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The map label for this gene is ygbD [C]

Identifier: 21227398

GI number: 21227398

Start: 1540365

End: 1541846

Strand: Direct

Name: ygbD [C]

Synonym: MM_1296

Alternate gene names: 21227398

Gene position: 1540365-1541846 (Clockwise)

Preceding gene: 21227395

Following gene: 21227399

Centisome position: 37.6

GC content: 45.21

Gene sequence:

>1482_bases
ATGAAAAGCATGGGAAGCAATTCTGGTGCGAAAGGTACTGAAGGTGGAAGTTCTCGAACAGAAGGCGAAATTCAGGAAAA
TATTTCCGAAAATGCCTCTTCAAATTCCCGGACAGAAAAAGAGTTTGCAAAAGTGGTCATTATAGGGGGAGGAGCCTGCG
GGATGGCAACTGCAACAAAAATTCGAAGGCAGAGCGATTTTGATATAACCGTGCTTTCATGGGATTCCCATACTGCTTAC
AGTCACTGCGGAATTCCTTTTGTCCTTGGAAAGGAAATTGAAAGTTTAAAAAAACTGATTGTAAAGCCTCTCGCTTTTTT
CAGGGAAAACAAAATTAATGTGAAACTGAACGAGAAAGTAACCTCAATCGATCTGAACGGGCAGGTCGTTATTACAGGGG
AAGGAACCTATCCTTTTGACAGACTGGTTATTGCTACGGGGAGCCTGCCTTTTATACCCCGGGAAAGCAGGGCAAATATT
TTACCTTATGGAATCTTTACATTGAGAAGCCTTGCCGATGGCATGCTATTTGAAAAAGCACTGGAAACTGCCCGGACAGT
CTGCATCATAGGCGGAGGCACGATAGGAATAGAATGTGCCTCAGCTCTTACAAAACGGGGGATCAGGACTACTCTTATAA
CGCGGGGCAATGACCTGCTTACCAGGCAGTTTGATTCCGATATGTCTGCAATTGTCAGGGAACATCTTGAAAGTCTCGGG
GTTGAAGTTATCACAGGGGAATCTGTAATTTTGCCTGAAAACTTCTGGAAACAAAAAACTCTGATTCTAAGGGATAGACA
GCTTCCTGCAGACCTTGTGCTGCTGGCAACTGGTGTAAAACCCGAAACCTGGCTTTCCAGAGAAACAGGAATAACGATCG
GGAAGGCAGGAGGAATAATTGTAAATGAAATGCTTCAGGTAAAAGCAGGAGAGAAATTTCTCTCCCATGTGTATGCAGGG
GGCGAATGCGCTGAAGTTATTGACCTTATAACCGGAGAGTCAAGACTGAGCCAGCTTGGTACAACAGCAAGAAGTATGGC
AGATGTGATAGGAAACAATATAACAGGCAAACATTCGACTTTCGGGCCTCTTGCTGACCCCTGGGTGGCAGTTGCCGGAG
ACCTTCAGTTCGGAGGAGTTGGGCTAACATCCGGTCAGGCTGAAAAACAGGGGATAAAGACTGTAACAGGCTTTTCCAGA
GGGCGCACCAGAGCTTCTTACTATCCCGGTCGAAAAGACCTCTATATAAAGCTTCTTTTTAAAAACAACTGTCTTGCAGG
AGCACAGCTTGCAGGAGGAGAAGGAATAAAAGAAAGGATTGACGCTCTTTCCCTGGCGATAAGAAAGGAAGCAACAATTA
AAGACCTCCTCAACCTTGAAACCTGTTATGCTCCTCCGGTTTCCACGCTTGTTGATCCTCTTACCCCGGCTGTAAAAGCT
GCAGCCAGAAACATGCGGAAAATTAAGGGTAAGGGAAATTAA

Upstream 100 bases:

>100_bases
AAAGATTCTAAAGGGAATTTTTTACAAGCAACCTGCCTTTAAAGAGCTTCTCAAGACTAATTTTGTATTTAAAAACATAT
AATAGGCGCGAAGCACCATT

Downstream 100 bases:

>100_bases
GGCAATGAAAGAAGCCCATATAAGTAATCAGGCTGGATATGAGGTTAAATAGCAAAATTAAGGCAAATGAATGAAATCTG
GATAAAAAGGAAAAATATTG

Product: NADH oxidase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MKSMGSNSGAKGTEGGSSRTEGEIQENISENASSNSRTEKEFAKVVIIGGGACGMATATKIRRQSDFDITVLSWDSHTAY
SHCGIPFVLGKEIESLKKLIVKPLAFFRENKINVKLNEKVTSIDLNGQVVITGEGTYPFDRLVIATGSLPFIPRESRANI
LPYGIFTLRSLADGMLFEKALETARTVCIIGGGTIGIECASALTKRGIRTTLITRGNDLLTRQFDSDMSAIVREHLESLG
VEVITGESVILPENFWKQKTLILRDRQLPADLVLLATGVKPETWLSRETGITIGKAGGIIVNEMLQVKAGEKFLSHVYAG
GECAEVIDLITGESRLSQLGTTARSMADVIGNNITGKHSTFGPLADPWVAVAGDLQFGGVGLTSGQAEKQGIKTVTGFSR
GRTRASYYPGRKDLYIKLLFKNNCLAGAQLAGGEGIKERIDALSLAIRKEATIKDLLNLETCYAPPVSTLVDPLTPAVKA
AARNMRKIKGKGN

Sequences:

>Translated_493_residues
MKSMGSNSGAKGTEGGSSRTEGEIQENISENASSNSRTEKEFAKVVIIGGGACGMATATKIRRQSDFDITVLSWDSHTAY
SHCGIPFVLGKEIESLKKLIVKPLAFFRENKINVKLNEKVTSIDLNGQVVITGEGTYPFDRLVIATGSLPFIPRESRANI
LPYGIFTLRSLADGMLFEKALETARTVCIIGGGTIGIECASALTKRGIRTTLITRGNDLLTRQFDSDMSAIVREHLESLG
VEVITGESVILPENFWKQKTLILRDRQLPADLVLLATGVKPETWLSRETGITIGKAGGIIVNEMLQVKAGEKFLSHVYAG
GECAEVIDLITGESRLSQLGTTARSMADVIGNNITGKHSTFGPLADPWVAVAGDLQFGGVGLTSGQAEKQGIKTVTGFSR
GRTRASYYPGRKDLYIKLLFKNNCLAGAQLAGGEGIKERIDALSLAIRKEATIKDLLNLETCYAPPVSTLVDPLTPAVKA
AARNMRKIKGKGN
>Mature_493_residues
MKSMGSNSGAKGTEGGSSRTEGEIQENISENASSNSRTEKEFAKVVIIGGGACGMATATKIRRQSDFDITVLSWDSHTAY
SHCGIPFVLGKEIESLKKLIVKPLAFFRENKINVKLNEKVTSIDLNGQVVITGEGTYPFDRLVIATGSLPFIPRESRANI
LPYGIFTLRSLADGMLFEKALETARTVCIIGGGTIGIECASALTKRGIRTTLITRGNDLLTRQFDSDMSAIVREHLESLG
VEVITGESVILPENFWKQKTLILRDRQLPADLVLLATGVKPETWLSRETGITIGKAGGIIVNEMLQVKAGEKFLSHVYAG
GECAEVIDLITGESRLSQLGTTARSMADVIGNNITGKHSTFGPLADPWVAVAGDLQFGGVGLTSGQAEKQGIKTVTGFSR
GRTRASYYPGRKDLYIKLLFKNNCLAGAQLAGGEGIKERIDALSLAIRKEATIKDLLNLETCYAPPVSTLVDPLTPAVKA
AARNMRKIKGKGN

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=361, Percent_Identity=24.0997229916898, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI226437568, Length=361, Percent_Identity=24.0997229916898, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI65787454, Length=361, Percent_Identity=24.0997229916898, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789065, Length=289, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789765, Length=398, Percent_Identity=27.1356783919598, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788892, Length=289, Percent_Identity=26.2975778546713, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24585130, Length=306, Percent_Identity=24.1830065359477, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281359715, Length=286, Percent_Identity=24.4755244755245, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359713, Length=286, Percent_Identity=24.4755244755245, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639250, Length=286, Percent_Identity=24.4755244755245, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18543267, Length=286, Percent_Identity=24.4755244755245, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639252, Length=286, Percent_Identity=24.4755244755245, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639257, Length=286, Percent_Identity=24.4755244755245, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 52965; Mature: 52965

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSMGSNSGAKGTEGGSSRTEGEIQENISENASSNSRTEKEFAKVVIIGGGACGMATATK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCEEEEEEECCCCCCHHHHHH
IRRQSDFDITVLSWDSHTAYSHCGIPFVLGKEIESLKKLIVKPLAFFRENKINVKLNEKV
HHCCCCCCEEEEECCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCEE
TSIDLNGQVVITGEGTYPFDRLVIATGSLPFIPRESRANILPYGIFTLRSLADGMLFEKA
EEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LETARTVCIIGGGTIGIECASALTKRGIRTTLITRGNDLLTRQFDSDMSAIVREHLESLG
HHHHCEEEEEECCEEHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VEVITGESVILPENFWKQKTLILRDRQLPADLVLLATGVKPETWLSRETGITIGKAGGII
EEEEECCEEECCCHHCCCCEEEEECCCCCCCEEEEECCCCCHHHCCCCCCEEEECCCCHH
VNEMLQVKAGEKFLSHVYAGGECAEVIDLITGESRLSQLGTTARSMADVIGNNITGKHST
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FGPLADPWVAVAGDLQFGGVGLTSGQAEKQGIKTVTGFSRGRTRASYYPGRKDLYIKLLF
CCCCCCCCEEEECCCEECCEECCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEE
KNNCLAGAQLAGGEGIKERIDALSLAIRKEATIKDLLNLETCYAPPVSTLVDPLTPAVKA
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCHHHHH
AARNMRKIKGKGN
HHHHHHHHCCCCC
>Mature Secondary Structure
MKSMGSNSGAKGTEGGSSRTEGEIQENISENASSNSRTEKEFAKVVIIGGGACGMATATK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCEEEEEEECCCCCCHHHHHH
IRRQSDFDITVLSWDSHTAYSHCGIPFVLGKEIESLKKLIVKPLAFFRENKINVKLNEKV
HHCCCCCCEEEEECCCCCCHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEEEEECCEE
TSIDLNGQVVITGEGTYPFDRLVIATGSLPFIPRESRANILPYGIFTLRSLADGMLFEKA
EEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LETARTVCIIGGGTIGIECASALTKRGIRTTLITRGNDLLTRQFDSDMSAIVREHLESLG
HHHHCEEEEEECCEEHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
VEVITGESVILPENFWKQKTLILRDRQLPADLVLLATGVKPETWLSRETGITIGKAGGII
EEEEECCEEECCCHHCCCCEEEEECCCCCCCEEEEECCCCCHHHCCCCCCEEEECCCCHH
VNEMLQVKAGEKFLSHVYAGGECAEVIDLITGESRLSQLGTTARSMADVIGNNITGKHST
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FGPLADPWVAVAGDLQFGGVGLTSGQAEKQGIKTVTGFSRGRTRASYYPGRKDLYIKLLF
CCCCCCCCEEEECCCEECCEECCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCEEEEEEE
KNNCLAGAQLAGGEGIKERIDALSLAIRKEATIKDLLNLETCYAPPVSTLVDPLTPAVKA
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCCHHHHH
AARNMRKIKGKGN
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]