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The map label for this gene is ppk2 [H]

Identifier: 21227477

GI number: 21227477

Start: 1647406

End: 1649592

Strand: Direct

Name: ppk2 [H]

Synonym: MM_1375

Alternate gene names: 21227477

Gene position: 1647406-1649592 (Clockwise)

Preceding gene: 21227476

Following gene: 21227478

Centisome position: 40.22

GC content: 46.68

Gene sequence:

>2187_bases
ATGGAACGGAACTTCCCAATTCAGTGCGCAGATTTTGATAGATTGGTTACGGATAGTGTTGAAGGAACCCGGGTTGAAGT
ATCAGGCATGCCTGACCTGAGTGACCCGTGCTTTTATGCGGATAGGGAATACAGCTGGCTCCAGTTCAATGCCAGAGTGC
TTGAAGAGGCTCTGGATGAACGCAATCCTCTGCTTGAAAGAGTCAAATTTCTTTCTATCTTCGGGAGTAACCTTGATGAA
TTTTTTATGGTCAGAGTCTCCGGGGTTCAGAAACGTATTACGGAAGGGATAAAGGAAGACTGCATAGACGAAGTGGCCCA
GGAACAGCTTCGAGTTATCCGGGAAGAACTTTTAAGGCAGCTCCCTATCAATGATAGCTGCTGGAATGAAATACTTGAAC
CCGCCCTCAGGGAAAATGGGATTGAAGTCCTTAATTACTTTGAACTTTCCGGAGAAGATAGGGAGAAACTCAGAGATTAT
TTTGAAAGAAATATTTTTCCTCTGCTAACTCCTCTCGGGTTCGACTCAGGTCATCCTTTCCCGCACATCTCAAACCTCAG
TCTTAACCTTGCAGTACTTATTGATGACCCGGAATATGGCGAGCGTTTTGCGAGGGTCAAGATCCCTCCGATGTTCTCAA
GGCTCATTGTTGTGCCTGAAGGAAAACAGGAAAAAATAATTTCCAGTTTTGAAGAACTGAAGACGGGACGCTTTGTGTGG
CTTGAACAGCTAATTGCTGCAAATCTCGACCTTCTCTTTCCAGGCCAGCGAATCCTCGGAGCTTACCCTTTCAGGATCAC
AAGAGATGCAGATCTCGGGTTTGATGAAGACGGGGATAAAGACCTCCTTACTGCTGTAAAGCAAAGGGTAGGAAGAAATT
ACTTCGGGCCCGCTGTCCGGCTTGAAACCGATTACACTATGCCTGAGAAGGTTTCTGATATCCTCCTCAAGAATCTGGAT
CTTACACGCCCACTTATGTTCAGGTCGGCTGCGCCTCTGGGGCTTTCAAGCCTTATGAAGCTTGCCCAGATTGACCGCCC
TGAGCTTAAATACGAGCCTTTCGAGCAGAAAAAACATCCCCGAATGGCTGATAGAGAAAATATTTTTGCAGCCTTAAAAA
AGAATGATATCCTTCTCCATCACCCTTATGACAGTTTTGAATCTGTAATCGACCTGGTAGAAGAAGCCGTTGACGACCCT
GATGTCCTGGCAATTAAAATGACGCTATACAGGGTAGACGATAACTCCAGGATCATCCAGGCTCTCATGAAAGCTGCAGA
CCGTAGCAAGCAGGTTGCAGTCCTTGTTGAGCTCAAAGCCCGTTTTGACGAAGAAAACAACATTGGCTGGGCAAAAGAGC
TTGAACGTAAAGGGGTACATGTAGCCTATGGTTTCCCTGGCCGCAAAACCCATGCCAAGATGTGCCTGATAGTAAGGGCT
GAAAAAGAAGGCGGCATCAGGTATTATGTGCATATGAGCACTGGAAACTACAATGCTGTTACAGGAAAGATCTATACTGA
CTGCGGCTATCTGACAAGCGATTCCTTCATAGGAAAAGATATTTCCGACCTTTTCAATGCCCTTACAGGCTATTCAAGGA
AAGACCATTATATTAAACTCCTGGTAGCTCCCCAGACAATGAGACATCAGATTCTTGAACGTATCAGGCGCGAAATTGAT
GTGCACGAGAAGTTCGGAAACGGTCATCTGATCTTCAAGATGAATTCCCTTGTGGACTACCAGTGCATCCGTGAGCTTTA
CAGGGCTTCACGGGCCGGAGTAAAGATAGACCTTATTGTCAGGGGTATCTGCTGCCTCAGACCCGGCATCTACGGGCTGA
GCGAAAATATCAGAGTAACTTCGATAGTCGGGCGTTTTCTTGAGCACTCAAGAATATATTATTTCAGGAATGGCGGAAAA
GAGGAAATCTTCCTGGGAAGCGCCGACCTTATGCCCCGCAACCTTGACAACAGGGTCGAAGTCCTCTTCCCGGTGTCCCA
GGACTATATACCTGTCATGCGCGACATCATTCTCGGTATCCATCTGAAAGATAATGTAAAAGCCCGACTCCTGCTTCCAA
ACGGACGGACTGAAAGGATTTATCCGCAGCCCGAAGAAGAAGAGCTGGATTCCCAGGTCTGGATGCTTGAGAATAGGGGC
AGCTGGGATATTAAAACAGAACGCTGA

Upstream 100 bases:

>100_bases
TGTCAAATTATAAAACAGGCAAAAATCTTATGTCCAGATCTTCTGATATTTTTGGGGACAGGTCTGAAAAGATACAAAAC
CCAGGTCATGCGTGATAGGA

Downstream 100 bases:

>100_bases
AAAAAATTTGAGGAAATCTAAATTTTTCTTTTTTCTTCTTTTTTTCACCTGTATTCGTCTTTTTTTCCTTTTATTCTACT
ATTCTTTTTTCCTTTCTGCT

Product: polyphosphate kinase

Products: NA

Alternate protein names: ATP-polyphosphate phosphotransferase 2; Polyphosphoric acid kinase 2 [H]

Number of amino acids: Translated: 728; Mature: 728

Protein sequence:

>728_residues
MERNFPIQCADFDRLVTDSVEGTRVEVSGMPDLSDPCFYADREYSWLQFNARVLEEALDERNPLLERVKFLSIFGSNLDE
FFMVRVSGVQKRITEGIKEDCIDEVAQEQLRVIREELLRQLPINDSCWNEILEPALRENGIEVLNYFELSGEDREKLRDY
FERNIFPLLTPLGFDSGHPFPHISNLSLNLAVLIDDPEYGERFARVKIPPMFSRLIVVPEGKQEKIISSFEELKTGRFVW
LEQLIAANLDLLFPGQRILGAYPFRITRDADLGFDEDGDKDLLTAVKQRVGRNYFGPAVRLETDYTMPEKVSDILLKNLD
LTRPLMFRSAAPLGLSSLMKLAQIDRPELKYEPFEQKKHPRMADRENIFAALKKNDILLHHPYDSFESVIDLVEEAVDDP
DVLAIKMTLYRVDDNSRIIQALMKAADRSKQVAVLVELKARFDEENNIGWAKELERKGVHVAYGFPGRKTHAKMCLIVRA
EKEGGIRYYVHMSTGNYNAVTGKIYTDCGYLTSDSFIGKDISDLFNALTGYSRKDHYIKLLVAPQTMRHQILERIRREID
VHEKFGNGHLIFKMNSLVDYQCIRELYRASRAGVKIDLIVRGICCLRPGIYGLSENIRVTSIVGRFLEHSRIYYFRNGGK
EEIFLGSADLMPRNLDNRVEVLFPVSQDYIPVMRDIILGIHLKDNVKARLLLPNGRTERIYPQPEEEELDSQVWMLENRG
SWDIKTER

Sequences:

>Translated_728_residues
MERNFPIQCADFDRLVTDSVEGTRVEVSGMPDLSDPCFYADREYSWLQFNARVLEEALDERNPLLERVKFLSIFGSNLDE
FFMVRVSGVQKRITEGIKEDCIDEVAQEQLRVIREELLRQLPINDSCWNEILEPALRENGIEVLNYFELSGEDREKLRDY
FERNIFPLLTPLGFDSGHPFPHISNLSLNLAVLIDDPEYGERFARVKIPPMFSRLIVVPEGKQEKIISSFEELKTGRFVW
LEQLIAANLDLLFPGQRILGAYPFRITRDADLGFDEDGDKDLLTAVKQRVGRNYFGPAVRLETDYTMPEKVSDILLKNLD
LTRPLMFRSAAPLGLSSLMKLAQIDRPELKYEPFEQKKHPRMADRENIFAALKKNDILLHHPYDSFESVIDLVEEAVDDP
DVLAIKMTLYRVDDNSRIIQALMKAADRSKQVAVLVELKARFDEENNIGWAKELERKGVHVAYGFPGRKTHAKMCLIVRA
EKEGGIRYYVHMSTGNYNAVTGKIYTDCGYLTSDSFIGKDISDLFNALTGYSRKDHYIKLLVAPQTMRHQILERIRREID
VHEKFGNGHLIFKMNSLVDYQCIRELYRASRAGVKIDLIVRGICCLRPGIYGLSENIRVTSIVGRFLEHSRIYYFRNGGK
EEIFLGSADLMPRNLDNRVEVLFPVSQDYIPVMRDIILGIHLKDNVKARLLLPNGRTERIYPQPEEEELDSQVWMLENRG
SWDIKTER
>Mature_728_residues
MERNFPIQCADFDRLVTDSVEGTRVEVSGMPDLSDPCFYADREYSWLQFNARVLEEALDERNPLLERVKFLSIFGSNLDE
FFMVRVSGVQKRITEGIKEDCIDEVAQEQLRVIREELLRQLPINDSCWNEILEPALRENGIEVLNYFELSGEDREKLRDY
FERNIFPLLTPLGFDSGHPFPHISNLSLNLAVLIDDPEYGERFARVKIPPMFSRLIVVPEGKQEKIISSFEELKTGRFVW
LEQLIAANLDLLFPGQRILGAYPFRITRDADLGFDEDGDKDLLTAVKQRVGRNYFGPAVRLETDYTMPEKVSDILLKNLD
LTRPLMFRSAAPLGLSSLMKLAQIDRPELKYEPFEQKKHPRMADRENIFAALKKNDILLHHPYDSFESVIDLVEEAVDDP
DVLAIKMTLYRVDDNSRIIQALMKAADRSKQVAVLVELKARFDEENNIGWAKELERKGVHVAYGFPGRKTHAKMCLIVRA
EKEGGIRYYVHMSTGNYNAVTGKIYTDCGYLTSDSFIGKDISDLFNALTGYSRKDHYIKLLVAPQTMRHQILERIRREID
VHEKFGNGHLIFKMNSLVDYQCIRELYRASRAGVKIDLIVRGICCLRPGIYGLSENIRVTSIVGRFLEHSRIYYFRNGGK
EEIFLGSADLMPRNLDNRVEVLFPVSQDYIPVMRDIILGIHLKDNVKARLLLPNGRTERIYPQPEEEELDSQVWMLENRG
SWDIKTER

Specific function: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) [H]

COG id: COG0855

COG function: function code P; Polyphosphate kinase

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyphosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788847, Length=665, Percent_Identity=34.2857142857143, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003414 [H]

Pfam domain/function: PF02503 PP_kinase [H]

EC number: =2.7.4.1 [H]

Molecular weight: Translated: 84078; Mature: 84078

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNFPIQCADFDRLVTDSVEGTRVEVSGMPDLSDPCFYADREYSWLQFNARVLEEALDE
CCCCCCCEECCCHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCCEEEHHHHHHHHHHHC
RNPLLERVKFLSIFGSNLDEFFMVRVSGVQKRITEGIKEDCIDEVAQEQLRVIREELLRQ
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPINDSCWNEILEPALRENGIEVLNYFELSGEDREKLRDYFERNIFPLLTPLGFDSGHPF
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEHCCCCCCCCCCCC
PHISNLSLNLAVLIDDPEYGERFARVKIPPMFSRLIVVPEGKQEKIISSFEELKTGRFVW
CCCCCCEEEEEEEECCCCCCCCEEEEECCHHHCEEEEECCCCHHHHHHHHHHHCCCHHHH
LEQLIAANLDLLFPGQRILGAYPFRITRDADLGFDEDGDKDLLTAVKQRVGRNYFGPAVR
HHHHHHCCCCEECCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
LETDYTMPEKVSDILLKNLDLTRPLMFRSAAPLGLSSLMKLAQIDRPELKYEPFEQKKHP
EECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCC
RMADRENIFAALKKNDILLHHPYDSFESVIDLVEEAVDDPDVLAIKMTLYRVDDNSRIIQ
CCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHH
ALMKAADRSKQVAVLVELKARFDEENNIGWAKELERKGVHVAYGFPGRKTHAKMCLIVRA
HHHHHCCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCEEEEEEEE
EKEGGIRYYVHMSTGNYNAVTGKIYTDCGYLTSDSFIGKDISDLFNALTGYSRKDHYIKL
CCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
LVAPQTMRHQILERIRREIDVHEKFGNGHLIFKMNSLVDYQCIRELYRASRAGVKIDLIV
EECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEHHH
RGICCLRPGIYGLSENIRVTSIVGRFLEHSRIYYFRNGGKEEIFLGSADLMPRNLDNRVE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCCCCCCCCCEE
VLFPVSQDYIPVMRDIILGIHLKDNVKARLLLPNGRTERIYPQPEEEELDSQVWMLENRG
EEEECCCCHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCCCCHHHHCCEEEEEECCC
SWDIKTER
CCCEECCC
>Mature Secondary Structure
MERNFPIQCADFDRLVTDSVEGTRVEVSGMPDLSDPCFYADREYSWLQFNARVLEEALDE
CCCCCCCEECCCHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCCEEEHHHHHHHHHHHC
RNPLLERVKFLSIFGSNLDEFFMVRVSGVQKRITEGIKEDCIDEVAQEQLRVIREELLRQ
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPINDSCWNEILEPALRENGIEVLNYFELSGEDREKLRDYFERNIFPLLTPLGFDSGHPF
CCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCEEHCCCCCCCCCCCC
PHISNLSLNLAVLIDDPEYGERFARVKIPPMFSRLIVVPEGKQEKIISSFEELKTGRFVW
CCCCCCEEEEEEEECCCCCCCCEEEEECCHHHCEEEEECCCCHHHHHHHHHHHCCCHHHH
LEQLIAANLDLLFPGQRILGAYPFRITRDADLGFDEDGDKDLLTAVKQRVGRNYFGPAVR
HHHHHHCCCCEECCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
LETDYTMPEKVSDILLKNLDLTRPLMFRSAAPLGLSSLMKLAQIDRPELKYEPFEQKKHP
EECCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHCCC
RMADRENIFAALKKNDILLHHPYDSFESVIDLVEEAVDDPDVLAIKMTLYRVDDNSRIIQ
CCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHH
ALMKAADRSKQVAVLVELKARFDEENNIGWAKELERKGVHVAYGFPGRKTHAKMCLIVRA
HHHHHCCCCCEEEEEEEEHHHCCCCCCCCHHHHHHHCCCEEEECCCCCCCCCEEEEEEEE
EKEGGIRYYVHMSTGNYNAVTGKIYTDCGYLTSDSFIGKDISDLFNALTGYSRKDHYIKL
CCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
LVAPQTMRHQILERIRREIDVHEKFGNGHLIFKMNSLVDYQCIRELYRASRAGVKIDLIV
EECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCEEEHHH
RGICCLRPGIYGLSENIRVTSIVGRFLEHSRIYYFRNGGKEEIFLGSADLMPRNLDNRVE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCEEEECCCCCCCCCCCCCEE
VLFPVSQDYIPVMRDIILGIHLKDNVKARLLLPNGRTERIYPQPEEEELDSQVWMLENRG
EEEECCCCHHHHHHHHHHEEEECCCCEEEEECCCCCCCCCCCCCCHHHHCCEEEEEECCC
SWDIKTER
CCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]