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The map label for this gene is rpl3p [H]

Identifier: 21228226

GI number: 21228226

Start: 2538501

End: 2539514

Strand: Direct

Name: rpl3p [H]

Synonym: MM_2124

Alternate gene names: 21228226

Gene position: 2538501-2539514 (Clockwise)

Preceding gene: 21228225

Following gene: 21228227

Centisome position: 61.97

GC content: 51.38

Gene sequence:

>1014_bases
ATGGCAAGCATACACCGACCAAAACGAGGTTCCCTCGCATTCAGTCCGCGCAAGAGGGCCAAGAGCCACATTCCAAGGTT
CAGGGCCTGGCCGGAAGCTACGGGCGAGCCAAAGCTGCAGAGTTTTGCAGGCTATAAGGTGGGTATGACCCACGTGATCA
TGGTTGATGATATAAAGAACAGCCTTACCCAGGGTATGGAGATCTCCGTACCTGTAACTGTTATCGAAACTCCTGCAATA
AGGGTCGCAGCCGTCAGGGCTTATACAGAAGACAGCACCGGGGAAAAGGCAATCGCTGAGGCATGGGCAGCAGACCTTGA
TTCTGAATTAAAGCGCAGGATACCCATCCCGGCAGCAGGCAACCAGGCTGAAGGTCTTGAAAATATCGGAAAACTGATCG
AAGAAGGCAGAGTAAGCGACATAAGGGCAGTTACCTACACACTTCCAAAAAGCCTTACTGGTGTCCCTAAAAAGGTTCCT
GACATTATGGAATCCGGAATCAGTGCAAAAGACCTCGGCGCCAAATTCGAATACGCAAAATCAATTCTCGGAAACCTTGT
AAACGTTACAGACGTTTTCAAGAACGGAACCGTTGTTGATACTGCCGCAATCACCATAGGTAAAGGTACCCAGGGTCCTG
TAAAGCGCTGGGGTATTCAGCTGCAGAAAGGCAAGCACTCCAGGCAGGGAAGCCTCAGGCAGATAGGTACCCTTGGTTCT
TTCAACCCGTCTCGCGTTTCGTGGAGAGTTCCGCAGATGGGTCAGATGGGATACCACCAGAGGACCGAGTTCAACAAGCG
TATACTCAAGATCGGGTCCGACGGGGAAGAAGTAACTCCCGAAGGCGGGTTCATTAACTACGGCCTTGTCCGCGGCGATT
ATGTCCTGATAAAAGGCAGTGTTCCAGGGCCTTCCAAGAGGCTTATAAGGCTCAGAGATCCGATCAGAGCAAAGAAAGCC
GACCTTGGCGAACCCAACATCCTGTACATAAGCAGGGAATCCAAGCAGGGGTGA

Upstream 100 bases:

>100_bases
ACCTGGTAGCGTTCGGGGAATCCAGAGCATTTCTCTTTTGTCACTTTTGTTGCTCCGACCGGAGGGACTGGTTTTCAATT
GAAGTTTACGGAGTAGAAAT

Downstream 100 bases:

>100_bases
TCTAAGATGGCTACAGCAAAAACCATAGACCTTACAGGAAGAACTGTAGGGGAAATCGAACTCCCTGCAGTGTTTGACGC
AGATTATCGCCCTGACCTTA

Product: 50S ribosomal protein L3P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEATGEPKLQSFAGYKVGMTHVIMVDDIKNSLTQGMEISVPVTVIETPAI
RVAAVRAYTEDSTGEKAIAEAWAADLDSELKRRIPIPAAGNQAEGLENIGKLIEEGRVSDIRAVTYTLPKSLTGVPKKVP
DIMESGISAKDLGAKFEYAKSILGNLVNVTDVFKNGTVVDTAAITIGKGTQGPVKRWGIQLQKGKHSRQGSLRQIGTLGS
FNPSRVSWRVPQMGQMGYHQRTEFNKRILKIGSDGEEVTPEGGFINYGLVRGDYVLIKGSVPGPSKRLIRLRDPIRAKKA
DLGEPNILYISRESKQG

Sequences:

>Translated_337_residues
MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEATGEPKLQSFAGYKVGMTHVIMVDDIKNSLTQGMEISVPVTVIETPAI
RVAAVRAYTEDSTGEKAIAEAWAADLDSELKRRIPIPAAGNQAEGLENIGKLIEEGRVSDIRAVTYTLPKSLTGVPKKVP
DIMESGISAKDLGAKFEYAKSILGNLVNVTDVFKNGTVVDTAAITIGKGTQGPVKRWGIQLQKGKHSRQGSLRQIGTLGS
FNPSRVSWRVPQMGQMGYHQRTEFNKRILKIGSDGEEVTPEGGFINYGLVRGDYVLIKGSVPGPSKRLIRLRDPIRAKKA
DLGEPNILYISRESKQG
>Mature_336_residues
ASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEATGEPKLQSFAGYKVGMTHVIMVDDIKNSLTQGMEISVPVTVIETPAIR
VAAVRAYTEDSTGEKAIAEAWAADLDSELKRRIPIPAAGNQAEGLENIGKLIEEGRVSDIRAVTYTLPKSLTGVPKKVPD
IMESGISAKDLGAKFEYAKSILGNLVNVTDVFKNGTVVDTAAITIGKGTQGPVKRWGIQLQKGKHSRQGSLRQIGTLGSF
NPSRVSWRVPQMGQMGYHQRTEFNKRILKIGSDGEEVTPEGGFINYGLVRGDYVLIKGSVPGPSKRLIRLRDPIRAKKAD
LGEPNILYISRESKQG

Specific function: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit [H]

COG id: COG0087

COG function: function code J; Ribosomal protein L3

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L3P family [H]

Homologues:

Organism=Homo sapiens, GI4506649, Length=370, Percent_Identity=29.7297297297297, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI76496472, Length=355, Percent_Identity=29.8591549295775, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4826988, Length=379, Percent_Identity=29.8153034300792, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71984538, Length=367, Percent_Identity=30.7901907356948, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71984544, Length=352, Percent_Identity=29.2613636363636, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71984550, Length=220, Percent_Identity=31.8181818181818, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324637, Length=361, Percent_Identity=29.9168975069252, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI17737907, Length=372, Percent_Identity=31.1827956989247, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24645877, Length=367, Percent_Identity=30.7901907356948, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24645879, Length=367, Percent_Identity=30.7901907356948, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24645875, Length=110, Percent_Identity=37.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24645881, Length=105, Percent_Identity=36.1904761904762, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000597
- InterPro:   IPR019928
- InterPro:   IPR019926
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00297 Ribosomal_L3 [H]

EC number: NA

Molecular weight: Translated: 36822; Mature: 36691

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: PS00474 RIBOSOMAL_L3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEATGEPKLQSFAGYKVGMTHVIMVDDIKN
CCCCCCCCCCCEEECCHHHHHHCCCCHHCCCCCCCCCCHHHHCCCEECCEEEEEEEHHHH
SLTQGMEISVPVTVIETPAIRVAAVRAYTEDSTGEKAIAEAWAADLDSELKRRIPIPAAG
HHHCCCEEEEEEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
NQAEGLENIGKLIEEGRVSDIRAVTYTLPKSLTGVPKKVPDIMESGISAKDLGAKFEYAK
CHHHHHHHHHHHHHCCCCCHHEEEEEECCHHHCCCCHHHHHHHHCCCCHHHHCCHHHHHH
SILGNLVNVTDVFKNGTVVDTAAITIGKGTQGPVKRWGIQLQKGKHSRQGSLRQIGTLGS
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHCEEEECCCCCCCCCHHHHCCCCC
FNPSRVSWRVPQMGQMGYHQRTEFNKRILKIGSDGEEVTPEGGFINYGLVRGDYVLIKGS
CCCCCEEEECCCCCCCCCHHHHHHHHHHEEECCCCCEECCCCCEEEEEEEECCEEEEECC
VPGPSKRLIRLRDPIRAKKADLGEPNILYISRESKQG
CCCCHHHHEECCCCHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
ASIHRPKRGSLAFSPRKRAKSHIPRFRAWPEATGEPKLQSFAGYKVGMTHVIMVDDIKN
CCCCCCCCCCEEECCHHHHHHCCCCHHCCCCCCCCCCHHHHCCCEECCEEEEEEEHHHH
SLTQGMEISVPVTVIETPAIRVAAVRAYTEDSTGEKAIAEAWAADLDSELKRRIPIPAAG
HHHCCCEEEEEEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
NQAEGLENIGKLIEEGRVSDIRAVTYTLPKSLTGVPKKVPDIMESGISAKDLGAKFEYAK
CHHHHHHHHHHHHHCCCCCHHEEEEEECCHHHCCCCHHHHHHHHCCCCHHHHCCHHHHHH
SILGNLVNVTDVFKNGTVVDTAAITIGKGTQGPVKRWGIQLQKGKHSRQGSLRQIGTLGS
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHCEEEECCCCCCCCCHHHHCCCCC
FNPSRVSWRVPQMGQMGYHQRTEFNKRILKIGSDGEEVTPEGGFINYGLVRGDYVLIKGS
CCCCCEEEECCCCCCCCCHHHHHHHHHHEEECCCCCEECCCCCEEEEEEEECCEEEEECC
VPGPSKRLIRLRDPIRAKKADLGEPNILYISRESKQG
CCCCHHHHEECCCCHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]