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The map label for this gene is wcaL [C]

Identifier: 21228048

GI number: 21228048

Start: 2314016

End: 2315143

Strand: Reverse

Name: wcaL [C]

Synonym: MM_1946

Alternate gene names: 21228048

Gene position: 2315143-2314016 (Counterclockwise)

Preceding gene: 21228049

Following gene: 21228047

Centisome position: 56.52

GC content: 44.41

Gene sequence:

>1128_bases
ATGCATTCTCTTGCAAAAACCCTGATCCAGGAAGGACATGAAGTCCATATTATTACAAGGAGCTATCCCGGCATCCCTCA
GTACAGCATGAGGGACAGAATTAAGATAATAAGGGTAGGAAGTGATCCCTTTCCGGGACAGAAGCGTTTCATGATGCCCG
GGGCATATAAAGAACTCTACAACCTTCTGAGATCGGAAAATTATGATATGATTCACTCTCACGGGCTTGACTCACCGCTA
AGCATGGCTGCTCTGCTCATGTCCAGAAAAATCGGGCTTCCTTCCGTAGTTACAAACCATTCCCTTGTAGGACACACAGC
TCTCAGCCCTGCTCTCTACCTTGCCGGCAAACTGCTTGTCAGGAATGCGGATGCCGTAATTGCAGTTAGTTCTGCAGTTG
AGAAGGATTCAAAACTGATGACAAAAAAGCCAGTTTACAGGATATTTAATGGGATCGAATGTGAAGAAAACAGCTGTAAA
GCTACCCTTCCCATCAACAGGGAAGAAAAAATCGTGATCGCCAGTGTAGCCCGAATGACAAGAAAAAAAGGAGTCCATCA
CCTTGTAAAGCTTGCCCCTGCCCTGCTTAAAAAACACGAAAACCTGATGTTTGTTATGATAGGAGACGGACCCCTTACAA
AAAAGCTGGAAAAGAGAGTAAAAAAGTGCGGCTTATCCGATAATTTCTATTTTACAGGGGAAATAACCCGGAATAAAGTG
CTTGATTATCTTGAGCAGGCTGACATCTTTGCTCACCCATCCGGAGACGAAGGGTTCGGGATTTCAATACTGGAAGCAAT
TTTGAAAAAAGTCCCTGTTGTGGCAATGAACCACAGCGGTGTTTCGGATATTATTGAGCACGGTGTAGACGGTTTTCTTG
CAGAAGACCTCACGGAATTTTCATCCTGCCTTGAAACCCTTATTGAGAACCCGGAACTGAGAACTGAATTTGCCCGGAAA
GCAGCTGAAGGGCTTCCAAAATATGACTGGGACAGGATTTATGAGCAGACATGCCGGGTGTATACAGGCATTATTAATGG
AAAACATCACAACAGGAGTCTTGAACAGGAGAGCCTATCAGAGAGCGACTACAAAAAGTTGCTTAAAAAGACAGACCAGA
GAGAATAA

Upstream 100 bases:

>100_bases
TGTATCTGTTTTATTATGGGGGGTTTAAGATCTGGAAAGATACAAAATCGCATTAATCAGTGACTGGTATTTCCCAAAAA
TAGGGGGAATCGAGTATTGT

Downstream 100 bases:

>100_bases
CTGGATAAATAAACGGAAAAATGCTGGGAAATGATGAAGAAACCGGGAAGATGAATGGTTTCAAAAGTTTTTGAACCAAT
GTTTAAATATAAAAAATATC

Product: glycosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MHSLAKTLIQEGHEVHIITRSYPGIPQYSMRDRIKIIRVGSDPFPGQKRFMMPGAYKELYNLLRSENYDMIHSHGLDSPL
SMAALLMSRKIGLPSVVTNHSLVGHTALSPALYLAGKLLVRNADAVIAVSSAVEKDSKLMTKKPVYRIFNGIECEENSCK
ATLPINREEKIVIASVARMTRKKGVHHLVKLAPALLKKHENLMFVMIGDGPLTKKLEKRVKKCGLSDNFYFTGEITRNKV
LDYLEQADIFAHPSGDEGFGISILEAILKKVPVVAMNHSGVSDIIEHGVDGFLAEDLTEFSSCLETLIENPELRTEFARK
AAEGLPKYDWDRIYEQTCRVYTGIINGKHHNRSLEQESLSESDYKKLLKKTDQRE

Sequences:

>Translated_375_residues
MHSLAKTLIQEGHEVHIITRSYPGIPQYSMRDRIKIIRVGSDPFPGQKRFMMPGAYKELYNLLRSENYDMIHSHGLDSPL
SMAALLMSRKIGLPSVVTNHSLVGHTALSPALYLAGKLLVRNADAVIAVSSAVEKDSKLMTKKPVYRIFNGIECEENSCK
ATLPINREEKIVIASVARMTRKKGVHHLVKLAPALLKKHENLMFVMIGDGPLTKKLEKRVKKCGLSDNFYFTGEITRNKV
LDYLEQADIFAHPSGDEGFGISILEAILKKVPVVAMNHSGVSDIIEHGVDGFLAEDLTEFSSCLETLIENPELRTEFARK
AAEGLPKYDWDRIYEQTCRVYTGIINGKHHNRSLEQESLSESDYKKLLKKTDQRE
>Mature_375_residues
MHSLAKTLIQEGHEVHIITRSYPGIPQYSMRDRIKIIRVGSDPFPGQKRFMMPGAYKELYNLLRSENYDMIHSHGLDSPL
SMAALLMSRKIGLPSVVTNHSLVGHTALSPALYLAGKLLVRNADAVIAVSSAVEKDSKLMTKKPVYRIFNGIECEENSCK
ATLPINREEKIVIASVARMTRKKGVHHLVKLAPALLKKHENLMFVMIGDGPLTKKLEKRVKKCGLSDNFYFTGEITRNKV
LDYLEQADIFAHPSGDEGFGISILEAILKKVPVVAMNHSGVSDIIEHGVDGFLAEDLTEFSSCLETLIENPELRTEFARK
AAEGLPKYDWDRIYEQTCRVYTGIINGKHHNRSLEQESLSESDYKKLLKKTDQRE

Specific function: Slime polysaccharide colanic acid biosynthesis. [C]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=365, Percent_Identity=26.3013698630137, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1788357, Length=127, Percent_Identity=31.496062992126, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532709, Length=299, Percent_Identity=28.7625418060201, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI9755344, Length=368, Percent_Identity=25.8152173913043, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24654571, Length=300, Percent_Identity=26.3333333333333, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR013534 [H]

Pfam domain/function: PF08323 Glyco_transf_5; PF00534 Glycos_transf_1 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 42174; Mature: 42174

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLAKTLIQEGHEVHIITRSYPGIPQYSMRDRIKIIRVGSDPFPGQKRFMMPGAYKELY
CCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
NLLRSENYDMIHSHGLDSPLSMAALLMSRKIGLPSVVTNHSLVGHTALSPALYLAGKLLV
HHHHCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
RNADAVIAVSSAVEKDSKLMTKKPVYRIFNGIECEENSCKATLPINREEKIVIASVARMT
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
RKKGVHHLVKLAPALLKKHENLMFVMIGDGPLTKKLEKRVKKCGLSDNFYFTGEITRNKV
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHH
LDYLEQADIFAHPSGDEGFGISILEAILKKVPVVAMNHSGVSDIIEHGVDGFLAEDLTEF
HHHHHHCCEEECCCCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHCCCHHHHHHHHHH
SSCLETLIENPELRTEFARKAAEGLPKYDWDRIYEQTCRVYTGIINGKHHNRSLEQESLS
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCC
ESDYKKLLKKTDQRE
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MHSLAKTLIQEGHEVHIITRSYPGIPQYSMRDRIKIIRVGSDPFPGQKRFMMPGAYKELY
CCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
NLLRSENYDMIHSHGLDSPLSMAALLMSRKIGLPSVVTNHSLVGHTALSPALYLAGKLLV
HHHHCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
RNADAVIAVSSAVEKDSKLMTKKPVYRIFNGIECEENSCKATLPINREEKIVIASVARMT
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHH
RKKGVHHLVKLAPALLKKHENLMFVMIGDGPLTKKLEKRVKKCGLSDNFYFTGEITRNKV
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHH
LDYLEQADIFAHPSGDEGFGISILEAILKKVPVVAMNHSGVSDIIEHGVDGFLAEDLTEF
HHHHHHCCEEECCCCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHCCCHHHHHHHHHH
SSCLETLIENPELRTEFARKAAEGLPKYDWDRIYEQTCRVYTGIINGKHHNRSLEQESLS
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCC
ESDYKKLLKKTDQRE
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]