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The map label for this gene is ubiE [H]

Identifier: 21228051

GI number: 21228051

Start: 2318101

End: 2318901

Strand: Reverse

Name: ubiE [H]

Synonym: MM_1949

Alternate gene names: 21228051

Gene position: 2318901-2318101 (Counterclockwise)

Preceding gene: 21228053

Following gene: 21228049

Centisome position: 56.61

GC content: 45.07

Gene sequence:

>801_bases
ATGACCGAGTATGTGCATGGTTATTCGGAAAGAGAGGCTCTCCGCCTTTCAGAACAGGCTGAAACACTTGAAAAACTTCT
CCACCATGACACCGTATATCCACCCGGAGCAAAAGTGCTCGAAGCCGGCTGCGGAATAGGAGCCCAGACTGTAATCCTGG
CAAAAAACAACCCTGATGCGGAAATTACTTCGATTGACATTTCCCCGGAATCCCTTGAAAAAGCCAGGGAAAATACTGAA
AAAAATGGGATTAAAAATGTTAAATTCCTGCAGGCAAATATTTTTTCTCTTCCTTTTGAGGACAGCAGTTTTGACCACAT
TTTTGTCTGTTTCGTGCTTGAGCACCTGCAAAGCCCTGAAGAAGCCTTAAAAAGCCTGAAGAAAGTCCTCAAGCCCGGAG
GCACGATTACAGTAATCGAAGGAGACCATGGGTCCTGCTACTTCCATCCTGAAGGAAAAAAAGCCATTGAAGCCTGGAAC
TGTCTCATCCGGGTTCAGGCTTACATGAAAGGAAACTCCCTGGTCGGCCGCCAGATTTACCCCCTTCTACAGGAGTCCGG
GTTTGAAAAAATAAGAGTGGAGCCACGAATGGTCTATATAGATTCCAGCAAACCCGAACTTGTGGACGGCTTCATCCTGA
AAACCATCATCCCTATGGTAGAAGGCGTAAAAGAACAGTCCCTGAAAATGCAGATAATTAAAGAAGAAGAATGGGAAAAA
GGAATAGAAGAACTCCATAAGACTGCAGAACACGGAGGAACCTTCTGCTATACTTTCTTTAAAGGATGGGGGACAAAATG
A

Upstream 100 bases:

>100_bases
CGCATCTCAAGGACAGCTGTGGAAAAACTCATTAAAAACAGAAGATGCTGACCAGTGCAAGTTAATATAAATTTAATTCA
GAAAAAGGGGATCATAAGAC

Downstream 100 bases:

>100_bases
GAACCTAACTTGAGATGGATATCTATCTTAAAAATTCAAAGAGAAAGATGGGCCTGTTTTCAGGACACATTCTTCCAGAA
TACTTGCAAAAACCGATTCT

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTEYVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTE
KNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWN
CLIRVQAYMKGNSLVGRQIYPLLQESGFEKIRVEPRMVYIDSSKPELVDGFILKTIIPMVEGVKEQSLKMQIIKEEEWEK
GIEELHKTAEHGGTFCYTFFKGWGTK

Sequences:

>Translated_266_residues
MTEYVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTE
KNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWN
CLIRVQAYMKGNSLVGRQIYPLLQESGFEKIRVEPRMVYIDSSKPELVDGFILKTIIPMVEGVKEQSLKMQIIKEEEWEK
GIEELHKTAEHGGTFCYTFFKGWGTK
>Mature_265_residues
TEYVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKARENTEK
NGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNC
LIRVQAYMKGNSLVGRQIYPLLQESGFEKIRVEPRMVYIDSSKPELVDGFILKTIIPMVEGVKEQSLKMQIIKEEEWEKG
IEELHKTAEHGGTFCYTFFKGWGTK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=107, Percent_Identity=35.5140186915888, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29974; Mature: 29842

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEECCCCCC
EITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPE
EEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEHHEECCCCCCCCCHHHHHHHHHHHCCHH
EALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYMKGNSLVGRQIY
HHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
PLLQESGFEKIRVEPRMVYIDSSKPELVDGFILKTIIPMVEGVKEQSLKMQIIKEEEWEK
HHHHHCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
GIEELHKTAEHGGTFCYTFFKGWGTK
HHHHHHHHHHHCCCEEEEEECCCCCC
>Mature Secondary Structure 
TEYVHGYSEREALRLSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEECCCCCC
EITSIDISPESLEKARENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPE
EEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEHHEECCCCCCCCCHHHHHHHHHHHCCHH
EALKSLKKVLKPGGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYMKGNSLVGRQIY
HHHHHHHHHHCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHH
PLLQESGFEKIRVEPRMVYIDSSKPELVDGFILKTIIPMVEGVKEQSLKMQIIKEEEWEK
HHHHHCCCCEEEECCEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
GIEELHKTAEHGGTFCYTFFKGWGTK
HHHHHHHHHHHCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA