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The map label for this gene is sugE [H]

Identifier: 21241258

GI number: 21241258

Start: 575289

End: 575603

Strand: Direct

Name: sugE [H]

Synonym: XAC0485

Alternate gene names: 21241258

Gene position: 575289-575603 (Clockwise)

Preceding gene: 21241257

Following gene: 21241260

Centisome position: 11.12

GC content: 62.54

Gene sequence:

>315_bases
ATGCCCTGGATCCATCTGTTGCTGGCCGGCCTGTTCGAGATCGGCTTTGCCATGGGACTGAAATACAGCGACGGTTTCAC
TCGCCTGTGGCCGACCGTGCTGACAATCGGCCTTGCCGGCATCAGCCTGTGGTTTCTGACGCAGGCGCTGAAGACCATTC
CGGTCGGCACCGGCTATGCGATCTGGACCGGCATCGGTGCCTTGGGCGTGACCATTGCCGGTATCGCGCTATTCGGCGAT
AGCGCCTCGTGGTCGCGATTGGCGTGCATCGGTCTGATCGTGGCCGGGGTGATCGGGCTGAAGCTGGTCGGGTAG

Upstream 100 bases:

>100_bases
CCGCCACGCGATGACCTCGCGTTCCACAGCCGACGGCGGCCCAGTGTGCAAACACTGGGTCGCTTTTTTTTTGCCCATTT
TTTCTGTGAGGAGTACTGCA

Downstream 100 bases:

>100_bases
TCAGTCCCCCAGCGTTTGCTGCGCAAATCCCGGGCTCCGACTTGGAGGCTGCCTATCGCCACGCCTTTGGCGCGCCCCCT
CAACAAAGGGGGCTTGCTTC

Product: SugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MPWIHLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGISLWFLTQALKTIPVGTGYAIWTGIGALGVTIAGIALFGD
SASWSRLACIGLIVAGVIGLKLVG

Sequences:

>Translated_104_residues
MPWIHLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGISLWFLTQALKTIPVGTGYAIWTGIGALGVTIAGIALFGD
SASWSRLACIGLIVAGVIGLKLVG
>Mature_103_residues
PWIHLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGISLWFLTQALKTIPVGTGYAIWTGIGALGVTIAGIALFGDS
ASWSRLACIGLIVAGVIGLKLVG

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=54.9019607843137, Blast_Score=107, Evalue=1e-25,
Organism=Escherichia coli, GI1786755, Length=103, Percent_Identity=38.8349514563107, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10862; Mature: 10731

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIHLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGISLWFLTQALKTIPVGTGYA
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGALGVTIAGIALFGDSASWSRLACIGLIVAGVIGLKLVG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PWIHLLLAGLFEIGFAMGLKYSDGFTRLWPTVLTIGLAGISLWFLTQALKTIPVGTGYA
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWTGIGALGVTIAGIALFGDSASWSRLACIGLIVAGVIGLKLVG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12644504; 11677608 [H]