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The map label for this gene is selB [C]

Identifier: 21227411

GI number: 21227411

Start: 1558640

End: 1559692

Strand: Direct

Name: selB [C]

Synonym: MM_1309

Alternate gene names: 21227411

Gene position: 1558640-1559692 (Clockwise)

Preceding gene: 21227410

Following gene: 21227412

Centisome position: 38.05

GC content: 45.96

Gene sequence:

>1053_bases
ATGGCAAACGTTGCAATTATAGGGACAGAAAAAAGCGGCAGGACCTCCCTTGCCGCAAACCTTGGGAAAAAAGGAACTTC
CTCTGATATAACAATGTACAATAATGATAAAGAAGGCCGTAACATGGTTTTTGTGGATGCCCATAGCTACCCGAAAACCC
TGAAATCCCTGATTACGGCACTGAATATATCTGACATTGCAGTCCTGTGCATCCCTCCTCAGGGTCTGGACGCCCACACT
GGAGAATGTATCATTGCCCTAGACCTGCTGGGCTTTAAACATGGGATCATTGCCCTGACAAGGTCGGACAGCACTCACAT
GCATGCTATTGATGAACTGAAAGCAAAGTTAAAAGTGATCACTTCAGGGACTGTACTTCAGGACTGGGAATGCATTTCCC
TCAATACAAACAAAAGTGCCAAAAACCCTTTTGAAGGCGTGGACGAACTTAAAGCCAGAATCAATGAAGTGGCAGAAAAA
ATAGAAGCCGAAAACGCAGAACTTAACAGCCTGCCTGCCAGGATCTTTATAGATCACGCTTTCAATGTCACAGGCAAGGG
ATGTGTTGTCCTGGGGGTTGTAAAGCAGGGTATATCAAAGGACAAAGACAAAACCAAAATTTTTCCGCTTGACAGGGATA
TCGAAATCCGCTCTATCCAGAGCCATGATGTGGACATCGACAGCGCTCCCGCCGGTACGAGGGTGGGTATGCGCCTGAAA
AATGTCCAGGCAAAGGACATAGAAAGAGGCTTTATCATTTCCGATAAAGAAATCGTAACTACCGATTACACTCTGGAATG
TACGGTCTCAAAATTCACAAAAAAGATAGAGCCTGCGAGCGTGCTTCACCTTTTTGTCGGGCTTCAGTCCGAACCTGTGC
GCGTTGAAAAGATTCTGGTTGACGGAAACGAGGTAGAAGAGGCAAAACCGGGTAGTACCTGTGTACTGGAACTTTCAGGA
AACAAAAAGCTTGCCTACAGCAAACAGGACCGCTTCCTGCTTGCGAACCTCGACCTGACTCAGAGATTTGCAGCTTACGG
TTTTTCAAAATAA

Upstream 100 bases:

>100_bases
ATTAACCTGCATTCAAAACACACTCACATTTCCAGATTCTGGAAATACTCTCATACATATCATTTATTTAGAAAACATTA
ATCCAGAAAGGGGACTCAAA

Downstream 100 bases:

>100_bases
TATCTTACAGAAAAAGTCCGGAGAAGGGAAAAACGTGGCTCAGGGGACAGAGAAGACTCTTTACGGGAATGTCTTTCACA
GAAATATTTGCTGGCAGCGC

Product: protein translation elongation factor 1A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MANVAIIGTEKSGRTSLAANLGKKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITALNISDIAVLCIPPQGLDAHT
GECIIALDLLGFKHGIIALTRSDSTHMHAIDELKAKLKVITSGTVLQDWECISLNTNKSAKNPFEGVDELKARINEVAEK
IEAENAELNSLPARIFIDHAFNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTRVGMRLK
NVQAKDIERGFIISDKEIVTTDYTLECTVSKFTKKIEPASVLHLFVGLQSEPVRVEKILVDGNEVEEAKPGSTCVLELSG
NKKLAYSKQDRFLLANLDLTQRFAAYGFSK

Sequences:

>Translated_350_residues
MANVAIIGTEKSGRTSLAANLGKKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITALNISDIAVLCIPPQGLDAHT
GECIIALDLLGFKHGIIALTRSDSTHMHAIDELKAKLKVITSGTVLQDWECISLNTNKSAKNPFEGVDELKARINEVAEK
IEAENAELNSLPARIFIDHAFNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTRVGMRLK
NVQAKDIERGFIISDKEIVTTDYTLECTVSKFTKKIEPASVLHLFVGLQSEPVRVEKILVDGNEVEEAKPGSTCVLELSG
NKKLAYSKQDRFLLANLDLTQRFAAYGFSK
>Mature_349_residues
ANVAIIGTEKSGRTSLAANLGKKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITALNISDIAVLCIPPQGLDAHTG
ECIIALDLLGFKHGIIALTRSDSTHMHAIDELKAKLKVITSGTVLQDWECISLNTNKSAKNPFEGVDELKARINEVAEKI
EAENAELNSLPARIFIDHAFNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTRVGMRLKN
VQAKDIERGFIISDKEIVTTDYTLECTVSKFTKKIEPASVLHLFVGLQSEPVRVEKILVDGNEVEEAKPGSTCVLELSGN
KKLAYSKQDRFLLANLDLTQRFAAYGFSK

Specific function: Translation Factor Necessary For The Incorporation Of Selenocysteine Into Proteins. It Probably Replaces Ef-Tu For The Insertion Of Selenocysteine Directed By The Uga Codon. Selb Binds GTP And GDP. [C]

COG id: COG3276

COG function: function code J; Selenocysteine-specific translation elongation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI2367247, Length=237, Percent_Identity=25.3164556962025, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922690, Length=283, Percent_Identity=22.6148409893993, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 38269; Mature: 38138

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVAIIGTEKSGRTSLAANLGKKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITA
CCCEEEEECCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHH
LNISDIAVLCIPPQGLDAHTGECIIALDLLGFKHGIIALTRSDSTHMHAIDELKAKLKVI
CCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHEEEEE
TSGTVLQDWECISLNTNKSAKNPFEGVDELKARINEVAEKIEAENAELNSLPARIFIDHA
ECCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEE
FNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTRVGMRLK
CCCCCCCEEEEEEHHHCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCEECEEEE
NVQAKDIERGFIISDKEIVTTDYTLECTVSKFTKKIEPASVLHLFVGLQSEPVRVEKILV
CCCHHHCCCCEEECCCEEEEECEEEEEEHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEEE
DGNEVEEAKPGSTCVLELSGNKKLAYSKQDRFLLANLDLTQRFAAYGFSK
CCCHHCCCCCCCEEEEEECCCCEEEECCCCCEEEECCCHHHHHHHCCCCC
>Mature Secondary Structure 
ANVAIIGTEKSGRTSLAANLGKKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITA
CCEEEEECCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHH
LNISDIAVLCIPPQGLDAHTGECIIALDLLGFKHGIIALTRSDSTHMHAIDELKAKLKVI
CCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHEEEEE
TSGTVLQDWECISLNTNKSAKNPFEGVDELKARINEVAEKIEAENAELNSLPARIFIDHA
ECCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEE
FNVTGKGCVVLGVVKQGISKDKDKTKIFPLDRDIEIRSIQSHDVDIDSAPAGTRVGMRLK
CCCCCCCEEEEEEHHHCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCEECEEEE
NVQAKDIERGFIISDKEIVTTDYTLECTVSKFTKKIEPASVLHLFVGLQSEPVRVEKILV
CCCHHHCCCCEEECCCEEEEECEEEEEEHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEEE
DGNEVEEAKPGSTCVLELSGNKKLAYSKQDRFLLANLDLTQRFAAYGFSK
CCCHHCCCCCCCEEEEEECCCCEEEECCCCCEEEECCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]