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The map label for this gene is clp [H]

Identifier: 21241256

GI number: 21241256

Start: 573528

End: 574220

Strand: Reverse

Name: clp [H]

Synonym: XAC0483

Alternate gene names: 21241256

Gene position: 574220-573528 (Counterclockwise)

Preceding gene: 21241259

Following gene: 77748528

Centisome position: 11.09

GC content: 63.35

Gene sequence:

>693_bases
ATGAGCCCAGGAAATACGACGGTTGTCACTACGACGGTACGTAACGCTACCCCCTCCCTGGCGCTGGACGCGGGCACCAT
CGAGCGTTTCCTGGCGCACAGCCACCGAAGACGCTATCCGACCCGGACCGATGTGTTCCGGCCAGGAGACCCGGCCGGCA
CCCTCTACTACGTGATCAGCGGCTCGGTAAGCATCATCGCCGAGGAAGATGACGACCGTGAGTTGGTGCTGGGCTACTTC
GGTAGCGGCGAATTCGTCGGTGAGATGGGGCTATTCATCGAATCCGACACCCGCGAGGTGATCCTGCGCACCCGCACCCA
GTGCGAGCTTGCCGAGATCAGCTACGAGCGGCTGCAGCAGCTGTTCCAGACCAGCCTGTCGCCGGATGCGCCGAAAATCC
TGTATGCGATCGGTGTTCAGCTTTCAAAACGGCTGCTCGATACCACAAGGAAAGCCAGCCGCCTGGCCTTCCTCGACGTG
ACCGACCGCATCGTGCGCACGCTGCACGACCTGGCCAAAGAGCCCGAAGCGATGAGCCATCCGCAGGGCACCCAGCTGCG
TGTTTCGCGCCAGGAACTTGCACGCCTGGTGGGGTGCTCACGCGAAATGGCTGGCCGCGTGCTCAAGAAGTTGCAGGCCG
ACGGCCTGCTGCACGCACGCGGCAAGACCGTCGTGCTGTACGGCACCCGCTGA

Upstream 100 bases:

>100_bases
TTATGAGCCAAAGATCCCAGCAACGAAATGCCGATGTTAAGAGTGGTTTACCTTGCATGACTCATGCCGTTAAGCTTCAG
GAATCACACGCGGAACTACC

Downstream 100 bases:

>100_bases
CGGCGCTGTGCAGCCCGTGCCTTGTGCACTGGCTGCATGCCGGGTTCGGCACCGGTCGATTCGATTGCGACGGTGCCGAC
ATCGGCAGTTTCATGACCTC

Product: cAMP-regulatory protein

Products: NA

Alternate protein names: CAP-like [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSPGNTTVVTTTVRNATPSLALDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYF
GSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPKILYAIGVQLSKRLLDTTRKASRLAFLDV
TDRIVRTLHDLAKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR

Sequences:

>Translated_230_residues
MSPGNTTVVTTTVRNATPSLALDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYF
GSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPKILYAIGVQLSKRLLDTTRKASRLAFLDV
TDRIVRTLHDLAKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
>Mature_229_residues
SPGNTTVVTTTVRNATPSLALDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYFG
SGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQTSLSPDAPKILYAIGVQLSKRLLDTTRKASRLAFLDVT
DRIVRTLHDLAKEPEAMSHPQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR

Specific function: Involved in the regulation of phytopathogenicity. It controls the production of extracellular enzymes, xanthan gum, and pigment either positively or negatively [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=205, Percent_Identity=45.8536585365854, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25622; Mature: 25490

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPGNTTVVTTTVRNATPSLALDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVIS
CCCCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
GSVSIIAEEDDDRELVLGYFGSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQ
CCEEEEEECCCCCEEEEEECCCCCEEEEECEEEECCCHHHHHHHCCHHHHHHHHHHHHHH
LFQTSLSPDAPKILYAIGVQLSKRLLDTTRKASRLAFLDVTDRIVRTLHDLAKEPEAMSH
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCCCHHCC
PQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
CCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCEEEEEECC
>Mature Secondary Structure 
SPGNTTVVTTTVRNATPSLALDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVIS
CCCCCEEEEEEECCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
GSVSIIAEEDDDRELVLGYFGSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQ
CCEEEEEECCCCCEEEEEECCCCCEEEEECEEEECCCHHHHHHHCCHHHHHHHHHHHHHH
LFQTSLSPDAPKILYAIGVQLSKRLLDTTRKASRLAFLDVTDRIVRTLHDLAKEPEAMSH
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCCCHHCC
PQGTQLRVSRQELARLVGCSREMAGRVLKKLQADGLLHARGKTVVLYGTR
CCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2170330; 1322886; 12024217 [H]