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The map label for this gene is hypB [H]

Identifier: 21228265

GI number: 21228265

Start: 2566275

End: 2566961

Strand: Reverse

Name: hypB [H]

Synonym: MM_2163

Alternate gene names: 21228265

Gene position: 2566961-2566275 (Counterclockwise)

Preceding gene: 21228266

Following gene: 21228264

Centisome position: 62.66

GC content: 44.54

Gene sequence:

>687_bases
GTGATGTTTATGTTAATGCATGTAATCCATATGGGACATGATGTTTACAAGGCAAATGACAAAATTGCCGAAAAGAACAG
GAAAACTCTTGACAAACACGGTGTCTTCTCAGTAAATGTTATGGGAGCAATAGGTTCAGGAAAGACCACTTTGATTGAAG
AGGCTATCAGGCACCTTAAGGATAAATACAGAATAGCCGTTGTTGCAGGCGATGTTATTGCAGAGATGGACGCTTCCCGT
TTTAGAAAGCTGGATGTTCCGACAATCCCTGTAAATACCGGAAAAGAGTGCCACCTGGATGCGAAGCTTGTAGAAAAGGC
TCTGGGTGAGATAGACCTTGATAACACGGATCTCCTGATTATTGAGAATGTAGGCAACCTGATCTGCCCTGTGGACTTCA
AGCTGGGAGAACACCTGCGGGTTGTGATTGTGAGCGTCACGGAAGGAGACGACATTATCCTCAAGCACCCCATGATTTTC
AAGACTTCAGAGCTTGCTGTCATAAACAAGGTTGATATTGCACATGCAGTTGATGTTGATTCCGAAAAGATGAGGGACGA
CATCCTTTCCTTAAACCCTGAAGTGCCGGTGATCCTTACATCGAAACACGACTGGGAAAGCCTTGAAACATGGATAGGTT
TCATCGAGCTCGGACTCACCAGAGCAAAGGAAGCTCAGAAAAAGTAA

Upstream 100 bases:

>100_bases
TAGCCTTTAGCTTCTCAAATTTAATTCAATTTAATATAAGTTAATTCAATTTAATTTAATAATAAATATCGAATTCCGAT
CAAGATAATAAGCAACCCTG

Downstream 100 bases:

>100_bases
GGCAGATGAAAGACAAGTAAAATGAAGAGCCTGGAATAGGTCAAGCCTGGAATAAGTTAAATCAAGAATAGACCATTTAT
CTGTTCTCTTCCTTTTCTTC

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MMFMLMHVIHMGHDVYKANDKIAEKNRKTLDKHGVFSVNVMGAIGSGKTTLIEEAIRHLKDKYRIAVVAGDVIAEMDASR
FRKLDVPTIPVNTGKECHLDAKLVEKALGEIDLDNTDLLIIENVGNLICPVDFKLGEHLRVVIVSVTEGDDIILKHPMIF
KTSELAVINKVDIAHAVDVDSEKMRDDILSLNPEVPVILTSKHDWESLETWIGFIELGLTRAKEAQKK

Sequences:

>Translated_228_residues
MMFMLMHVIHMGHDVYKANDKIAEKNRKTLDKHGVFSVNVMGAIGSGKTTLIEEAIRHLKDKYRIAVVAGDVIAEMDASR
FRKLDVPTIPVNTGKECHLDAKLVEKALGEIDLDNTDLLIIENVGNLICPVDFKLGEHLRVVIVSVTEGDDIILKHPMIF
KTSELAVINKVDIAHAVDVDSEKMRDDILSLNPEVPVILTSKHDWESLETWIGFIELGLTRAKEAQKK
>Mature_228_residues
MMFMLMHVIHMGHDVYKANDKIAEKNRKTLDKHGVFSVNVMGAIGSGKTTLIEEAIRHLKDKYRIAVVAGDVIAEMDASR
FRKLDVPTIPVNTGKECHLDAKLVEKALGEIDLDNTDLLIIENVGNLICPVDFKLGEHLRVVIVSVTEGDDIILKHPMIF
KTSELAVINKVDIAHAVDVDSEKMRDDILSLNPEVPVILTSKHDWESLETWIGFIELGLTRAKEAQKK

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=203, Percent_Identity=41.3793103448276, Blast_Score=170, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 25497; Mature: 25497

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFMLMHVIHMGHDVYKANDKIAEKNRKTLDKHGVFSVNVMGAIGSGKTTLIEEAIRHLK
CHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHH
DKYRIAVVAGDVIAEMDASRFRKLDVPTIPVNTGKECHLDAKLVEKALGEIDLDNTDLLI
HHEEEEEEECHHHHHCCHHHHHCCCCCEECCCCCCCCEECHHHHHHHHCCCCCCCCCEEE
IENVGNLICPVDFKLGEHLRVVIVSVTEGDDIILKHPMIFKTSELAVINKVDIAHAVDVD
EECCCCEEEEECCCCCCCEEEEEEEEECCCCEEEECCEEEECCCEEEEEEECHHEEECCC
SEKMRDDILSLNPEVPVILTSKHDWESLETWIGFIELGLTRAKEAQKK
HHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMFMLMHVIHMGHDVYKANDKIAEKNRKTLDKHGVFSVNVMGAIGSGKTTLIEEAIRHLK
CHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHH
DKYRIAVVAGDVIAEMDASRFRKLDVPTIPVNTGKECHLDAKLVEKALGEIDLDNTDLLI
HHEEEEEEECHHHHHCCHHHHHCCCCCEECCCCCCCCEECHHHHHHHHCCCCCCCCCEEE
IENVGNLICPVDFKLGEHLRVVIVSVTEGDDIILKHPMIFKTSELAVINKVDIAHAVDVD
EECCCCEEEEECCCCCCCEEEEEEEEECCCCEEEECCEEEECCCEEEEEEECHHEEECCC
SEKMRDDILSLNPEVPVILTSKHDWESLETWIGFIELGLTRAKEAQKK
HHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]