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The map label for this gene is erpA

Identifier: 21241270

GI number: 21241270

Start: 586397

End: 586783

Strand: Direct

Name: erpA

Synonym: XAC0499

Alternate gene names: 21241270

Gene position: 586397-586783 (Clockwise)

Preceding gene: 21241269

Following gene: 21241272

Centisome position: 11.33

GC content: 63.82

Gene sequence:

>387_bases
ATGAGTACGCTCGTTTCGCTTCCTACTGCCGCCCCGGCGCCGGACTACCAGTCCATCGACCGGCCACTGAACTTTTCCGT
GGCCGCTGCCGCCAAGGTGCGCGAGCTGATCCAGGAAGAAGGCAATGCCGACCTGGCATTGCGCGTGTACATCCAGGGCG
GAGGGTGTTCCGGCTTCCAGTACGGCTTCGAGTTCGACGAGAACCGTGCCGAGGACGACCTGGCCGTGGCCACCGATGGC
GTCACGCTGCTGGTGGATCCGCTGAGCCTGCAATACCTGATGGGCGCCGAGGTGGATTACACCGAGAGCCTGACCGGCGC
GCAGTTCGTGATCCGCAATCCGAACGCAAAAACCACCTGCGGGTGCGGGAGCAGCTTCAGCGTCTGA

Upstream 100 bases:

>100_bases
AAACCGCCGACGCCTGAGCGCGGCATGCGCAGTGAATGCCGCGGCAGCCGATAAGGCGGCATGGCTTGAAGTGGGGCCCT
CTGGCCCCCATGCTGGCGCC

Downstream 100 bases:

>100_bases
TTGCATCTGGGTAGATGCGGATTGTGCGACGCATCTGGGTGAACGCGGATTGCGGCGCGTAGCGCGTGCTTCTGCAGTGC
ATCTGCGTTGGTGACAGGGT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MSTLVSLPTAAPAPDYQSIDRPLNFSVAAAAKVRELIQEEGNADLALRVYIQGGGCSGFQYGFEFDENRAEDDLAVATDG
VTLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTCGCGSSFSV

Sequences:

>Translated_128_residues
MSTLVSLPTAAPAPDYQSIDRPLNFSVAAAAKVRELIQEEGNADLALRVYIQGGGCSGFQYGFEFDENRAEDDLAVATDG
VTLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTCGCGSSFSV
>Mature_127_residues
STLVSLPTAAPAPDYQSIDRPLNFSVAAAAKVRELIQEEGNADLALRVYIQGGGCSGFQYGFEFDENRAEDDLAVATDGV
TLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=32.0754716981132, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=44.578313253012, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786351, Length=107, Percent_Identity=62.6168224299065, Blast_Score=147, Evalue=2e-37,
Organism=Escherichia coli, GI1788877, Length=106, Percent_Identity=35.8490566037736, Blast_Score=72, Evalue=8e-15,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=33.0188679245283, Blast_Score=66, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=34.9056603773585, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=34.9056603773585, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71998452, Length=111, Percent_Identity=36.9369369369369, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=82, Percent_Identity=37.8048780487805, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=34.9056603773585, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_XANAC (Q8PQ32)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_640852.1
- HSSP:   O67709
- ProteinModelPortal:   Q8PQ32
- SMR:   Q8PQ32
- GeneID:   1154570
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC0499
- NMPDR:   fig|190486.1.peg.496
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- BioCyc:   XAXO190486:XAC0499-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13605; Mature: 13474

Theoretical pI: Translated: 3.87; Mature: 3.87

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLVSLPTAAPAPDYQSIDRPLNFSVAAAAKVRELIQEEGNADLALRVYIQGGGCSGFQ
CCCEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
YGFEFDENRAEDDLAVATDGVTLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTC
CCCCCCCCCCCCCEEEEECCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCEE
GCGSSFSV
CCCCCCCC
>Mature Secondary Structure 
STLVSLPTAAPAPDYQSIDRPLNFSVAAAAKVRELIQEEGNADLALRVYIQGGGCSGFQ
CCEECCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
YGFEFDENRAEDDLAVATDGVTLLVDPLSLQYLMGAEVDYTESLTGAQFVIRNPNAKTTC
CCCCCCCCCCCCCEEEEECCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCCCEE
GCGSSFSV
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217