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The map label for this gene is lacA [H]

Identifier: 21228213

GI number: 21228213

Start: 2523160

End: 2523531

Strand: Reverse

Name: lacA [H]

Synonym: MM_2111

Alternate gene names: 21228213

Gene position: 2523531-2523160 (Counterclockwise)

Preceding gene: 21228214

Following gene: 21228212

Centisome position: 61.6

GC content: 41.13

Gene sequence:

>372_bases
ATGTATAGAAATTGCGGATATAAGATCGGAAGGCACACATATATAGCAGAAGGTTTGACAGTTGCCGAGAAATTAGAAGA
TGAAGATAACCTTATCATTGGAAGCCGTGTAGCAATAGGGCCAAATGTTACTCTGCTCACATCTTCAGATCCAAATAATT
CTCGTATAAGACCTTACGTAAAAATTCAGAGAGGCCGGATTTTAATAGAAGATGACGCGTGGCTTGGCGCTGGATCCATA
ATTATGCCTGATATTACAATTGGTACCGGAGCTGTAGTCGGAGCCGGATCAGTTGTCACGAAAAATGTAGATCCCTATCA
TATCGTTGCAGGAGTGCCTGCTAAAATAATAAAAAAGGTTGAGATGCCGTGA

Upstream 100 bases:

>100_bases
AAAGTACTTTGAGGCAGATATGAAAAATCTAAGAATATTTAAAAAAAAGATGCTGAAGTATTTTGCTAAAAATCTGCCCT
GTTGCAGCCTCCGGATATTT

Downstream 100 bases:

>100_bases
ATATACTATTTGATATCGGACACCCAAAAGACGTAAATGTCTTTAAAAACGTGATCTGGAAGCTTCAAGAGAGGGGTCAC
GAAATCAAGATAGTAGCAAG

Product: galactoside-O-acetyltransferase

Products: NA

Alternate protein names: GAT; Thiogalactoside acetyltransferase [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MYRNCGYKIGRHTYIAEGLTVAEKLEDEDNLIIGSRVAIGPNVTLLTSSDPNNSRIRPYVKIQRGRILIEDDAWLGAGSI
IMPDITIGTGAVVGAGSVVTKNVDPYHIVAGVPAKIIKKVEMP

Sequences:

>Translated_123_residues
MYRNCGYKIGRHTYIAEGLTVAEKLEDEDNLIIGSRVAIGPNVTLLTSSDPNNSRIRPYVKIQRGRILIEDDAWLGAGSI
IMPDITIGTGAVVGAGSVVTKNVDPYHIVAGVPAKIIKKVEMP
>Mature_123_residues
MYRNCGYKIGRHTYIAEGLTVAEKLEDEDNLIIGSRVAIGPNVTLLTSSDPNNSRIRPYVKIQRGRILIEDDAWLGAGSI
IMPDITIGTGAVVGAGSVVTKNVDPYHIVAGVPAKIIKKVEMP

Specific function: May assist cellular detoxification by acetylating non- metabolizable pyranosides, thereby preventing their reentry into the cell [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=113, Percent_Identity=36.283185840708, Blast_Score=76, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.18 [H]

Molecular weight: Translated: 13259; Mature: 13259

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRNCGYKIGRHTYIAEGLTVAEKLEDEDNLIIGSRVAIGPNVTLLTSSDPNNSRIRPYV
CCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEECEEEECCCEEEEECCCCCCCEECEEE
KIQRGRILIEDDAWLGAGSIIMPDITIGTGAVVGAGSVVTKNVDPYHIVAGVPAKIIKKV
EEECCEEEEECCCCCCCCCEEECCEEECCCCEEECCCEEECCCCCEEEEECCCHHHHHCC
EMP
CCC
>Mature Secondary Structure
MYRNCGYKIGRHTYIAEGLTVAEKLEDEDNLIIGSRVAIGPNVTLLTSSDPNNSRIRPYV
CCCCCCCCCCCEEEEECCCCHHHHCCCCCCEEEECEEEECCCEEEEECCCCCCCEECEEE
KIQRGRILIEDDAWLGAGSIIMPDITIGTGAVVGAGSVVTKNVDPYHIVAGVPAKIIKKV
EEECCEEEEECCCCCCCCCEEECCEEECCCCEEECCCEEECCCCCEEEEECCCHHHHHCC
EMP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3922433; 3901000; 9278503; 6444453; 11937062 [H]