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The map label for this gene is bplD [H]

Identifier: 21240818

GI number: 21240818

Start: 53953

End: 55071

Strand: Direct

Name: bplD [H]

Synonym: XAC0044

Alternate gene names: 21240818

Gene position: 53953-55071 (Clockwise)

Preceding gene: 21240817

Following gene: 21240834

Centisome position: 1.04

GC content: 65.86

Gene sequence:

>1119_bases
ATGCACATCACTTATGTCCTCGGTACCCGCCCGGAAATCATCAAGCTGGCATCGCTGATCGCGGCCAGTCTGCGCGATGG
ACTGAACTTTTCGATCGTCCATACCAATCAGCATTACGACGAGGCGATGGACCGGGTGTTCTTCGACGAGTTGGGTCTGC
CCCCGGCCGATTACAATCTCGGCGTGGGTTCGGCGCCGCATGGCGTGCAGATCGGACGCATGTTGTGCGGCATCGAGCCG
GTGCTTGCGACGTTGCAGCCGGATGTGGTGGTGGTGCAGGGCGACACCAACAGCGCCTTGGCAGGCGCCATGGCCGCCAG
CAAGCTGGAGATCGCCGTTGCCCATGTCGAGGCGGGCCTGCGCAGCCGCGACCGCAGCATGCCTGAAGAAGTCAATCGCG
TGCTGATCGATCACCTGTCCGACTACCTGTTCTGTCCCACCGCACTGCAGGCGCAGATCCTGCGCGATGAAGGCCTGACC
GGCGCCCGCATCCGCATCACCGGCAACACTGTCGCCGACGCGACCCTGGCGCATGCCCAGACCGCACTGCGCCGCTCGAC
CATCCTGCAACGGCTTGGCCTGCGCGAAGGCGGCTATCACTTGCTTACCTGCCATCGCCGTTCAAATACCGAAGATCCCG
CGCATTTCGCGGCGCTGATGCAGGCCGTCACCTCGATCTCCGAGGATCAGGGGTTGCCGCTGGTCTTTCCGATGCACCCG
CGCCTGGATGCGCTGGGGAGCGTGGCGGCCGCGCGGCATCGCGTGCTGCGGGCGATCGGTCCGGTCGGTTACCTGGACAT
GCTGGCGCTCCAGCAAGGCGCGGCCTTGATCATGACCGACAGTGGCGGCATCCAGGAAGAAGCCTGCATCCTGCAGCGCA
AATGCCTGGTGCTGCGTACCAACACCGAGCGGCCGGAGACCCTGCAGATCGGCGGGGCGGAACTCCCCCACGGCCTGGAC
CAGGACGCCCTGCGGAGTGCCGCCGATCGCCTGCTGGCGCGTTCGGTGGCATGGCGCAATCCCTTTGGCGATGGCCATGC
GTTTCGCTGCATCCTGGACACGCTCCTGGCGCGGGACGAACACCCCAGCGCGTCGCGTCCGCGCCTGCAGCACGCGTAG

Upstream 100 bases:

>100_bases
CAGCATTGGTCGCTTTGGCTGGATATGAGCATCATCGCGCAGACCTGCGTGATCGTGCTGTTCGACCGCGACGCCTACTG
AACTCGGATCCGGAAGTCCC

Downstream 100 bases:

>100_bases
GCGGCGCGTAGCGAAGGTCTCAGCGCGCAGGCGCGCGATGGCATGGCTGGTTCTAGACGCGACGCAGAGCCGAGCGCTGG
GACGGCCTCATGACATCCCG

Product: lipopolysaccharide biosynthesis protein

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MHITYVLGTRPEIIKLASLIAASLRDGLNFSIVHTNQHYDEAMDRVFFDELGLPPADYNLGVGSAPHGVQIGRMLCGIEP
VLATLQPDVVVVQGDTNSALAGAMAASKLEIAVAHVEAGLRSRDRSMPEEVNRVLIDHLSDYLFCPTALQAQILRDEGLT
GARIRITGNTVADATLAHAQTALRRSTILQRLGLREGGYHLLTCHRRSNTEDPAHFAALMQAVTSISEDQGLPLVFPMHP
RLDALGSVAAARHRVLRAIGPVGYLDMLALQQGAALIMTDSGGIQEEACILQRKCLVLRTNTERPETLQIGGAELPHGLD
QDALRSAADRLLARSVAWRNPFGDGHAFRCILDTLLARDEHPSASRPRLQHA

Sequences:

>Translated_372_residues
MHITYVLGTRPEIIKLASLIAASLRDGLNFSIVHTNQHYDEAMDRVFFDELGLPPADYNLGVGSAPHGVQIGRMLCGIEP
VLATLQPDVVVVQGDTNSALAGAMAASKLEIAVAHVEAGLRSRDRSMPEEVNRVLIDHLSDYLFCPTALQAQILRDEGLT
GARIRITGNTVADATLAHAQTALRRSTILQRLGLREGGYHLLTCHRRSNTEDPAHFAALMQAVTSISEDQGLPLVFPMHP
RLDALGSVAAARHRVLRAIGPVGYLDMLALQQGAALIMTDSGGIQEEACILQRKCLVLRTNTERPETLQIGGAELPHGLD
QDALRSAADRLLARSVAWRNPFGDGHAFRCILDTLLARDEHPSASRPRLQHA
>Mature_372_residues
MHITYVLGTRPEIIKLASLIAASLRDGLNFSIVHTNQHYDEAMDRVFFDELGLPPADYNLGVGSAPHGVQIGRMLCGIEP
VLATLQPDVVVVQGDTNSALAGAMAASKLEIAVAHVEAGLRSRDRSMPEEVNRVLIDHLSDYLFCPTALQAQILRDEGLT
GARIRITGNTVADATLAHAQTALRRSTILQRLGLREGGYHLLTCHRRSNTEDPAHFAALMQAVTSISEDQGLPLVFPMHP
RLDALGSVAAARHRVLRAIGPVGYLDMLALQQGAALIMTDSGGIQEEACILQRKCLVLRTNTERPETLQIGGAELPHGLD
QDALRSAADRLLARSVAWRNPFGDGHAFRCILDTLLARDEHPSASRPRLQHA

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=374, Percent_Identity=35.5614973262032, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 40365; Mature: 40365

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHITYVLGTRPEIIKLASLIAASLRDGLNFSIVHTNQHYDEAMDRVFFDELGLPPADYNL
CEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCC
GVGSAPHGVQIGRMLCGIEPVLATLQPDVVVVQGDTNSALAGAMAASKLEIAVAHVEAGL
CCCCCCCCHHHHHHHHCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RSRDRSMPEEVNRVLIDHLSDYLFCPTALQAQILRDEGLTGARIRITGNTVADATLAHAQ
HHHCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHH
TALRRSTILQRLGLREGGYHLLTCHRRSNTEDPAHFAALMQAVTSISEDQGLPLVFPMHP
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
RLDALGSVAAARHRVLRAIGPVGYLDMLALQQGAALIMTDSGGIQEEACILQRKCLVLRT
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCEEEEEE
NTERPETLQIGGAELPHGLDQDALRSAADRLLARSVAWRNPFGDGHAFRCILDTLLARDE
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
HPSASRPRLQHA
CCCCCCCCCCCC
>Mature Secondary Structure
MHITYVLGTRPEIIKLASLIAASLRDGLNFSIVHTNQHYDEAMDRVFFDELGLPPADYNL
CEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCC
GVGSAPHGVQIGRMLCGIEPVLATLQPDVVVVQGDTNSALAGAMAASKLEIAVAHVEAGL
CCCCCCCCHHHHHHHHCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RSRDRSMPEEVNRVLIDHLSDYLFCPTALQAQILRDEGLTGARIRITGNTVADATLAHAQ
HHHCCCCHHHHHHHHHHHHHHHEECCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHH
TALRRSTILQRLGLREGGYHLLTCHRRSNTEDPAHFAALMQAVTSISEDQGLPLVFPMHP
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCC
RLDALGSVAAARHRVLRAIGPVGYLDMLALQQGAALIMTDSGGIQEEACILQRKCLVLRT
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCEEEEEE
NTERPETLQIGGAELPHGLDQDALRSAADRLLARSVAWRNPFGDGHAFRCILDTLLARDE
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
HPSASRPRLQHA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]