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The map label for this gene is iorA [H]

Identifier: 21228195

GI number: 21228195

Start: 2498379

End: 2500181

Strand: Direct

Name: iorA [H]

Synonym: MM_2093

Alternate gene names: 21228195

Gene position: 2498379-2500181 (Clockwise)

Preceding gene: 21228194

Following gene: 21228196

Centisome position: 60.99

GC content: 50.08

Gene sequence:

>1803_bases
ATGACGATGCGTGAGTATATGCTTGGAAACGTAGCTATTGCCAGAGGGCTTCTTGAAGGAGGCGTGCAGGTCATTGCAGG
CTATCCCGGTACCCCTTCTTCGGAGATTATAGACACGCTTGCTTCCCGCGAAGACCGCGATTATCACATAGAATGGTCGG
TTAACGAAAAGGTTGCAATGGAAGTCGCAGTCGGAGCTGCCTGGACAGGCGTCAGGTCTGTCGTAACAATGAAGCACGTC
GGGTTAAATGTTGCAGCCGACCCTTTTATGACCCTTGCCTATGCAGGTACAAAAGGCGGGCTGATTGCAATTGTCGCCGA
TGACCCTTCCTGCCACTCTTCCCAGAACGAGCAGGATACAAGGCGCTATGCCCAGTTTGCCCTTGTGCCCTGTTTTGACC
CTTCAACCCCCCAGGAAGCCAAAGATATGCTTCCCTATGCTTTTGAGTTTTCGGAAAAGTTCGAAATCCCTGTTATTTTC
AGGCCCACTACCCGGATCTCACATGGAAAGTCGGATATCGAGCTGGGAGAAATCCCTGCAGAAAAGGCGGTTCCACACTT
TGAAAAACTGCTTGACCGCTGGGTAATGCTTCCCAAGAATGCCCGCCCCCGCCACACTCATATCCTTTCTATCCAGCAGG
CAATGGAAGACGAACTTGCAGAGTCTCCCTGGAATTCCCTTGAAATTAAACCTGGGGCAAAGATGGGAGTAATAGGTTCA
GGAATCGCATCCGTTTATGCAAAAGAAGCCCTTCAGGAACTCGGGCTTGAAGCTTCTTTCCTGAAAATAGGGACCTATCC
TGTCCCCAAAAAGCTTATCCTGGAACTGCTAAGCACAGTTGACACGGTCCTCATTTTTGAAGAGCTCGAACCGGTTGTTG
AAGAACAGGTAAGAATACTTGCCCAGGAAGCCGGACTGGAGGTTTCCGTTCTCGGAAAAGAAGGAGGTTTTGTTTCGCGG
GAAGGGGAACTGGATGTTAGCGCCTTCCTTGAAGCCCTCAGGAAAGCTTTTGACCTGGATATAGAGCCCGACTCCGGAAA
AGTCCCCCTTGAACTTGCCCCGCGTCCGCCTTCTCTCTGTGCAGGGTGTTCCCACAGGGCGACCTTTTATTCCATGAAAA
AAGTTTTCGGAAAGGACGCTATTTACCCGAGTGACATTGGCTGCTATACTCTTGGGATCCAGAGCGGGACAGTTGAGACC
ACGCTCTGCATGGGTTCAAGCATAAGCATTGCATCGGGGCTTTATCATGCAGGGGAAAAGCGCCCCATCTGCTGTTCTAT
AGGGGACTCGACTTTTTTCCATACAGGCATGAATTCTCTCCTGAATGCGGTCTTCAATAAAGCCAATATTACGGTCACCA
TCCTTGATAACCGCATAACTGCAATGACAGGCCATCAGCCAAATCCGGGAGTCGGCTTTACGGTCACAGGAGAGCCTACA
GTCGAGGTTTCACTTGCCGAACTCTGCAAAGCAATGGGTGCAGGGTTTGTAACTGTAGTTGACCCTTACAATCTTGAAGA
GACCCAGGAAGCTTTCAAAGCCGCAAAGGAATTTGAAGGGACAGCCGTGGTCATTGCAAAACAGCCCTGCGTAATCTCCG
GAAAAAGGGCAGGGATCAAAAGAGTCCCTTATATCGTTGACCCTGAAAAGTGTGAAGGCTGCAAGCAGTGTGTTAAATTC
GGCTGCCCGGCAATTGAGTTTGACGAAGAAAATAAGTGTGCTGTAATCACTTCCCTGTGCAGCGGGTGTGGAGTCTGTGC
GCAGATATGCAAATTTGATGCTATCCGGGAGGTGAAGAGATGA

Upstream 100 bases:

>100_bases
CTTCAAATTTATTGATTCGGATTGATATATAATTATTTTCAAACTGATATTTAATTTAATTAGTTGTGTTTTTCTCATCT
AAACACTGGAGACAGTTATT

Downstream 100 bases:

>100_bases
GCGAAAGAGCAGGAGAGAAGAAACTCGACCTCCTTATCACAGGGGTCGGCGGTCAGGGAGCAATCCTTGCCTCGGATATC
ATTGGAAAAGCTGCAGTCAT

Product: indolepyruvate oxidoreductase subunit

Products: NA

Alternate protein names: IOR; Indolepyruvate ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MTMREYMLGNVAIARGLLEGGVQVIAGYPGTPSSEIIDTLASREDRDYHIEWSVNEKVAMEVAVGAAWTGVRSVVTMKHV
GLNVAADPFMTLAYAGTKGGLIAIVADDPSCHSSQNEQDTRRYAQFALVPCFDPSTPQEAKDMLPYAFEFSEKFEIPVIF
RPTTRISHGKSDIELGEIPAEKAVPHFEKLLDRWVMLPKNARPRHTHILSIQQAMEDELAESPWNSLEIKPGAKMGVIGS
GIASVYAKEALQELGLEASFLKIGTYPVPKKLILELLSTVDTVLIFEELEPVVEEQVRILAQEAGLEVSVLGKEGGFVSR
EGELDVSAFLEALRKAFDLDIEPDSGKVPLELAPRPPSLCAGCSHRATFYSMKKVFGKDAIYPSDIGCYTLGIQSGTVET
TLCMGSSISIASGLYHAGEKRPICCSIGDSTFFHTGMNSLLNAVFNKANITVTILDNRITAMTGHQPNPGVGFTVTGEPT
VEVSLAELCKAMGAGFVTVVDPYNLEETQEAFKAAKEFEGTAVVIAKQPCVISGKRAGIKRVPYIVDPEKCEGCKQCVKF
GCPAIEFDEENKCAVITSLCSGCGVCAQICKFDAIREVKR

Sequences:

>Translated_600_residues
MTMREYMLGNVAIARGLLEGGVQVIAGYPGTPSSEIIDTLASREDRDYHIEWSVNEKVAMEVAVGAAWTGVRSVVTMKHV
GLNVAADPFMTLAYAGTKGGLIAIVADDPSCHSSQNEQDTRRYAQFALVPCFDPSTPQEAKDMLPYAFEFSEKFEIPVIF
RPTTRISHGKSDIELGEIPAEKAVPHFEKLLDRWVMLPKNARPRHTHILSIQQAMEDELAESPWNSLEIKPGAKMGVIGS
GIASVYAKEALQELGLEASFLKIGTYPVPKKLILELLSTVDTVLIFEELEPVVEEQVRILAQEAGLEVSVLGKEGGFVSR
EGELDVSAFLEALRKAFDLDIEPDSGKVPLELAPRPPSLCAGCSHRATFYSMKKVFGKDAIYPSDIGCYTLGIQSGTVET
TLCMGSSISIASGLYHAGEKRPICCSIGDSTFFHTGMNSLLNAVFNKANITVTILDNRITAMTGHQPNPGVGFTVTGEPT
VEVSLAELCKAMGAGFVTVVDPYNLEETQEAFKAAKEFEGTAVVIAKQPCVISGKRAGIKRVPYIVDPEKCEGCKQCVKF
GCPAIEFDEENKCAVITSLCSGCGVCAQICKFDAIREVKR
>Mature_599_residues
TMREYMLGNVAIARGLLEGGVQVIAGYPGTPSSEIIDTLASREDRDYHIEWSVNEKVAMEVAVGAAWTGVRSVVTMKHVG
LNVAADPFMTLAYAGTKGGLIAIVADDPSCHSSQNEQDTRRYAQFALVPCFDPSTPQEAKDMLPYAFEFSEKFEIPVIFR
PTTRISHGKSDIELGEIPAEKAVPHFEKLLDRWVMLPKNARPRHTHILSIQQAMEDELAESPWNSLEIKPGAKMGVIGSG
IASVYAKEALQELGLEASFLKIGTYPVPKKLILELLSTVDTVLIFEELEPVVEEQVRILAQEAGLEVSVLGKEGGFVSRE
GELDVSAFLEALRKAFDLDIEPDSGKVPLELAPRPPSLCAGCSHRATFYSMKKVFGKDAIYPSDIGCYTLGIQSGTVETT
LCMGSSISIASGLYHAGEKRPICCSIGDSTFFHTGMNSLLNAVFNKANITVTILDNRITAMTGHQPNPGVGFTVTGEPTV
EVSLAELCKAMGAGFVTVVDPYNLEETQEAFKAAKEFEGTAVVIAKQPCVISGKRAGIKRVPYIVDPEKCEGCKQCVKFG
CPAIEFDEENKCAVITSLCSGCGVCAQICKFDAIREVKR

Specific function: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates [H]

COG id: COG4231

COG function: function code C; Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017721
- InterPro:   IPR002880
- InterPro:   IPR011766
- InterPro:   IPR009014 [H]

Pfam domain/function: PF00037 Fer4; PF01855 POR_N; PF02775 TPP_enzyme_C [H]

EC number: =1.2.7.8 [H]

Molecular weight: Translated: 65037; Mature: 64906

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMREYMLGNVAIARGLLEGGVQVIAGYPGTPSSEIIDTLASREDRDYHIEWSVNEKVAM
CCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEE
EVAVGAAWTGVRSVVTMKHVGLNVAADPFMTLAYAGTKGGLIAIVADDPSCHSSQNEQDT
EEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHH
RRYAQFALVPCFDPSTPQEAKDMLPYAFEFSEKFEIPVIFRPTTRISHGKSDIELGEIPA
HHHHHEEEEECCCCCCCHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCCCCCEECCCCH
EKAVPHFEKLLDRWVMLPKNARPRHTHILSIQQAMEDELAESPWNSLEIKPGAKMGVIGS
HHCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHH
GIASVYAKEALQELGLEASFLKIGTYPVPKKLILELLSTVDTVLIFEELEPVVEEQVRIL
HHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQEAGLEVSVLGKEGGFVSREGELDVSAFLEALRKAFDLDIEPDSGKVPLELAPRPPSLC
HHHCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHH
AGCSHRATFYSMKKVFGKDAIYPSDIGCYTLGIQSGTVETTLCMGSSISIASGLYHAGEK
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHCCCC
RPICCSIGDSTFFHTGMNSLLNAVFNKANITVTILDNRITAMTGHQPNPGVGFTVTGEPT
CCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCEEECCCCC
VEVSLAELCKAMGAGFVTVVDPYNLEETQEAFKAAKEFEGTAVVIAKQPCVISGKRAGIK
EEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCC
RVPYIVDPEKCEGCKQCVKFGCPAIEFDEENKCAVITSLCSGCGVCAQICKFDAIREVKR
CCCEEECCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMREYMLGNVAIARGLLEGGVQVIAGYPGTPSSEIIDTLASREDRDYHIEWSVNEKVAM
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEE
EVAVGAAWTGVRSVVTMKHVGLNVAADPFMTLAYAGTKGGLIAIVADDPSCHSSQNEQDT
EEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCHHHH
RRYAQFALVPCFDPSTPQEAKDMLPYAFEFSEKFEIPVIFRPTTRISHGKSDIELGEIPA
HHHHHEEEEECCCCCCCHHHHHCCCEEEECCCCCCCEEEECCCCCCCCCCCCCEECCCCH
EKAVPHFEKLLDRWVMLPKNARPRHTHILSIQQAMEDELAESPWNSLEIKPGAKMGVIGS
HHCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHH
GIASVYAKEALQELGLEASFLKIGTYPVPKKLILELLSTVDTVLIFEELEPVVEEQVRIL
HHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQEAGLEVSVLGKEGGFVSREGELDVSAFLEALRKAFDLDIEPDSGKVPLELAPRPPSLC
HHHCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCHHH
AGCSHRATFYSMKKVFGKDAIYPSDIGCYTLGIQSGTVETTLCMGSSISIASGLYHAGEK
CCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHCCCC
RPICCSIGDSTFFHTGMNSLLNAVFNKANITVTILDNRITAMTGHQPNPGVGFTVTGEPT
CCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCEEECCCCC
VEVSLAELCKAMGAGFVTVVDPYNLEETQEAFKAAKEFEGTAVVIAKQPCVISGKRAGIK
EEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCC
RVPYIVDPEKCEGCKQCVKFGCPAIEFDEENKCAVITSLCSGCGVCAQICKFDAIREVKR
CCCEEECCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]