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The map label for this gene is ycgM [C]

Identifier: 21227849

GI number: 21227849

Start: 2088732

End: 2089466

Strand: Direct

Name: ycgM [C]

Synonym: MM_1747

Alternate gene names: 21227849

Gene position: 2088732-2089466 (Clockwise)

Preceding gene: 21227848

Following gene: 21227850

Centisome position: 50.99

GC content: 46.8

Gene sequence:

>735_bases
ATGATTGGTAGGTTCAGGTCAGGAGATACCATTTTTTATGGAGAAATTGAAGGTGGGCGTGTTTATCCCAATGGAGGGAC
CTCTGCCGGGACGTTTGAACTTTCGGAACTTCGCGTTCTGCCCCCTTCCTTCCCTTCTAAAATTGTCTGTGTCGGCCTGA
ATTATAAGGATCATGCTGAAGAGTTTTCTATGGAAATCCCTGAATCCCCTGTCCTTTTTTTAAAGCCTCCTTCTGCGGTT
ATAGGGCATGGGGACAAGATCATTTACCCTGCATCCAGTACAAGGGTGGACTTTGAAGCCGAGCTTGCAGTCGTTATCGG
AAAGCGCTGTAAAAACATTTCAGCCGAAAAAGCCGAGGATGTCATTGCAGGATATACCTGTTTTAATGACGTGACCGCAC
GTGACCTCCAGAGAAAAGACGGACAGTGGACAAGGGCAAAGAGCTTTGATACCTTTGCAGCCCTCGGGCCCTATATAGTA
TCTACGGAAGAATTTGATATCTCCGATGCAAAGATTTCCTGCAGGGTAAACGGGGAAACAAAACAGTCCTCAAGCACTTC
AAACTTAATTTTTGACATTCCCTACCTTATTGAGTTCATCACCGAAATTATGACCCTGGAAGTGGGAGACGTTATAGCTA
CAGGAACACCCTCTGGAGTTGGAGAGCTCCACAGGGGGGACACAGTGGAAGTCGAGGTCCAGGGTATAGGAACACTTAGA
AACGAGGTTGTCTGA

Upstream 100 bases:

>100_bases
GCGGGCGAAGAGTTAAAATTTAAGTTTGGATATATCCTCTTAAAAAATGAAAGAAAGCGGAGTGAAAGACCCGCAAAAAT
AGGATAAGGAAGGCGAAGAT

Downstream 100 bases:

>100_bases
TGCTGCTCGAGAATATTGCAACCGAACTTGAACTTACGGAGCGCCACCTGATCGTGCTCAAAAAGGTAATTGAAGAAGGC
CCCATAGGAATCCTTAAACT

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MIGRFRSGDTIFYGEIEGGRVYPNGGTSAGTFELSELRVLPPSFPSKIVCVGLNYKDHAEEFSMEIPESPVLFLKPPSAV
IGHGDKIIYPASSTRVDFEAELAVVIGKRCKNISAEKAEDVIAGYTCFNDVTARDLQRKDGQWTRAKSFDTFAALGPYIV
STEEFDISDAKISCRVNGETKQSSSTSNLIFDIPYLIEFITEIMTLEVGDVIATGTPSGVGELHRGDTVEVEVQGIGTLR
NEVV

Sequences:

>Translated_244_residues
MIGRFRSGDTIFYGEIEGGRVYPNGGTSAGTFELSELRVLPPSFPSKIVCVGLNYKDHAEEFSMEIPESPVLFLKPPSAV
IGHGDKIIYPASSTRVDFEAELAVVIGKRCKNISAEKAEDVIAGYTCFNDVTARDLQRKDGQWTRAKSFDTFAALGPYIV
STEEFDISDAKISCRVNGETKQSSSTSNLIFDIPYLIEFITEIMTLEVGDVIATGTPSGVGELHRGDTVEVEVQGIGTLR
NEVV
>Mature_244_residues
MIGRFRSGDTIFYGEIEGGRVYPNGGTSAGTFELSELRVLPPSFPSKIVCVGLNYKDHAEEFSMEIPESPVLFLKPPSAV
IGHGDKIIYPASSTRVDFEAELAVVIGKRCKNISAEKAEDVIAGYTCFNDVTARDLQRKDGQWTRAKSFDTFAALGPYIV
STEEFDISDAKISCRVNGETKQSSSTSNLIFDIPYLIEFITEIMTLEVGDVIATGTPSGVGELHRGDTVEVEVQGIGTLR
NEVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=221, Percent_Identity=44.3438914027149, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI156231349, Length=221, Percent_Identity=43.8914027149321, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI13654274, Length=200, Percent_Identity=40.5, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=41.4507772020725, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI66348062, Length=193, Percent_Identity=41.4507772020725, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1787428, Length=195, Percent_Identity=40, Blast_Score=139, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17557057, Length=192, Percent_Identity=43.2291666666667, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=33.9285714285714, Blast_Score=121, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28572127, Length=221, Percent_Identity=39.8190045248869, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=38.0090497737557, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571789, Length=201, Percent_Identity=37.8109452736318, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 26571; Mature: 26571

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRFRSGDTIFYGEIEGGRVYPNGGTSAGTFELSELRVLPPSFPSKIVCVGLNYKDHAE
CCCCCCCCCEEEEEEECCCEEECCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCHHHHH
EFSMEIPESPVLFLKPPSAVIGHGDKIIYPASSTRVDFEAELAVVIGKRCKNISAEKAED
HHHCCCCCCCEEEEECCCHHHCCCCEEEECCCCCEEEEHHHEEEEEHHHHCCCCHHHHHH
VIAGYTCFNDVTARDLQRKDGQWTRAKSFDTFAALGPYIVSTEEFDISDAKISCRVNGET
HHEEEHHHCCHHHHHHHHCCCCEEECCCCCHHHHHCCEEEECCCCCCCCCEEEEEECCCC
KQSSSTSNLIFDIPYLIEFITEIMTLEVGDVIATGTPSGVGELHRGDTVEVEVQGIGTLR
CCCCCCCCEEEEHHHHHHHHHHHHHEECCCEEECCCCCCCCCCCCCCEEEEEEEECCCHH
NEVV
HCCC
>Mature Secondary Structure
MIGRFRSGDTIFYGEIEGGRVYPNGGTSAGTFELSELRVLPPSFPSKIVCVGLNYKDHAE
CCCCCCCCCEEEEEEECCCEEECCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCHHHHH
EFSMEIPESPVLFLKPPSAVIGHGDKIIYPASSTRVDFEAELAVVIGKRCKNISAEKAED
HHHCCCCCCCEEEEECCCHHHCCCCEEEECCCCCEEEEHHHEEEEEHHHHCCCCHHHHHH
VIAGYTCFNDVTARDLQRKDGQWTRAKSFDTFAALGPYIVSTEEFDISDAKISCRVNGET
HHEEEHHHCCHHHHHHHHCCCCEEECCCCCHHHHHCCEEEECCCCCCCCCEEEEEECCCC
KQSSSTSNLIFDIPYLIEFITEIMTLEVGDVIATGTPSGVGELHRGDTVEVEVQGIGTLR
CCCCCCCCEEEEHHHHHHHHHHHHHEECCCEEECCCCCCCCCCCCCCEEEEEEEECCCHH
NEVV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]