Click here to switch to the map view.

The map label for this gene is cysW [H]

Identifier: 21227664

GI number: 21227664

Start: 1861506

End: 1862195

Strand: Direct

Name: cysW [H]

Synonym: MM_1562

Alternate gene names: 21227664

Gene position: 1861506-1862195 (Clockwise)

Preceding gene: 21227663

Following gene: 21227665

Centisome position: 45.44

GC content: 38.7

Gene sequence:

>690_bases
TTGAATGAAATTATTCTGGCAATTTTTCAGGCAATAGAACTGATAGTAGAACTTGATCCAAAACTGATTCAAATAACGAA
ATTAAGCCTTTATATTTCGTTAACTGCAACACTGATAGGCTCATTAATATCGATTCCCATTGGTGGAATGATCTACTATT
ATGAATTTTGGGGAAAACGGACAATAATAAACCTGATCCAGACCCTTTACAGTGTTCCCACAGTTCTGGTGGGGCTTTTC
CTTTTCCTGTTAATATCCCAGCAGGGTCCCTTCGGGTTTTTAAAACTCCTTTTTACTCCCACTGGAATGATTATAGGGCA
GGTATTGCTAATACTGCCTCTTCTCATCGGGTTTACTATCACCGCCCTTGTTGGGGTCAGCACTCAAATAAAAGAACTGG
CAATATCCCTTGGAGCCAGCACATACCAAACAATAATTACCATTATAAAAGAAGCCCGTTATGCTATAATGAGTGCTGTG
ATACTTGGTTTTGGAAGGGCTATATCAGAAGTAGGAGTCGCCATACTTATTGGAGGCAATATCAGAGGTTTTACGAGAAC
TTTTACCACAGCCATATCTCTTGAAACATCCAGAGGTAATCTGGTGCTTTCTATAGCATTGGGGTTTATACTTCTTTCTC
TGTCTCTAATAATCAATTTCTTATTGAACTATTTGCAGGGCAAGGATTAA

Upstream 100 bases:

>100_bases
GGATGGTTAACCTGCAATTTTTTTAGCCAGAGCAACTCAAAGAAACTGAGATAACTATAATATCACTAAATTACAGTGTG
TATCAAGTTCAGGTGGTCGT

Downstream 100 bases:

>100_bases
TTCAAAAAAACTTAGTTCAGGTTTAACGATGCACATAGTGGAATTGGAAGAAATTTACAAAAATTACGGAAAACTTGAGG
TTCTGAAGAATATTAACCTG

Product: tungsten transporter, permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNEIILAIFQAIELIVELDPKLIQITKLSLYISLTATLIGSLISIPIGGMIYYYEFWGKRTIINLIQTLYSVPTVLVGLF
LFLLISQQGPFGFLKLLFTPTGMIIGQVLLILPLLIGFTITALVGVSTQIKELAISLGASTYQTIITIIKEARYAIMSAV
ILGFGRAISEVGVAILIGGNIRGFTRTFTTAISLETSRGNLVLSIALGFILLSLSLIINFLLNYLQGKD

Sequences:

>Translated_229_residues
MNEIILAIFQAIELIVELDPKLIQITKLSLYISLTATLIGSLISIPIGGMIYYYEFWGKRTIINLIQTLYSVPTVLVGLF
LFLLISQQGPFGFLKLLFTPTGMIIGQVLLILPLLIGFTITALVGVSTQIKELAISLGASTYQTIITIIKEARYAIMSAV
ILGFGRAISEVGVAILIGGNIRGFTRTFTTAISLETSRGNLVLSIALGFILLSLSLIINFLLNYLQGKD
>Mature_229_residues
MNEIILAIFQAIELIVELDPKLIQITKLSLYISLTATLIGSLISIPIGGMIYYYEFWGKRTIINLIQTLYSVPTVLVGLF
LFLLISQQGPFGFLKLLFTPTGMIIGQVLLILPLLIGFTITALVGVSTQIKELAISLGASTYQTIITIIKEARYAIMSAV
ILGFGRAISEVGVAILIGGNIRGFTRTFTTAISLETSRGNLVLSIALGFILLSLSLIINFLLNYLQGKD

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4662

COG function: function code H; ABC-type tungstate transport system, periplasmic component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=217, Percent_Identity=26.2672811059908, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24933; Mature: 24933

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIILAIFQAIELIVELDPKLIQITKLSLYISLTATLIGSLISIPIGGMIYYYEFWGKR
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHH
TIINLIQTLYSVPTVLVGLFLFLLISQQGPFGFLKLLFTPTGMIIGQVLLILPLLIGFTI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TALVGVSTQIKELAISLGASTYQTIITIIKEARYAIMSAVILGFGRAISEVGVAILIGGN
HHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
IRGFTRTFTTAISLETSRGNLVLSIALGFILLSLSLIINFLLNYLQGKD
CCHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEIILAIFQAIELIVELDPKLIQITKLSLYISLTATLIGSLISIPIGGMIYYYEFWGKR
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHH
TIINLIQTLYSVPTVLVGLFLFLLISQQGPFGFLKLLFTPTGMIIGQVLLILPLLIGFTI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TALVGVSTQIKELAISLGASTYQTIITIIKEARYAIMSAVILGFGRAISEVGVAILIGGN
HHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
IRGFTRTFTTAISLETSRGNLVLSIALGFILLSLSLIINFLLNYLQGKD
CCHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]