCTGCGTACAGCG
GCCAGCTGCAGCAGTCTTCG

Downstream 100 bases:

>100_bases
CCGCTTGTCACATCGCTTGTCATGAAATCGCAACACGTGCATCGCGTGCCGTTGGCGATCTGCAGCACCGGATCCGCCCA
GCGCGCGTCGGTCAACCGCC

Product: phosphatidate cytidiltransferase

Products: diphosphate; CDPdiacylglycerol

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MHQQTLWLFSGIALVLIIATLISETLRWRARERPSAVLDNLVARIRAWWVMAAVVGLAFVFGRAGVIGLFALVSLFALRE
FITLTPTRRGDYYALLAAFYVVLPWQYGLVWTGWYGLYTLLIPVYAFLVLPILATIGGDTTRYLERTAKVQWGLMICVFC
ISHVPALLNLDIPGYAGRNLLLIAFLVIVVQSSDVLQYVWGKLAGRHLIAPKLSPSKTVEGFIGGVVSASLLGMALWWIT
PFAPWHAFGLALVANLMGFFGGLVMSAIKRDRGIKDWGHMIEGHGGVLDRLDSVCFAAPVFFHLIRYGWA

Sequences:

>Translated_310_residues
MHQQTLWLFSGIALVLIIATLISETLRWRARERPSAVLDNLVARIRAWWVMAAVVGLAFVFGRAGVIGLFALVSLFALRE
FITLTPTRRGDYYALLAAFYVVLPWQYGLVWTGWYGLYTLLIPVYAFLVLPILATIGGDTTRYLERTAKVQWGLMICVFC
ISHVPALLNLDIPGYAGRNLLLIAFLVIVVQSSDVLQYVWGKLAGRHLIAPKLSPSKTVEGFIGGVVSASLLGMALWWIT
PFAPWHAFGLALVANLMGFFGGLVMSAIKRDRGIKDWGHMIEGHGGVLDRLDSVCFAAPVFFHLIRYGWA
>Mature_310_residues
MHQQTLWLFSGIALVLIIATLISETLRWRARERPSAVLDNLVARIRAWWVMAAVVGLAFVFGRAGVIGLFALVSLFALRE
FITLTPTRRGDYYALLAAFYVVLPWQYGLVWTGWYGLYTLLIPVYAFLVLPILATIGGDTTRYLERTAKVQWGLMICVFC
ISHVPALLNLDIPGYAGRNLLLIAFLVIVVQSSDVLQYVWGKLAGRHLIAPKLSPSKTVEGFIGGVVSASLLGMALWWIT
PFAPWHAFGLALVANLMGFFGGLVMSAIKRDRGIKDWGHMIEGHGGVLDRLDSVCFAAPVFFHLIRYGWA

Specific function: Unknown

COG id: COG4589

COG function: function code R; Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI1787677, Length=296, Percent_Identity=38.8513513513513, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87081696, Length=135, Percent_Identity=43.7037037037037, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: 2.7.7.41

Molecular weight: Translated: 34425; Mature: 34425

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQQTLWLFSGIALVLIIATLISETLRWRARERPSAVLDNLVARIRAWWVMAAVVGLAFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRAGVIGLFALVSLFALREFITLTPTRRGDYYALLAAFYVVLPWQYGLVWTGWYGLYTL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LIPVYAFLVLPILATIGGDTTRYLERTAKVQWGLMICVFCISHVPALLNLDIPGYAGRNL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHH
LLIAFLVIVVQSSDVLQYVWGKLAGRHLIAPKLSPSKTVEGFIGGVVSASLLGMALWWIT
HHHHHHHHHHCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
PFAPWHAFGLALVANLMGFFGGLVMSAIKRDRGIKDWGHMIEGHGGVLDRLDSVCFAAPV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHH
FFHLIRYGWA
HHHHHHHCCC
>Mature Secondary Structure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HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; phosphatidate

Specific reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503; 9097039 [H]