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The map label for this gene is dnaJ [H]

Identifier: 21227483

GI number: 21227483

Start: 1660567

End: 1661283

Strand: Direct

Name: dnaJ [H]

Synonym: MM_1381

Alternate gene names: 21227483

Gene position: 1660567-1661283 (Clockwise)

Preceding gene: 21227482

Following gene: 21227488

Centisome position: 40.54

GC content: 44.91

Gene sequence:

>717_bases
GTGGACTATTATCAATTATTCGATATTCCCAGAAGCGCAGGTCTTGAGGAAATCGAAGATAAGTATCATTATTTTGCAAA
AAAATATCATCCGGATAGAGCCAGGTCTCCTGATGCCCATGAAAAATTCATAAAAATCAAAGAGGCTTACGAAACCCTCA
AAGACCCTCAAAAAAGAAAAGCATATGATATGTCCCTGCCTCCGGAAGAGAAGGTGACTGAACTCTCCTCTGCCCCTGAA
AGCCAAAGCAATAGCCAGGGGACTGACCAGAACCCGCAGGTTCCAGAAATTCCCGATCTCCCCTCAGGTTCTAAATCTCC
TTTCAGAACAACCACTATTTCCTATGTATCCTTCAAATCCGGAAGCGACCCGCTGAGTGTCGGTCAATCAACCTCATCTT
CCGAATCTGATACCGTTGACTGGTCCAAATATGTTTACTCCGGAAAGAGCCAGGACATGGAAGATGAAGGCTCCTCAGGC
AAGTCAGGCAGCAATGCCAATTGGTCAAGTGTTAAGGTCAGGTACGAAGGGCTTGTGGAAGAGGTTGATGGTACCAGACG
CAAAAAACACTCTTCAATGAGTTCTTTTTTATTGAAGACCTTTGTCTTCGCACTCGTTATGATCTGTCTTCTGGCAACCA
TTGCAGTTGTTTCTCCGGGACAACTGGAGGCTATCGGGCTGGAAAGCGTGGTGAACTTCTTCGATAAATTATTCTAA

Upstream 100 bases:

>100_bases
GGTCAATAGATCAACGGTCAATATATCAACAGACCATTGGATCAAAGGGTCAATATTGGATCAAAGGGTCAATAATAGAA
TGGTTCAGGGGAGGAAAGCA

Downstream 100 bases:

>100_bases
AAAGCCAAGAGATGTAATTCACCCTGCGCTACTACAGTACTGTTCAGCATCTTTACTCGGTTGTTTCGGGGATCTTTGAA
AGCCCTTCTTCAATTTCCTT

Product: chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MDYYQLFDIPRSAGLEEIEDKYHYFAKKYHPDRARSPDAHEKFIKIKEAYETLKDPQKRKAYDMSLPPEEKVTELSSAPE
SQSNSQGTDQNPQVPEIPDLPSGSKSPFRTTTISYVSFKSGSDPLSVGQSTSSSESDTVDWSKYVYSGKSQDMEDEGSSG
KSGSNANWSSVKVRYEGLVEEVDGTRRKKHSSMSSFLLKTFVFALVMICLLATIAVVSPGQLEAIGLESVVNFFDKLF

Sequences:

>Translated_238_residues
MDYYQLFDIPRSAGLEEIEDKYHYFAKKYHPDRARSPDAHEKFIKIKEAYETLKDPQKRKAYDMSLPPEEKVTELSSAPE
SQSNSQGTDQNPQVPEIPDLPSGSKSPFRTTTISYVSFKSGSDPLSVGQSTSSSESDTVDWSKYVYSGKSQDMEDEGSSG
KSGSNANWSSVKVRYEGLVEEVDGTRRKKHSSMSSFLLKTFVFALVMICLLATIAVVSPGQLEAIGLESVVNFFDKLF
>Mature_238_residues
MDYYQLFDIPRSAGLEEIEDKYHYFAKKYHPDRARSPDAHEKFIKIKEAYETLKDPQKRKAYDMSLPPEEKVTELSSAPE
SQSNSQGTDQNPQVPEIPDLPSGSKSPFRTTTISYVSFKSGSDPLSVGQSTSSSESDTVDWSKYVYSGKSQDMEDEGSSG
KSGSNANWSSVKVRYEGLVEEVDGTRRKKHSSMSSFLLKTFVFALVMICLLATIAVVSPGQLEAIGLESVVNFFDKLF

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI9558755, Length=61, Percent_Identity=50.8196721311475, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI205360838, Length=63, Percent_Identity=52.3809523809524, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI205360840, Length=63, Percent_Identity=52.3809523809524, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI201862587, Length=62, Percent_Identity=50, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI201862518, Length=62, Percent_Identity=50, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI56549115, Length=62, Percent_Identity=50, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5453690, Length=62, Percent_Identity=48.3870967741936, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1786197, Length=63, Percent_Identity=49.2063492063492, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=63, Percent_Identity=49.2063492063492, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18858081, Length=87, Percent_Identity=39.0804597701149, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 26560; Mature: 26560

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYYQLFDIPRSAGLEEIEDKYHYFAKKYHPDRARSPDAHEKFIKIKEAYETLKDPQKRK
CCCHHHHCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHH
AYDMSLPPEEKVTELSSAPESQSNSQGTDQNPQVPEIPDLPSGSKSPFRTTTISYVSFKS
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECC
GSDPLSVGQSTSSSESDTVDWSKYVYSGKSQDMEDEGSSGKSGSNANWSSVKVRYEGLVE
CCCCHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHEEEHHHHHHH
EVDGTRRKKHSSMSSFLLKTFVFALVMICLLATIAVVSPGQLEAIGLESVVNFFDKLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDYYQLFDIPRSAGLEEIEDKYHYFAKKYHPDRARSPDAHEKFIKIKEAYETLKDPQKRK
CCCHHHHCCCHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHH
AYDMSLPPEEKVTELSSAPESQSNSQGTDQNPQVPEIPDLPSGSKSPFRTTTISYVSFKS
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECC
GSDPLSVGQSTSSSESDTVDWSKYVYSGKSQDMEDEGSSGKSGSNANWSSVKVRYEGLVE
CCCCHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHEEEHHHHHHH
EVDGTRRKKHSSMSSFLLKTFVFALVMICLLATIAVVSPGQLEAIGLESVVNFFDKLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]