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The map label for this gene is 21227625

Identifier: 21227625

GI number: 21227625

Start: 1816283

End: 1817413

Strand: Reverse

Name: 21227625

Synonym: MM_1523

Alternate gene names: NA

Gene position: 1817413-1816283 (Counterclockwise)

Preceding gene: 21227626

Following gene: 21227624

Centisome position: 44.37

GC content: 46.86

Gene sequence:

>1131_bases
GTGAATCCTAAAATGAAACCGGAAATAGAAGATCAGAGAAATGGTCGCGGTAAGTCCGAAGTTGAAGAGTCGATTTCACG
CATATATCCTTTCATAAGCAGGGTATTTGATGTATATGAAATCCAGAAATCCGGAGATATCCTTTATTTCTTTGGTACGC
CTAAAGTGGATACTGAAAATGTAATGGGAGAGCTCTGGGCTCCCCTTGAACAGCGTGGTTTTGGGGGCACCCTGAAATAC
GAACTTGGAGAGCATGTTATTATTGTTGCTCCCGTAAAAAAGTCAGAGGAAAAAATCTGGATAAACCTTGCACTTTTCAT
GGCGACGGGGTTCACAACCATGATCTGTGGAGCCTGGATGTTCGGAGTCAACCTCACAAGTGACCCCATTCAGGTCTTCC
GGGGTTTGCCGTTCACACTTGCAATACTGGCTGTACTCGGCTCACATGAAATGGCGCATTATGCAATGGCCAGATACCAT
GGAATGAAAACTTCCCTTCCGTATTTTATCCCTTTTCCGACTTTCATAGGCACAATGGGGGCGGTAATCCGTTACAAAGG
ACCTATCCCTGACAGGAAAGCTCTATTTGACGTGGGAGTTGCGGGACCTCTGGTAGGACTTTTTGTCTCTATTGCAGTCA
CCATAATAGGGTTGAACCTTGATGTCCCTGAAATCAATCCCCTGCCCGATTCCCTGATGTTTGAGATTGGTCTCCCACCC
CTTTTTGTGATGATCCAGAAAGTTGTCGGAGTTACAGGAAGTAACCTTCACCCTGTGGCTTTTGCAGGCTGGGTAGGGAT
GTTTGTGACCCTTCTGAATCTCCTGCCTGCAGGACAGCTTGACGGAGGGCACGTACTCAGGGCAATGCTTGGAAAAAAGG
CGGACCGGGTATCTTCCATGATGCCGCGTATCCTTTTCCTCATAGGTTTTTACGTAATCTACTGGCTTAAAGGAGACGGC
TTTATATGGATATTCTGGGCTCTCTTCCTCTGGGCTTTCGCAGCAGCCGGGCATCCGTCCCCTCTTCACGATAAAGTGAA
ACTGGATAGAAAGCGCATCCTTATAGGGATACTTACTTTTATACTTGGCCTGCTTTGCTTCACTCTAATCCCTTTCAAGC
CCATAACCTGA

Upstream 100 bases:

>100_bases
GCAAAAAGGGATTAAAAACATCCGAATTAAAAGATGTAAATAAAATTATAAAACCTGAAAGGCTAATTTGAAAGCTAAAA
AAACCTCAAGCCTTAAAGAC

Downstream 100 bases:

>100_bases
AAAGAGAACAAAATCTGAAGCTTGCCAGGACCTGAAAAAGAACCTGAGAGAGGAAAAAAACAACAATGGAAGTGAATTTT
CGATACAGCAAAAAGAATTC

Product: Zinc metalloprotease

Products: NA

Alternate protein names: Peptidase; Membrane-Associated Zn-Dependent Protease; M50 Family Peptidase; Zinc Metalloprotease; Metalloprotease; Membrane-Associated Metallopeptidase; Zinc Protease; M50 Family Metallopeptidase; M50B Family Peptidase; Membrane Associated Metalloprotease; S2P Family Metalloprotease; Integral Membrane Protease; Peptidase Family

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNPKMKPEIEDQRNGRGKSEVEESISRIYPFISRVFDVYEIQKSGDILYFFGTPKVDTENVMGELWAPLEQRGFGGTLKY
ELGEHVIIVAPVKKSEEKIWINLALFMATGFTTMICGAWMFGVNLTSDPIQVFRGLPFTLAILAVLGSHEMAHYAMARYH
GMKTSLPYFIPFPTFIGTMGAVIRYKGPIPDRKALFDVGVAGPLVGLFVSIAVTIIGLNLDVPEINPLPDSLMFEIGLPP
LFVMIQKVVGVTGSNLHPVAFAGWVGMFVTLLNLLPAGQLDGGHVLRAMLGKKADRVSSMMPRILFLIGFYVIYWLKGDG
FIWIFWALFLWAFAAAGHPSPLHDKVKLDRKRILIGILTFILGLLCFTLIPFKPIT

Sequences:

>Translated_376_residues
MNPKMKPEIEDQRNGRGKSEVEESISRIYPFISRVFDVYEIQKSGDILYFFGTPKVDTENVMGELWAPLEQRGFGGTLKY
ELGEHVIIVAPVKKSEEKIWINLALFMATGFTTMICGAWMFGVNLTSDPIQVFRGLPFTLAILAVLGSHEMAHYAMARYH
GMKTSLPYFIPFPTFIGTMGAVIRYKGPIPDRKALFDVGVAGPLVGLFVSIAVTIIGLNLDVPEINPLPDSLMFEIGLPP
LFVMIQKVVGVTGSNLHPVAFAGWVGMFVTLLNLLPAGQLDGGHVLRAMLGKKADRVSSMMPRILFLIGFYVIYWLKGDG
FIWIFWALFLWAFAAAGHPSPLHDKVKLDRKRILIGILTFILGLLCFTLIPFKPIT
>Mature_376_residues
MNPKMKPEIEDQRNGRGKSEVEESISRIYPFISRVFDVYEIQKSGDILYFFGTPKVDTENVMGELWAPLEQRGFGGTLKY
ELGEHVIIVAPVKKSEEKIWINLALFMATGFTTMICGAWMFGVNLTSDPIQVFRGLPFTLAILAVLGSHEMAHYAMARYH
GMKTSLPYFIPFPTFIGTMGAVIRYKGPIPDRKALFDVGVAGPLVGLFVSIAVTIIGLNLDVPEINPLPDSLMFEIGLPP
LFVMIQKVVGVTGSNLHPVAFAGWVGMFVTLLNLLPAGQLDGGHVLRAMLGKKADRVSSMMPRILFLIGFYVIYWLKGDG
FIWIFWALFLWAFAAAGHPSPLHDKVKLDRKRILIGILTFILGLLCFTLIPFKPIT

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41841; Mature: 41841

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKMKPEIEDQRNGRGKSEVEESISRIYPFISRVFDVYEIQKSGDILYFFGTPKVDTEN
CCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
VMGELWAPLEQRGFGGTLKYELGEHVIIVAPVKKSEEKIWINLALFMATGFTTMICGAWM
HHHHHHCCHHHCCCCCEEEEECCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
FGVNLTSDPIQVFRGLPFTLAILAVLGSHEMAHYAMARYHGMKTSLPYFIPFPTFIGTMG
HCCCCCCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEECHHHHHHHHH
AVIRYKGPIPDRKALFDVGVAGPLVGLFVSIAVTIIGLNLDVPEINPLPDSLMFEIGLPP
HHEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCH
LFVMIQKVVGVTGSNLHPVAFAGWVGMFVTLLNLLPAGQLDGGHVLRAMLGKKADRVSSM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
MPRILFLIGFYVIYWLKGDGFIWIFWALFLWAFAAAGHPSPLHDKVKLDRKRILIGILTF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ILGLLCFTLIPFKPIT
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNPKMKPEIEDQRNGRGKSEVEESISRIYPFISRVFDVYEIQKSGDILYFFGTPKVDTEN
CCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
VMGELWAPLEQRGFGGTLKYELGEHVIIVAPVKKSEEKIWINLALFMATGFTTMICGAWM
HHHHHHCCHHHCCCCCEEEEECCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
FGVNLTSDPIQVFRGLPFTLAILAVLGSHEMAHYAMARYHGMKTSLPYFIPFPTFIGTMG
HCCCCCCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEECHHHHHHHHH
AVIRYKGPIPDRKALFDVGVAGPLVGLFVSIAVTIIGLNLDVPEINPLPDSLMFEIGLPP
HHEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCH
LFVMIQKVVGVTGSNLHPVAFAGWVGMFVTLLNLLPAGQLDGGHVLRAMLGKKADRVSSM
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHH
MPRILFLIGFYVIYWLKGDGFIWIFWALFLWAFAAAGHPSPLHDKVKLDRKRILIGILTF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
ILGLLCFTLIPFKPIT
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA