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The map label for this gene is argD [H]

Identifier: 21227508

GI number: 21227508

Start: 1687406

End: 1688593

Strand: Reverse

Name: argD [H]

Synonym: MM_1406

Alternate gene names: 21227508

Gene position: 1688593-1687406 (Counterclockwise)

Preceding gene: 21227509

Following gene: 21227507

Centisome position: 41.22

GC content: 49.24

Gene sequence:

>1188_bases
TTGACAGATAAAATTATTAATTCCGGTAACCTTGAAGCAGGGTACGATTCCGTTATAGATAAAGATTCAAAGTATGTGAT
GCAGACTTACGGGCGCCAGCCCCTCGTTCTCTCAAAAGGCAAAGGAGCAGTTGTCCAGGATATTTACGGTAAGGAGTACA
TCGACTGTGTCGCAGGCATTGCAGTAAACAATGTTGGGCACTGCCACCCCACGGTTGTTAAAGCAATACAGGCACAGGCT
GAGAAGCTGATCCACGTTTCCAACCTGTATTATACTGAAATCCAGGCAGAATTTGCAGAAACTCTTGCCTCGATTACAGG
CATGGAATGTGTCTTTTTCTGTAACTCGGGGGCCGAAGCCGTAGAGGCTGCGATGAAACTGGCCCGTGTGGCTACAGGAA
AAAGTGCTTTTGTAGCAGCCGAACATTCCTTCCACGGAAGGACCATAGGAGCTCTCAGCGTAACTCACAAGAGCATGTAC
AGGGACCCTTTTATGCCGCCTGTAAGTTCAAAAACAAGTTTTGTCCCCTATTCTGACGCCGATGCTATCAGGAAAGCGAT
TTCCGAAGATACCGCAGCAGTGGTTCTTGAACCGATCCAGGGAGAAGGCGGAGTTAATGTCCCGGATCCCGGATATTTAA
AAGAGGTAAGGGAAATCTGTGACGAAACCGGAACCCTCCTCATCTTTGACGAGGTACAGACAGGCTTTGGAAGGACAGGC
ACCTGGTTCTGTAAAGAACAATTTGGAGTTGAACCTGACATTATGAGCATGGCAAAAGCCATAGGAGGAGGGTTCCCCAT
GGGCGCCATTGCAGCTCGCAGCGGCCTCAGTTTTGGGCGCGGGCAGCATGCTTCTACCTTCGGCGGCGGGCCTCTTGCCT
GTGCAGCAGCTCTTGCTTCGATCCAGGCGATAAAAGAGGAAAAGCTTCTGGAACGCTCAAAGGAAATGGGAGCTTATTTC
ACGAAAAAACTTTCAGGCATGGCTAGGGATGATATTGTGGAGGTCCGCGGGAAAGGGCTTATGATAGGAGTTGAGATTAA
ATATCCCTGCGGAAAGTTTGTAGATTTTGCAAGGGAACATGGTGTGCTTGTAAACTGCACCTCGGACTCGGTGCTCCGCC
TTGTCCCTCCACTTGTGATTACGAAAGAACAGATAGACTCGGTTGTTGATGTCCTTGAGCAGGCGTGA

Upstream 100 bases:

>100_bases
TTTCAGTATGAACTTTCACTATTAGTCACTGATAAATTAGTCACTGATAAATTAGCCACTGATAAATTTACAATCACAAA
TTTAAAGGAAGGGAATTCAC

Downstream 100 bases:

>100_bases
ACTGATAAAAAAAGAAATCTTTGACATTGAAGAATACGTTCCCGGAAGATCCATAGAAGAGATAGCTTCAACCTACGGGC
TTAAGCCAGAATCAATTATT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTDKIINSGNLEAGYDSVIDKDSKYVMQTYGRQPLVLSKGKGAVVQDIYGKEYIDCVAGIAVNNVGHCHPTVVKAIQAQA
EKLIHVSNLYYTEIQAEFAETLASITGMECVFFCNSGAEAVEAAMKLARVATGKSAFVAAEHSFHGRTIGALSVTHKSMY
RDPFMPPVSSKTSFVPYSDADAIRKAISEDTAAVVLEPIQGEGGVNVPDPGYLKEVREICDETGTLLIFDEVQTGFGRTG
TWFCKEQFGVEPDIMSMAKAIGGGFPMGAIAARSGLSFGRGQHASTFGGGPLACAAALASIQAIKEEKLLERSKEMGAYF
TKKLSGMARDDIVEVRGKGLMIGVEIKYPCGKFVDFAREHGVLVNCTSDSVLRLVPPLVITKEQIDSVVDVLEQA

Sequences:

>Translated_395_residues
MTDKIINSGNLEAGYDSVIDKDSKYVMQTYGRQPLVLSKGKGAVVQDIYGKEYIDCVAGIAVNNVGHCHPTVVKAIQAQA
EKLIHVSNLYYTEIQAEFAETLASITGMECVFFCNSGAEAVEAAMKLARVATGKSAFVAAEHSFHGRTIGALSVTHKSMY
RDPFMPPVSSKTSFVPYSDADAIRKAISEDTAAVVLEPIQGEGGVNVPDPGYLKEVREICDETGTLLIFDEVQTGFGRTG
TWFCKEQFGVEPDIMSMAKAIGGGFPMGAIAARSGLSFGRGQHASTFGGGPLACAAALASIQAIKEEKLLERSKEMGAYF
TKKLSGMARDDIVEVRGKGLMIGVEIKYPCGKFVDFAREHGVLVNCTSDSVLRLVPPLVITKEQIDSVVDVLEQA
>Mature_394_residues
TDKIINSGNLEAGYDSVIDKDSKYVMQTYGRQPLVLSKGKGAVVQDIYGKEYIDCVAGIAVNNVGHCHPTVVKAIQAQAE
KLIHVSNLYYTEIQAEFAETLASITGMECVFFCNSGAEAVEAAMKLARVATGKSAFVAAEHSFHGRTIGALSVTHKSMYR
DPFMPPVSSKTSFVPYSDADAIRKAISEDTAAVVLEPIQGEGGVNVPDPGYLKEVREICDETGTLLIFDEVQTGFGRTGT
WFCKEQFGVEPDIMSMAKAIGGGFPMGAIAARSGLSFGRGQHASTFGGGPLACAAALASIQAIKEEKLLERSKEMGAYFT
KKLSGMARDDIVEVRGKGLMIGVEIKYPCGKFVDFAREHGVLVNCTSDSVLRLVPPLVITKEQIDSVVDVLEQA

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=398, Percent_Identity=34.6733668341709, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI13994255, Length=444, Percent_Identity=32.8828828828829, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.4548494983278, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=28.9099526066351, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI24119277, Length=407, Percent_Identity=27.7641277641278, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=29.4573643410853, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=28.1990521327014, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI188536080, Length=419, Percent_Identity=23.3890214797136, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=419, Percent_Identity=23.3890214797136, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=419, Percent_Identity=23.3890214797136, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI145693181, Length=379, Percent_Identity=43.5356200527704, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789759, Length=375, Percent_Identity=39.7333333333333, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1788044, Length=381, Percent_Identity=37.5328083989501, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=34.0476190476191, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787560, Length=389, Percent_Identity=34.7043701799486, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=30.7692307692308, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786991, Length=417, Percent_Identity=29.7362110311751, Blast_Score=131, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25144271, Length=392, Percent_Identity=38.0102040816327, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=35.2941176470588, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI25144274, Length=264, Percent_Identity=40.1515151515151, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71992977, Length=417, Percent_Identity=28.537170263789, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17541228, Length=425, Percent_Identity=25.4117647058824, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71981843, Length=178, Percent_Identity=34.2696629213483, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71992985, Length=116, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323470, Length=408, Percent_Identity=35.7843137254902, Blast_Score=252, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6324432, Length=401, Percent_Identity=36.4089775561097, Blast_Score=237, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6324386, Length=459, Percent_Identity=25.7080610021786, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=443, Percent_Identity=25.2821670428894, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=35.5329949238579, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=34.2789598108747, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=34.9881796690307, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI21356575, Length=413, Percent_Identity=29.2978208232446, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281366494, Length=292, Percent_Identity=25.6849315068493, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667139, Length=292, Percent_Identity=25.6849315068493, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667143, Length=292, Percent_Identity=25.6849315068493, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42359; Mature: 42228

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKIINSGNLEAGYDSVIDKDSKYVMQTYGRQPLVLSKGKGAVVQDIYGKEYIDCVAGI
CCCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
AVNNVGHCHPTVVKAIQAQAEKLIHVSNLYYTEIQAEFAETLASITGMECVFFCNSGAEA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
VEAAMKLARVATGKSAFVAAEHSFHGRTIGALSVTHKSMYRDPFMPPVSSKTSFVPYSDA
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCH
DAIRKAISEDTAAVVLEPIQGEGGVNVPDPGYLKEVREICDETGTLLIFDEVQTGFGRTG
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHCCCCCCC
TWFCKEQFGVEPDIMSMAKAIGGGFPMGAIAARSGLSFGRGQHASTFGGGPLACAAALAS
EEEEHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
IQAIKEEKLLERSKEMGAYFTKKLSGMARDDIVEVRGKGLMIGVEIKYPCGKFVDFAREH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHC
GVLVNCTSDSVLRLVPPLVITKEQIDSVVDVLEQA
CEEEEECCCCHHHHCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKIINSGNLEAGYDSVIDKDSKYVMQTYGRQPLVLSKGKGAVVQDIYGKEYIDCVAGI
CCCCCCCCCCCCCHHHHHCCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
AVNNVGHCHPTVVKAIQAQAEKLIHVSNLYYTEIQAEFAETLASITGMECVFFCNSGAEA
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
VEAAMKLARVATGKSAFVAAEHSFHGRTIGALSVTHKSMYRDPFMPPVSSKTSFVPYSDA
HHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCH
DAIRKAISEDTAAVVLEPIQGEGGVNVPDPGYLKEVREICDETGTLLIFDEVQTGFGRTG
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECHHCCCCCCC
TWFCKEQFGVEPDIMSMAKAIGGGFPMGAIAARSGLSFGRGQHASTFGGGPLACAAALAS
EEEEHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
IQAIKEEKLLERSKEMGAYFTKKLSGMARDDIVEVRGKGLMIGVEIKYPCGKFVDFAREH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHC
GVLVNCTSDSVLRLVPPLVITKEQIDSVVDVLEQA
CEEEEECCCCHHHHCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]