Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 21241158

GI number: 21241158

Start: 455227

End: 456009

Strand: Reverse

Name: fabG [H]

Synonym: XAC0384

Alternate gene names: 21241158

Gene position: 456009-455227 (Counterclockwise)

Preceding gene: 21241159

Following gene: 21241157

Centisome position: 8.81

GC content: 68.71

Gene sequence:

>783_bases
ATGGATCTGGGAATCGCTGGCCGCTGGGCGTTGGTCTGCGCCGCAAGCAAAGGGCTGGGTCTGGGCTGCGCACGTGCATT
GGCCGGCGAAGGCGGCAATGTGGTGATCGCCGCGCGCGGCCGTGAGGCACTGGAGCACGCCGCCGATGCCTTGCGCGCAT
TGCCCGGCTCTGGCGAAGTGCGCTGCGTGGTTGCCGATATCGCCACGCCGGAAGGGCGCAGCGCCGCACTCGCGGCCTGC
CCGCAGGTCGACATCCTGATCAACAACGCGGGCGGCCCGCCGCCAGGCGATTTCCGCCAGTGGGAACGCGCCGACTGGTT
GCGCGCGCTGGACGCCAACATGCTGGCGCCGATCGAACTGATCCGCGCCACCGTCGATGGCATGCGCGCACGCCGCTTCG
GCCGCATCGTCAACATCACCTCCAGCGCGGTGAAGGCGCCGATCGACATCCTTGGCCTGTCCAATGGCGCGCGCGCCGGC
CTCACCGGCTTCGTCGCCGGGCTTGCGCGCAGCACCGTGGCCGACAACGTCACCATCAACAACCTGTTGCCTGGGCAGTT
CGCCACCGACCGCCTGCGCGGCAACTTCGCCGCCATCGCGCAGCAACAGGGCAGCAGTGCCGACGAAGTCGCCGAACGCA
AGCGTGCGGGCATTCCAGCGGCGCGTTTTGGCGAGCCGGACGAGTTCGGCGCGGCTTGCGCCTTTCTGTGCAGCGCGCAG
GCCGGCTATATCACCGGACAGAATCTGTTGATCGATGGCGGCAGCTATCCCGGCACGTTCTAG

Upstream 100 bases:

>100_bases
GTCATGCAGATCAGGTGAGCGAGGCACTGCAACGCTTCGTTGCGTCCGTGCCATGAGCCGATCGTCGATCATGCGACATC
GCTGATCGAGGGACACTCGC

Downstream 100 bases:

>100_bases
CGTGGCGTCGTCGCGCACCACGCATCGATTCCCTCCGCCCTAGCCCTGGGGCGACAATAGCGGCGCCATGACCAGTACTT
TCGACCCCCGCCACGTCCGG

Product: oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDLGIAGRWALVCAASKGLGLGCARALAGEGGNVVIAARGREALEHAADALRALPGSGEVRCVVADIATPEGRSAALAAC
PQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAG
LTGFVAGLARSTVADNVTINNLLPGQFATDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
AGYITGQNLLIDGGSYPGTF

Sequences:

>Translated_260_residues
MDLGIAGRWALVCAASKGLGLGCARALAGEGGNVVIAARGREALEHAADALRALPGSGEVRCVVADIATPEGRSAALAAC
PQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAG
LTGFVAGLARSTVADNVTINNLLPGQFATDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
AGYITGQNLLIDGGSYPGTF
>Mature_260_residues
MDLGIAGRWALVCAASKGLGLGCARALAGEGGNVVIAARGREALEHAADALRALPGSGEVRCVVADIATPEGRSAALAAC
PQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIELIRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAG
LTGFVAGLARSTVADNVTINNLLPGQFATDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
AGYITGQNLLIDGGSYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=29.1828793774319, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=28.4046692607004, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=29.1828793774319, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=27.5193798449612, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=26.4591439688716, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=25.1082251082251, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI226371731, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=32.5670498084291, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=32.4427480916031, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=28.4615384615385, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=28.0632411067194, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=23.6434108527132, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789208, Length=270, Percent_Identity=27.037037037037, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=24.904214559387, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.9610894941634, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=28.2945736434109, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=28.6259541984733, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=30.9433962264151, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=30.0380228136882, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=26.7175572519084, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=26.7399267399267, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=25.9541984732824, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.1368821292776, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=26.7657992565056, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=27.3764258555133, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=25.390625, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=257, Percent_Identity=26.4591439688716, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=27.9352226720648, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=25.0950570342205, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=27.843137254902, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=29.7297297297297, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=27.3076923076923, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=27.4509803921569, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=25.3787878787879, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26752; Mature: 26752

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIAGRWALVCAASKGLGLGCARALAGEGGNVVIAARGREALEHAADALRALPGSGEV
CCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCE
RCVVADIATPEGRSAALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIEL
EEEEEECCCCCCCCCCEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
IRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVADNVTIN
HHHHHHHHHHHHHHHEEEECHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEC
NLLPGQFATDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
CCCCCCHHHHHHCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCC
AGYITGQNLLIDGGSYPGTF
CCEEECCEEEEECCCCCCCC
>Mature Secondary Structure
MDLGIAGRWALVCAASKGLGLGCARALAGEGGNVVIAARGREALEHAADALRALPGSGEV
CCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCE
RCVVADIATPEGRSAALAACPQVDILINNAGGPPPGDFRQWERADWLRALDANMLAPIEL
EEEEEECCCCCCCCCCEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
IRATVDGMRARRFGRIVNITSSAVKAPIDILGLSNGARAGLTGFVAGLARSTVADNVTIN
HHHHHHHHHHHHHHHEEEECHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCEEEC
NLLPGQFATDRLRGNFAAIAQQQGSSADEVAERKRAGIPAARFGEPDEFGAACAFLCSAQ
CCCCCCHHHHHHCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHCC
AGYITGQNLLIDGGSYPGTF
CCEEECCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]