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The map label for this gene is hyuA [H]

Identifier: 21228700

GI number: 21228700

Start: 3094328

End: 3095704

Strand: Reverse

Name: hyuA [H]

Synonym: MM_2598

Alternate gene names: 21228700

Gene position: 3095704-3094328 (Counterclockwise)

Preceding gene: 21228704

Following gene: 21228699

Centisome position: 75.57

GC content: 47.71

Gene sequence:

>1377_bases
ATGCAATACAGCATGGGCATTGACGCGGGAGGGACATACACCGATTCGATCATCATCCGGGATTCCGATGGCAAGGTGAT
GGACTCGAATAAAGCCCTTACAACTTATCCTGACCTTCTTGCAGGAATTAAAAATTCTATTGACGGGCTGGACGAGCAAT
ATTTAAAAGATGTGAAAATGGTATCGGTTTCGACAACTCTTGCTACAAACACAATCCTTGAAAAAAATGGCTATCCTGTA
GGTTTGATCCTTGTAGGGGATTACGAAGTCCCGGAAAGGATGCAGGCTGAATATTATACCGTGGTAAAAGGAGGGCACGA
CCATCATGGAGCTGAGCTTACTTCCCTTGATATGGAAGCAGTTGAGGCTTTTGTGAATAAAGTAAAAGACAGGGTATCAG
CTTTTGCAGTATCTTCATACTTCAGCATAAGGAACCCTGCCCATGAGCTGGCAATCAAAGCCCGCCTCAAGGAACTGGGA
TTTTCTGTTGTCTGCGGACACGAGCTCTCGCTTGACCTTGGAGCTTATGAAAGGGGAATTACAGCTTATCTCAACGCCCA
GCTTATCCCTATTGCAAGCCAGTTTATCCTTTCTATCAGGGAAGAGATCAGGCGCAGGGGAATGGATGCCAGGCTGCTCA
TGCTCAAATGCGACGGCTCTGTTGTGGGCATCAACGAAGCCCTGGAAAAACCAATAGAATCTATCTTTTCAGGCCCTGCT
GCAAGCCTTGTAGGCGCATCCCACCTTTCCGGGCTTGAGACCTGTGCAGTAATAGATGTGGGCGGGACCAGCACTGATGT
CTCCATGCTCGAAAATGGGCTTCCTGAGCTCTGCTCTGAAGGGGCAGTTGTGGGGGGCTGGCAGACCAAGGTCAAAGCTA
TCCGCATGGAAACCTCTGCAATGGGTGGGGACAGCCACGTCTGGGTTAAAAATATGAAAATTAACATAGGCCCCCGCAGG
GTTATTCCACTCTGCGTTGCTGCTGTCAAATATCCCGGTTTTCTTGAAATCCTTAAAAAAGGAAGAATTCCAGGAACCAT
GCACCTTGAAGAGAATATACAGCCCACAAAGTTTTTCATAAGGACAGGTCTGGAGGCTTCAAACCTTGGGAGTTATGAAA
AAGAACTTTTTGACAGGATAGGAGATACCCCAGCCTCCCTTAACGATATCTTCTGGGAAACTCAGAAAACCCTGTCTCCC
GGACTTCTCGACTCCCTTCTAAGAAAACGACTTATCCAGGCAATTGGCTTTACCCCAACTGATGCCCTTCATGTCCTCGG
GGAATACAGGGGCTGGAATACGGAAGCGTCTATTGCCGGGGCAAAGCTTCTGGAACGCTATACTCATAAGGACTATATTG
AGTCTGCAAGAGCATAA

Upstream 100 bases:

>100_bases
TTATACAGGATATTTTACGGCGTTATTTTATATCTGGCAAATTAATCGAGAAACAATTTTATGAACCCCATTCATAAAAA
AACCAAAAGGAGATACGCAA

Downstream 100 bases:

>100_bases
AAAAAGACGTTGCAAGGGACATGGCGCTGAACCTGATGTCCTTTGTCTTGAAAGATGTACCTTCACAGGAAATTGAAAAA
ATCATCGTTTCTGACAGGTT

Product: hypothetical protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MQYSMGIDAGGTYTDSIIIRDSDGKVMDSNKALTTYPDLLAGIKNSIDGLDEQYLKDVKMVSVSTTLATNTILEKNGYPV
GLILVGDYEVPERMQAEYYTVVKGGHDHHGAELTSLDMEAVEAFVNKVKDRVSAFAVSSYFSIRNPAHELAIKARLKELG
FSVVCGHELSLDLGAYERGITAYLNAQLIPIASQFILSIREEIRRRGMDARLLMLKCDGSVVGINEALEKPIESIFSGPA
ASLVGASHLSGLETCAVIDVGGTSTDVSMLENGLPELCSEGAVVGGWQTKVKAIRMETSAMGGDSHVWVKNMKINIGPRR
VIPLCVAAVKYPGFLEILKKGRIPGTMHLEENIQPTKFFIRTGLEASNLGSYEKELFDRIGDTPASLNDIFWETQKTLSP
GLLDSLLRKRLIQAIGFTPTDALHVLGEYRGWNTEASIAGAKLLERYTHKDYIESARA

Sequences:

>Translated_458_residues
MQYSMGIDAGGTYTDSIIIRDSDGKVMDSNKALTTYPDLLAGIKNSIDGLDEQYLKDVKMVSVSTTLATNTILEKNGYPV
GLILVGDYEVPERMQAEYYTVVKGGHDHHGAELTSLDMEAVEAFVNKVKDRVSAFAVSSYFSIRNPAHELAIKARLKELG
FSVVCGHELSLDLGAYERGITAYLNAQLIPIASQFILSIREEIRRRGMDARLLMLKCDGSVVGINEALEKPIESIFSGPA
ASLVGASHLSGLETCAVIDVGGTSTDVSMLENGLPELCSEGAVVGGWQTKVKAIRMETSAMGGDSHVWVKNMKINIGPRR
VIPLCVAAVKYPGFLEILKKGRIPGTMHLEENIQPTKFFIRTGLEASNLGSYEKELFDRIGDTPASLNDIFWETQKTLSP
GLLDSLLRKRLIQAIGFTPTDALHVLGEYRGWNTEASIAGAKLLERYTHKDYIESARA
>Mature_458_residues
MQYSMGIDAGGTYTDSIIIRDSDGKVMDSNKALTTYPDLLAGIKNSIDGLDEQYLKDVKMVSVSTTLATNTILEKNGYPV
GLILVGDYEVPERMQAEYYTVVKGGHDHHGAELTSLDMEAVEAFVNKVKDRVSAFAVSSYFSIRNPAHELAIKARLKELG
FSVVCGHELSLDLGAYERGITAYLNAQLIPIASQFILSIREEIRRRGMDARLLMLKCDGSVVGINEALEKPIESIFSGPA
ASLVGASHLSGLETCAVIDVGGTSTDVSMLENGLPELCSEGAVVGGWQTKVKAIRMETSAMGGDSHVWVKNMKINIGPRR
VIPLCVAAVKYPGFLEILKKGRIPGTMHLEENIQPTKFFIRTGLEASNLGSYEKELFDRIGDTPASLNDIFWETQKTLSP
GLLDSLLRKRLIQAIGFTPTDALHVLGEYRGWNTEASIAGAKLLERYTHKDYIESARA

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Drosophila melanogaster, GI45550492, Length=374, Percent_Identity=26.2032085561497, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 50026; Mature: 50026

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYSMGIDAGGTYTDSIIIRDSDGKVMDSNKALTTYPDLLAGIKNSIDGLDEQYLKDVKM
CCCCCCCCCCCCEECEEEEECCCCCEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHH
VSVSTTLATNTILEKNGYPVGLILVGDYEVPERMQAEYYTVVKGGHDHHGAELTSLDMEA
EEEEHHHHHHHHEECCCCEEEEEEEECCCCCHHHCCCEEEEEECCCCCCCCEEHHHHHHH
VEAFVNKVKDRVSAFAVSSYFSIRNPAHELAIKARLKELGFSVVCGHELSLDLGAYERGI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCEEECCHHHCCC
TAYLNAQLIPIASQFILSIREEIRRRGMDARLLMLKCDGSVVGINEALEKPIESIFSGPA
EEEECCEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCH
ASLVGASHLSGLETCAVIDVGGTSTDVSMLENGLPELCSEGAVVGGWQTKVKAIRMETSA
HHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCHHHHHCCCEECCHHHHHHEEEEEHHC
MGGDSHVWVKNMKINIGPRRVIPLCVAAVKYPGFLEILKKGRIPGTMHLEENIQPTKFFI
CCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCHHHHHH
RTGLEASNLGSYEKELFDRIGDTPASLNDIFWETQKTLSPGLLDSLLRKRLIQAIGFTPT
HCCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCH
DALHVLGEYRGWNTEASIAGAKLLERYTHKDYIESARA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYSMGIDAGGTYTDSIIIRDSDGKVMDSNKALTTYPDLLAGIKNSIDGLDEQYLKDVKM
CCCCCCCCCCCCEECEEEEECCCCCEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHH
VSVSTTLATNTILEKNGYPVGLILVGDYEVPERMQAEYYTVVKGGHDHHGAELTSLDMEA
EEEEHHHHHHHHEECCCCEEEEEEEECCCCCHHHCCCEEEEEECCCCCCCCEEHHHHHHH
VEAFVNKVKDRVSAFAVSSYFSIRNPAHELAIKARLKELGFSVVCGHELSLDLGAYERGI
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCEEECCHHHCCC
TAYLNAQLIPIASQFILSIREEIRRRGMDARLLMLKCDGSVVGINEALEKPIESIFSGPA
EEEECCEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCH
ASLVGASHLSGLETCAVIDVGGTSTDVSMLENGLPELCSEGAVVGGWQTKVKAIRMETSA
HHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCHHHHHCCCEECCHHHHHHEEEEEHHC
MGGDSHVWVKNMKINIGPRRVIPLCVAAVKYPGFLEILKKGRIPGTMHLEENIQPTKFFI
CCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCHHHHHH
RTGLEASNLGSYEKELFDRIGDTPASLNDIFWETQKTLSPGLLDSLLRKRLIQAIGFTPT
HCCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCH
DALHVLGEYRGWNTEASIAGAKLLERYTHKDYIESARA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]